Combined Photoredox and Carbene Catalysis for the Synthesis of α-Amino Ketones from Carboxylic Acids

Carbene-Catalyzed Alkylation of Carboxylic Esters via Direct Photoexcitation of Acyl Azolium Intermediates

(2021) Shi-Chao Ren et al.   ACS Catalysis

Direct α-Acylation of Alkenes via N-Heterocyclic Carbene, Sulfinate, and Photoredox Cooperative Triple Catalysis

(2021) Kun Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Benzylic C−H acylation by cooperative NHC and photoredox catalysis

(2021) Qing-Yuan Meng et al.   Nature Communications

Light‐Driven Carbene Catalysis for the Synthesis of Aliphatic and α‐Amino Ketones

(2021) Anna V. Bay et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A cross-dehydrogenative C(sp3)−H heteroarylation via photo-induced catalytic chlorine radical generation

(2021) Chia-Yu Huang et al.   Nature Communications

Combined Photoredox and Carbene Catalysis for the Synthesis of γ‐Aryloxy Ketones

(2021) Pengzhi Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Cooperative NHC/Photoredox Catalyzed Ring‐Opening of Aryl Cyclopropanes to 1‐Aroyloxylated‐3‐Acylated Alkanes

(2021) Zhijun Zuo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Light-Driven N-Heterocyclic Carbene Catalysis Using Alkylborates

(2021) Yukiya Sato et al.   ACS Catalysis

Combined Photoredox and Carbene Catalysis for the Synthesis of Ketones from Carboxylic Acids

(2020) Karl Scheidt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dehydrogenative Coupling of Benzylic and Aldehydic C–H Bonds

(2020) Tairin Kawasaki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHC-Catalyzed Radical Trifluoromethylation Enabled by Togni Reagent

(2020) Bei Zhang et al.   ORGANIC LETTERS

Photo/N-Heterocyclic Carbene Co-catalyzed Ring Opening and γ-Alkylation of Cyclopropane Enal

(2020) Lei Dai et al.   ORGANIC LETTERS

N-Heterocyclic Carbene-Catalyzed Radical Relay Enabling Synthesis of δ-Ketocarbonyls

(2020) Kenji Ota et al.   ORGANIC LETTERS

Cooperative NHC and Photoredox Catalysis for the Synthesis of β‐Trifluoromethylated Alkyl Aryl Ketones

(2020) Qing-Yuan Meng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Phosphoric Acid Catalyzed Enantioselective Synthesis of α-Tertiary Amino Ketones from Sulfonium Ylides

(2020) Wengang Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bio- and Medicinally Compatible α-Amino-Acid Modification via Merging Photoredox and N-Heterocyclic Carbene Catalysis

(2020) Ding Du et al.   ORGANIC LETTERS

Direct Synthesis of Dialkyl Ketones from Aliphatic Aldehydes through Radical N-Heterocyclic Carbene Catalysis

(2020) Yuki Kakeno et al.   ACS Catalysis

Catalytic, Metal-Free Amide Synthesis from Aldehydes and Imines Enabled by a Dual-Catalyzed Umpolung Strategy under Redox-Neutral Conditions

(2020) Ming-Shang Liu et al.   ACS Catalysis

Electrochemical Arylation of Aldehydes, Ketones and Alcohols: from Cathodic Reduction to Convergent Paired Electrolysis

(2020) Michael Findlater et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Addition of Prochiral Radicals to Vinylpyridines

(2019) Kangning Cao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbene-Catalyzed Decarboxylative Alkylation of Aldehydes

(2019) Takuya Ishii et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visible-Light-Mediated, Chemo- and Stereoselective Radical Process for the Synthesis of C-Glycoamino Acids

(2019) Peng Ji et al.   ORGANIC LETTERS

En Route to Intermolecular Cross-Dehydrogenative Coupling Reactions

(2019) Chia-Yu Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene-Catalyzed Radical Relay Enabling Vicinal Alkylacylation of Alkenes

(2019) Takuya Ishii et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Nitroarenes as Enantioselective Single-Electron-Transfer Oxidants for Carbene-Catalyzed Radical Reactions

(2019) Hongling Wang et al.   ORGANIC LETTERS

Visible-Light-Driven N-Heterocyclic Carbene Catalyzed γ- and ϵ -Alkylation with Alkyl Radicals

(2019) Lei Dai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Radical Acylfluoroalkylation of Olefins through N-Heterocyclic Carbene Organocatalysis

(2019) Jun-Long Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Method for the Catalytic Enantioselective Synthesis of Chiral α-Azido and α-Amino Ketones from Racemic α-Bromo Ketones, and Its Generalization to the Formation of Bonds to C, O, and S

