- Home
- Publications
- Publication Search
- Publication Details
Title
Genome-wide detection of CRISPR editing in vivo using GUIDE-tag
Authors
Keywords
-
Journal
Nature Communications
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-01-21
DOI
10.1038/s41467-022-28135-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Genome-wide specificity of prime editors in plants
- (2021) Shuai Jin et al. NATURE BIOTECHNOLOGY
- 5′-Modifications improve potency and efficacy of DNA donors for precision genome editing
- (2021) Krishna S Ghanta et al. eLife
- CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors
- (2020) Dan Wang et al. CELL
- Highly Parallel Profiling of Cas9 Variant Specificity
- (2020) Jonathan L. Schmid-Burgk et al. MOLECULAR CELL
- Improving the efficiency of precise genome editing with site-specific Cas9-oligonucleotide conjugates
- (2020) Xinyu Ling et al. Science Advances
- CHANGE-seq reveals genetic and epigenetic effects on CRISPR–Cas9 genome-wide activity
- (2020) Cicera R. Lazzarotto et al. NATURE BIOTECHNOLOGY
- Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System
- (2020) Jenny Shapiro et al. Molecular Therapy-Methods & Clinical Development
- Enhanced Cas12a editing in mammalian cells and zebrafish
- (2019) Pengpeng Liu et al. NUCLEIC ACIDS RESEARCH
- Highly efficient therapeutic gene editing of human hematopoietic stem cells
- (2019) Yuxuan Wu et al. NATURE MEDICINE
- Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy
- (2019) Christopher E. Nelson et al. NATURE MEDICINE
- Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing
- (2019) Benjamin P. Kleinstiver et al. NATURE BIOTECHNOLOGY
- Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases
- (2019) Daesik Kim et al. Annual Review of Biochemistry
- Increasing the specificity of CRISPR systems with engineered RNA secondary structures
- (2019) D. Dewran Kocak et al. NATURE BIOTECHNOLOGY
- Microhomologies are prevalent at Cas9-induced larger deletions
- (2019) Dominic D G Owens et al. NUCLEIC ACIDS RESEARCH
- Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia
- (2019) Sateesh Krishnamurthy et al. Nature Communications
- Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency
- (2019) David N. Nguyen et al. NATURE BIOTECHNOLOGY
- UDiTaS™, a genome editing detection method for indels and genome rearrangements
- (2018) Georgia Giannoukos et al. BMC GENOMICS
- Cas9-nickase–mediated genome editing corrects hereditary tyrosinemia in rats
- (2018) Yanjiao Shao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Efficient generation of targeted large insertions by microinjection into two-cell-stage mouse embryos
- (2018) Bin Gu et al. NATURE BIOTECHNOLOGY
- Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements
- (2018) Michael Kosicki et al. NATURE BIOTECHNOLOGY
- A highly specific SpCas9 variant is identified by in vivo screening in yeast
- (2018) Antonio Casini et al. NATURE BIOTECHNOLOGY
- Partial DNA-guided Cas9 enables genome editing with reduced off-target activity
- (2018) Hao Yin et al. Nature Chemical Biology
- Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair
- (2018) Natasa Savic et al. eLife
- In vivo CRISPR editing with no detectable genome-wide off-target mutations
- (2018) Pinar Akcakaya et al. NATURE
- Evolved Cas9 variants with broad PAM compatibility and high DNA specificity
- (2018) Johnny H. Hu et al. NATURE
- A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells
- (2018) Christopher A. Vakulskas et al. NATURE MEDICINE
- DIG-seq: a genome-wide CRISPR off-target profiling method using chromatin DNA
- (2018) Daesik Kim et al. GENOME RESEARCH
- Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
- (2017) Janice S. Chen et al. NATURE
- The chemical evolution of oligonucleotide therapies of clinical utility
- (2017) Anastasia Khvorova et al. NATURE BIOTECHNOLOGY
- Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes
- (2017) Brett T Staahl et al. NATURE BIOTECHNOLOGY
- A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo
- (2017) Zoë N Rogers et al. NATURE METHODS
- Mapping the genomic landscape of CRISPR–Cas9 cleavage
- (2017) Peter Cameron et al. NATURE METHODS
- CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets
- (2017) Shengdar Q Tsai et al. NATURE METHODS
- Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci
- (2017) Samuel Lessard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CRISPR/Cas9 – Mediated Precise Targeted Integration In Vivo Using a Double Cut Donor with Short Homology Arms
- (2017) Xuan Yao et al. EBioMedicine
- In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration
- (2016) Keiichiro Suzuki et al. NATURE
- High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
- (2016) Benjamin P. Kleinstiver et al. NATURE
- Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
- (2016) John G Doench et al. NATURE BIOTECHNOLOGY
- Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
- (2016) Hao Yin et al. NATURE BIOTECHNOLOGY
- Knock-in of large reporter genes in human cells via CRISPR/Cas9-induced homology-dependent and independent DNA repair
- (2016) Xiangjun He et al. NUCLEIC ACIDS RESEARCH
- In vivo genome editing using Staphylococcus aureus Cas9
- (2015) F. Ann Ran et al. NATURE
- Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
- (2015) Daesik Kim et al. NATURE METHODS
- Rationally engineered Cas9 nucleases with improved specificity
- (2015) I. M. Slaymaker et al. SCIENCE
- Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
- (2014) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases
- (2014) Richard L Frock et al. NATURE BIOTECHNOLOGY
- CRISPRseek: A Bioconductor Package to Identify Target-Specific Guide RNAs for CRISPR-Cas9 Genome-Editing Systems
- (2014) Lihua J. Zhu et al. PLoS One
- Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair
- (2013) T. O. Auer et al. GENOME RESEARCH
- DNA targeting specificity of RNA-guided Cas9 nucleases
- (2013) Patrick D Hsu et al. NATURE BIOTECHNOLOGY
- High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
- (2013) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Fast and accurate long-read alignment with Burrows–Wheeler transform
- (2010) Heng Li et al. BIOINFORMATICS
- A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
- (2009) Linda Madisen et al. NATURE NEUROSCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation