Exploiting Acyl and Enol Azolium Intermediates via N-Hetero- cyclic Carbene-Catalyzed Reactions of α-Reducible Aldehydes

Organic Synthesis without Stoichiometric Reagents: A Guiding Principle for Reaction Development

(2012) Jeffrey W. Bode   CHIMIA

Extending NHC-Catalysis: Coupling Aldehydes with Unconventional Reaction Partners

(2011) Akkattu T. Biju et al.   ACCOUNTS OF CHEMICAL RESEARCH

Lewis Acid Activated Synthesis of Highly Substituted Cyclopentanes by the N-Heterocyclic Carbene Catalyzed Addition of Homoenolate Equivalents to Unsaturated Ketoesters

(2011) Daniel T. Cohen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

α,β-Unsaturated Acyl Azoliums from N-Heterocyclic Carbene Catalyzed Reactions: Observation and Mechanistic Investigation

(2011) Jessada Mahatthananchai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemoselective conversion of α-unbranched aldehydes to amides, esters, and carboxylic acids by NHC-catalysis

(2011) Satoru Kuwano et al.   CHEMICAL COMMUNICATIONS

Employing homoenolates generated by NHC catalysis in carbon–carbon bond-forming reactions: state of the art

(2011) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

Dual Activation in N-Heterocyclic Carbene-organocatalysis

(2011) Keiichi Hirano et al.   CHEMISTRY LETTERS

Mechanistic Insights on N-Heterocyclic Carbene-Catalyzed Annulations: The Role of Base-Assisted Proton Transfers

(2011) Pragya Verma et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Syntheses of the Histone Deacetylase Inhibitors Largazole and 2-epi-Largazole: Application ofN-Heterocyclic Carbene Mediated Acylations in Complex Molecule Synthesis

(2011) Bo Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Kinetic Resolution of Cyclic Secondary Amines

(2011) Michael Binanzer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbene and Brønsted Acid Cooperative Catalysis: Asymmetric Synthesis oftrans-γ-Lactams

(2011) Xiaodan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Diels–Alder Reactions of Enals and Alkylidene Diketones Catalyzed by N-Heterocyclic Carbenes

(2011) Xinqiang Fang et al.   ORGANIC LETTERS

Cooperative Lewis acid/N-heterocyclic carbene catalysis

(2011) Daniel T. Cohen et al.   Chemical Science

Otto Wallach: Founder of Terpene Chemistry and Nobel Laureate 1910

(2010) Mathias Christmann   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

α-Aroyloxyaldehydes: scope and limitations as alternatives to α-haloaldehydes for NHC-catalysed redox transformations

(2010) Kenneth B. Ling et al.   CHEMICAL COMMUNICATIONS

N-Heterocyclic Carbene Catalyzed Asymmetric Hydration: Direct Synthesis of α-Protio and α-Deuterio α-Chloro and α-Fluoro Carboxylic Acids

(2010) Harit U. Vora et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CooperativeN-Heterocyclic Carbene/Lewis Acid Catalysis for Highly Stereoselective Annulation Reactions with Homoenolates

(2010) Benoit Cardinal-David et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Enantioselective Claisen Rearrangement Catalyzed by N-Heterocyclic Carbenes

(2010) Juthanat Kaeobamrung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHC Catalyzed Oxidations of Aldehydes to Esters: Chemoselective Acylation of Alcohols in Presence of Amines

(2010) Suman De Sarkar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative catalysis by carbenes and Lewis acids in a highly stereoselective route to γ-lactams

(2010) Dustin E. A. Raup et al.   Nature Chemistry

NHC-Catalyzed Intramolecular Redox Amidation for the Synthesis of Functionalized Lactams

(2010) Karen Thai et al.   ORGANIC LETTERS

Oxidative Amidation and Azidation of Aldehydes by NHC Catalysis

(2010) Suman De Sarkar et al.   ORGANIC LETTERS

Organocatalytic Preparation of Simple β-Hydroxy and β-Amino Esters: Low Catalyst Loadings and Gram-Scale Synthesis