(2019) Roberto da Silva Gomes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visible light-promoted alkylation of imines using potassium organotrifluoroborates

(2018) Davis P. Plasko et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Copper(II)-Catalyzed Asymmetric Photoredox Reactions: Enantioselective Alkylation of Imines Driven by Visible Light

(2018) Yanjun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Method for the Direct Enantioselective Synthesis of Chiral Primary α-Amino Ketones by Catalytic α-Amination

(2018) Yixin Han et al.   ORGANIC LETTERS

Acyl Radical Chemistry via Visible-Light Photoredox Catalysis

(2018) Ming-Yu Ngai et al.   SYNTHESIS-STUTTGART

Domino-Fluorination–Protodefluorination Enables Decarboxylative Cross-Coupling of α-Oxocarboxylic Acids with Styrene via Photoredox Catalysis

(2017) Muliang Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Radical Alkylation of Imines with 4-Alkyl-1,4-dihydropyridines Enabled by Photoredox/Brønsted Acid Cocatalysis

(2017) Hong-Hao Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct Aldehyde C–H Arylation and Alkylation via the Combination of Nickel, Hydrogen Atom Transfer, and Photoredox Catalysis

(2017) Xiaheng Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemo- and Regioselective Organo-Photoredox Catalyzed Hydroformylation of Styrenes via a Radical Pathway

(2017) He Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbene-Catalyzed Reductive Coupling of Nitrobenzyl Bromide and Nitroalkene via the Single-Electron-Transfer (SET) Process and Formal 1,4-Addition

(2017) Yuhuang Wang et al.   ORGANIC LETTERS

N-Heterocyclic carbene-catalyzed oxidative [3 + 2] annulation of dioxindoles and enals: cross coupling of homoenolate and enolate

(2017) Xiang-Yu Chen et al.   Chemical Science

N-Heterocyclic Carbene Catalysis via the α,β-Unsaturated Acyl Azolium

(2017) Changhe Zhang et al.   ACS Catalysis

Mild, Redox-Neutral Alkylation of Imines Enabled by an Organic Photocatalyst

(2017) Niki R. Patel et al.   ACS Catalysis

N-Heterocyclic Carbene Catalyzed γ-Dihalomethylenation of Enals by Single-Electron Transfer

(2016) Wen Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Acylation of C(sp3 )−H Bonds Enabled by Nickel and Photoredox Catalysis

(2016) Candice L. Joe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organic Photoredox Catalysis

(2016) Nathan A. Romero et al.   CHEMICAL REVIEWS

Dual Catalysis Strategies in Photochemical Synthesis

(2016) Kazimer L. Skubi et al.   CHEMICAL REVIEWS

Photoredox Catalysis in Organic Chemistry

(2016) Megan H. Shaw et al.   JOURNAL OF ORGANIC CHEMISTRY

The Photocatalyzed Aza-Henry Reaction of N-Aryltetrahydroisoquinolines: Comprehensive Mechanism, H•- versus H+-Abstraction, and Background Reactions

(2016) Hanna Bartling et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Frustrated Lewis Acid/Brønsted Base Catalysts for Direct Enantioselective α-Amination of Carbonyl Compounds

(2016) Ming Shang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbene-catalysed reductive coupling of nitrobenzyl bromides and activated ketones or imines via single-electron-transfer process

(2016) Bao-Sheng Li et al.   Nature Communications

Stereoselective Actions of Methylenedioxypyrovalerone (MDPV) To Inhibit Dopamine and Norepinephrine Transporters and Facilitate Intracranial Self-Stimulation in Rats

(2015) R. Kolanos et al.   ACS Chemical Neuroscience

Merging Photoredox and Nickel Catalysis: The Direct Synthesis of Ketones by the Decarboxylative Arylation of α-Oxo Acids

(2015) Lingling Chu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes

(2015) Darrin M. Flanigan et al.   CHEMICAL REVIEWS

N-Heterocyclic Carbene-Catalyzed Radical Reactions for Highly Enantioselective β-Hydroxylation of Enals

(2015) Yuexia Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Asymmetric Amination of α-Branched Cyclic Ketones Catalyzed by a Chiral Phosphoric Acid

(2015) Xiaoyu Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Nucleophilic Strategy for Enantioselective Intermolecular α-Amination: Access to Enantioenriched α-Arylamino Ketones

(2015) Dillon H. Miles et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxidatively Initiated NHC-Catalyzed Enantioselective Synthesis of 3,4-Disubstituted Cyclopentanones from Enals

(2015) Nicholas A. White et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective NH Insertion Reaction of α-Aryl α-Diazoketones: An Efficient Route to Chiral α-Aminoketones

(2014) Bin Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Redox catalysis in organic electrosynthesis: basic principles and recent developments

(2014) Robert Francke et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective N-Heterocyclic Carbene-Catalyzed β-Hydroxylation of Enals Using Nitroarenes: An Atom Transfer Reaction That Proceeds via Single Electron Transfer

(2014) Nicholas A. White et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

N-Heterocyclic Carbene Organocatalytic Reductive β,β-Coupling Reactions of Nitroalkenes via Radical Intermediates

(2014) Yu Du et al.   ORGANIC LETTERS

Hybrid Dopamine Uptake Blocker–Serotonin Releaser Ligands: A New Twist on Transporter-Focused Therapeutics

(2014) Bruce E. Blough et al.   ACS Medicinal Chemistry Letters

The Cross-Dehydrogenative Coupling of C sp 3H Bonds: A Versatile Strategy for CC Bond Formations

(2013) Simon A. Girard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Electrophilic α-Amination of α-Alkyl-β-Ketoesters with In Situ Generated Nitrosoformates

(2013) Philipp Selig   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible-Light-Mediated Decarboxylation/Oxidative Amidation of α-Keto Acids with Amines under Mild Reaction Conditions Using O2

(2013) Jie Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis

(2013) Christopher K. Prier et al.   CHEMICAL REVIEWS

Development of a Chiral Bis(guanidino)iminophosphorane as an Uncharged Organosuperbase for the Enantioselective Amination of Ketones

(2013) Tadahiro Takeda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aerobic oxidation of aldehydes by visible light photocatalysis

(2013) Naeem Iqbal et al.   TETRAHEDRON LETTERS

Exploiting Acyl and Enol Azolium Intermediates via N-Hetero- cyclic Carbene-Catalyzed Reactions of α-Reducible Aldehydes

(2012) Harit U. Vora et al.   ADVANCED SYNTHESIS & CATALYSIS

Visible-Light Photoredox Catalysis

(2012) Jun Xuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Polarity Reversal Catalysis in Radical Reductions of Halides by N-Heterocyclic Carbene Boranes

(2012) Xiangcheng Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric α-Acylation of Tertiary Amines Mediated by a Dual Catalysis Mode: N-Heterocyclic Carbene and Photoredox Catalysis

(2012) Daniel A. DiRocco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visible-Light-Induced Oxidation/[3+2] Cycloaddition/Oxidative Aromatization Sequence: A Photocatalytic Strategy To Construct Pyrrolo[2,1-a]isoquinolines

(2011) You-Quan Zou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New Electrophilic Addition of α-Diazoesters with Ketones for Enantioselective C–N Bond Formation

(2011) Wei Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Eosin Y Catalyzed Visible Light Oxidative C–C and C–P bond Formation

(2011) Durga Prasad Hari et al.   ORGANIC LETTERS

Transition Metal Catalyzed Enantioselective α-Heterofunctionalization of Carbonyl Compounds

(2010) Alexander M. R. Smith et al.   CHEMICAL REVIEWS

NHC Catalyzed Oxidations of Aldehydes to Esters: Chemoselective Acylation of Alcohols in Presence of Amines

(2010) Suman De Sarkar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visible-Light Photoredox Catalysis: Aza-Henry Reactions via C−H Functionalization

(2010) Allison G. Condie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalyzed Asymmetric α-Oxidation, α-Aminoxylation and α-Amination of Carbonyl Compounds

(2010) Tirayut Vilaivan et al.   MOLECULES

Visible light photocatalysis as a greener approach to photochemical synthesis

(2010) Tehshik P. Yoon et al.   Nature Chemistry

Enantioselective α-Amination of 1,3-Dicarbonyl Compounds Using Squaramide Derivatives as Hydrogen Bonding Catalysts

(2010) Hideyuki Konishi et al.   ORGANIC LETTERS

Synthesis and Biological Evaluation of Bupropion Analogues as Potential Pharmacotherapies for Cocaine Addiction

(2009) F. Ivy Carroll et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cross-Dehydrogenative Coupling (CDC): Exploring C−C Bond Formations beyond Functional Group Transformations

(2008) Chao-Jun Li   ACCOUNTS OF CHEMICAL RESEARCH

Biomimetic Carbene-Catalyzed Oxidations of Aldehydes Using TEMPO

(2008) Joyram Guin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene-Catalyzed Oxidation of Unactivated Aldehydes to Esters

(2008) Brooks E. Maki et al.   ORGANIC LETTERS

New catalytic transformations of carboxylic acids

(2008) Lukas J. Gooßen et al.   PURE AND APPLIED CHEMISTRY