Increasing the specificity of CRISPR systems with engineered RNA secondary structures
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Increasing the specificity of CRISPR systems with engineered RNA secondary structures
Authors
Keywords
-
Journal
NATURE BIOTECHNOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2019-04-16
DOI
10.1038/s41587-019-0095-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- CasX enzymes comprise a distinct family of RNA-guided genome editors
- (2019) Jun-Jie Liu et al. NATURE
- Chimeric Guides Probe and Enhance Cas9 Biochemical Activity
- (2018) Zachary J. Kartje et al. BIOCHEMISTRY
- Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors
- (2018) Silvana Konermann et al. CELL
- A highly specific SpCas9 variant is identified by in vivo screening in yeast
- (2018) Antonio Casini et al. NATURE BIOTECHNOLOGY
- Partial DNA-guided Cas9 enables genome editing with reduced off-target activity
- (2018) Hao Yin et al. Nature Chemical Biology
- A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells
- (2018) Christopher A. Vakulskas et al. NATURE MEDICINE
- Directed evolution of CRISPR-Cas9 to increase its specificity
- (2018) Jungjoon K. Lee et al. Nature Communications
- Defining CRISPR–Cas9 genome-wide nuclease activities with CIRCLE-seq
- (2018) Cicera R. Lazzarotto et al. Nature Protocols
- Functionally diverse type V CRISPR-Cas systems
- (2018) Winston X. Yan et al. SCIENCE
- Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
- (2018) Lucas B. Harrington et al. SCIENCE
- Minimal PAM specificity of a highly similar SpCas9 ortholog
- (2018) Pranam Chatterjee et al. Science Advances
- Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
- (2017) Janice S. Chen et al. NATURE
- RNA targeting with CRISPR–Cas13
- (2017) Omar O. Abudayyeh et al. NATURE
- CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets
- (2017) Shengdar Q Tsai et al. NATURE METHODS
- High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
- (2017) Evan A. Boyle et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni
- (2017) Eunji Kim et al. Nature Communications
- BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks
- (2017) Winston X. Yan et al. Nature Communications
- A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9
- (2017) Yavuz S. Dagdas et al. Science Advances
- Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA
- (2016) Takashi Yamano et al. CELL
- Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
- (2016) Addison V. Wright et al. CELL
- Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq
- (2016) Daesik Kim et al. GENOME RESEARCH
- Genome-editing Technologies for Gene and Cell Therapy
- (2016) Morgan L Maeder et al. MOLECULAR THERAPY
- The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
- (2016) Ines Fonfara et al. NATURE
- New CRISPR–Cas systems from uncultivated microbes
- (2016) David Burstein et al. NATURE
- High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
- (2016) Benjamin P. Kleinstiver et al. NATURE
- Analyzing CRISPR genome-editing experiments with CRISPResso
- (2016) Luca Pinello et al. NATURE BIOTECHNOLOGY
- Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells
- (2016) Benjamin P Kleinstiver et al. NATURE BIOTECHNOLOGY
- Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells
- (2016) Daesik Kim et al. NATURE BIOTECHNOLOGY
- Applications of CRISPR technologies in research and beyond
- (2016) Rodolphe Barrangou et al. NATURE BIOTECHNOLOGY
- Internal guide RNA interactions interfere with Cas9-mediated cleavage
- (2016) Summer B. Thyme et al. Nature Communications
- Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds
- (2015) Jesse G. Zalatan et al. CELL
- Crystal Structure of Staphylococcus aureus Cas9
- (2015) Hiroshi Nishimasu et al. CELL
- Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
- (2015) Bernd Zetsche et al. CELL
- Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems
- (2015) Sergey Shmakov et al. MOLECULAR CELL
- Conformational control of DNA target cleavage by CRISPR–Cas9
- (2015) Samuel H. Sternberg et al. NATURE
- In vivo genome editing using Staphylococcus aureus Cas9
- (2015) F. Ann Ran et al. NATURE
- Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition
- (2015) Benjamin P Kleinstiver et al. NATURE BIOTECHNOLOGY
- Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease
- (2015) James E Dahlman et al. NATURE BIOTECHNOLOGY
- Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
- (2015) Isaac B Hilton et al. NATURE BIOTECHNOLOGY
- DNA-binding-domain fusions enhance the targeting range and precision of Cas9
- (2015) Mehmet Fatih Bolukbasi et al. NATURE METHODS
- Cas9 gRNA engineering for genome editing, activation and repression
- (2015) Samira Kiani et al. NATURE METHODS
- Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage
- (2015) Eric A. Josephs et al. NUCLEIC ACIDS RESEARCH
- Rationally engineered Cas9 nucleases with improved specificity
- (2015) I. M. Slaymaker et al. SCIENCE
- In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy
- (2015) C. E. Nelson et al. SCIENCE
- Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
- (2014) Luke A. Gilbert et al. CELL
- Guide RNA Functional Modules Direct Cas9 Activity and Orthogonality
- (2014) Alexandra E. Briner et al. MOLECULAR CELL
- Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
- (2014) Xuebing Wu et al. NATURE BIOTECHNOLOGY
- Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
- (2014) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease
- (2014) Cem Kuscu et al. NATURE BIOTECHNOLOGY
- Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification
- (2014) John P Guilinger et al. NATURE BIOTECHNOLOGY
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects
- (2014) Bin Shen et al. NATURE METHODS
- Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
- (2013) F. Ann Ran et al. CELL
- RNA-guided gene activation by CRISPR-Cas9–based transcription factors
- (2013) Pablo Perez-Pinera et al. NATURE METHODS
- Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis
- (2013) Z. Hou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Vienna RNA Websuite
- (2008) A. R. Gruber et al. NUCLEIC ACIDS RESEARCH
- Structures, Kinetics, Thermodynamics, and Biological Functions of RNA Hairpins
- (2007) Philip C. Bevilacqua et al. Annual Review of Physical Chemistry
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now