(2010) Hao Jiang et al.   ORGANIC LETTERS

Chiral N-heterocyclic carbene-catalyzed generation of ester enolate equivalents from  , -unsaturated aldehydes for enantioselective Diels-Alder reactions

(2010) J. Kaeobamrung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redox Economy in Organic Synthesis

(2009) Noah Z. Burns et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic amide formation with α′-hydroxyenones as acylating reagents

(2009) Pei-Chen Chiang et al.   CHEMICAL COMMUNICATIONS

The economies of synthesis

(2009) Timothy Newhouse et al.   CHEMICAL SOCIETY REVIEWS

An Efficient Carbene-Catalyzed Access to 3,4-Dihydrocoumarins

(2009) Kirsten Zeitler et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene-Catalyzed Enantioselective Mannich Reactions with α-Aryloxyacetaldehydes

(2009) Yasufumi Kawanaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

α′-Hydroxyenones as Mechanistic Probes and Scope-Expanding Surrogates for α,β-Unsaturated Aldehydes in N-Heterocyclic Carbene-Catalyzed Reactions

(2009) Pei-Chen Chiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergency of Triazolium and Imidazolium-Derived NHCs for Catalytic, Enantioselective Cyclopentane Synthesis

(2009) Juthanat Kaeobamrung et al.   ORGANIC LETTERS

NHC-Catalyzed Ring Expansion of Oxacycloalkane-2-carboxaldehydes: A Versatile Synthesis of Lactones

(2009) Li Wang et al.   ORGANIC LETTERS

Nucleophilic Heterocyclic Carbene Catalyzed Annulation of Enals to Chalcones in Methanol: A Stereoselective Synthesis of Highly Functionalized Cyclopentanes§

(2009) Vijay Nair et al.   ORGANIC LETTERS

N-Heterocyclic Carbene Catalyzed Ring Expansion of Formylcyclopropanes: Synthesis of 3,4-Dihydro-α-pyrone Derivatives

(2009) Gong-Qiang Li et al.   ORGANIC LETTERS

Impact of Solvent Polarity on N-Heterocyclic Carbene-Catalyzed β-Protonations of Homoenolate Equivalents

(2009) Brooks E. Maki et al.   ORGANIC LETTERS

Enantioselective Synthesis ofcis-4-Formyl-β-lactamsviaChiral N-Heterocyclic Carbene-Catalyzed Kinetic Resolution

(2008) Gong-Qiang Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Stereoselective Synthesis of γ-ButyrolactonesviaOrganocatalytic Annulations of Enals and Keto Esters

(2008) Yi Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Recent advances in carbon–carbon bond-forming reactions involving homoenolates generated by NHC catalysis

(2008) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

Nucleophilic Carbene Catalyzed Synthesis of 1,2 Amino Alcohols Via Azidation of Epoxy Aldehydes

(2008) Harit U. Vora et al.   JOURNAL OF ORGANIC CHEMISTRY

Cyclic Ketimines as Superior Electrophiles for NHC-Catalyzed Homoenolate Additions with Broad Scope and Low Catalyst Loadings

(2008) Michael Rommel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Amination of Homoenolates Catalyzed byN-Heterocyclic Carbenes

(2008) Audrey Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Diastereo- and Enantioselective Additions of Homoenolates to Nitrones Catalyzed byN-Heterocyclic Carbenes

(2008) Eric M. Phillips et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral NHC-Catalyzed Oxodiene Diels−Alder Reactions with α-Chloroaldehyde Bisulfite Salts

(2008) Ming He et al.   ORGANIC LETTERS

NHC-Catalyzed Reactions of Aryloxyacetaldehydes: A Domino Elimination/Conjugate Addition/Acylation Process for the Synthesis of Substituted Coumarins

(2008) Eric M. Phillips et al.   ORGANIC LETTERS

Stereoselective synthesis of spirocyclopentanones viaN-heterocyclic carbene-catalyzed reactions of enals and dienones

(2007) Vijay Nair et al.   CHEMICAL COMMUNICATIONS

Enantioselective, NHC-Catalyzed Bicyclo-β-Lactam Formation via Direct Annulations of Enals and UnsaturatedN-Sulfonyl Ketimines

(2007) Ming He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY