Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System

Published 2020 View Full Article

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Title
Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System
Authors
Keywords
genome editing, CRISPR-Cas9, CD34, hematopoietic stem and progenitor cells, chemically modified guide RNAs, off-target sites
Journal
Molecular Therapy-Methods & Clinical Development
Volume 17, Issue -, Pages 1097-1107
Publisher
Elsevier BV
Online
2020-05-05
DOI
10.1016/j.omtm.2020.04.027

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