Fascin enhances the vulnerability of breast cancer to erastin-induced ferroptosis

Fascin actin-bundling protein 1 in human cancer: Promising biomarker or therapeutic target?

(2021) Hongliang Liu et al.   Molecular Therapy-Oncolytics

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Broadening horizons: the role of ferroptosis in cancer

(2021) Xin Chen et al.   Nature Reviews Clinical Oncology

Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes

(2021) Christina M. Bebber et al.   Nature Communications

CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer

(2020) Haiyang Zhang et al.   Molecular Cancer

How does fascin promote cancer metastasis?

(2020) Shengchen Lin et al.   FEBS Journal

MicroRNA-488 inhibits proliferation and motility of tumor cells via downregulating FSCN1, modulated by Notch3 in breast carcinomas

(2020) Yang Wu et al.   Cell Death & Disease

Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy

(2020) Pranavi Koppula et al.   Protein & Cell

Fascin in Cell Migration: More Than an Actin Bundling Protein

(2020) Maureen C. Lamb et al.   Biology-Basel

Insights into Molecular Classifications of Triple-Negative Breast Cancer: Improving Patient Selection for Treatment

(2019) Ana C. Garrido-Castro et al.   Cancer Discovery

The deubiquitylase OTUB1 mediates ferroptosis via stabilization of SLC7A11

(2019) Tong Liu et al.   CANCER RESEARCH

FSCN1 is an effective marker of poor prognosis and a potential therapeutic target in human tongue squamous cell carcinoma

(2019) Yue Chen et al.   Cell Death & Disease

Sphingosine-kinase-1 signaling promotes metastasis of triple-negative breast cancer

(2019) Sunil Acharya et al.   CANCER RESEARCH

Mass spectrometry‐based proteomic analysis of FSCN1‐interacting proteins in laryngeal squamous cell carcinoma cells

(2019) Hongliang Liu et al.   IUBMB LIFE

The long noncoding RNA H19 promotes tamoxifen resistance in breast cancer via autophagy

(2019) Ji Wang et al.   Journal of Hematology & Oncology

Down‐regulation of long noncoding RNA PVT 1 inhibits esophageal carcinoma cell migration and invasion and promotes cell apoptosis via micro RNA ‐145‐mediated inhibition of FSCN 1

(2019) Si‐Ning Shen et al.   Molecular Oncology

Metadherin enhances vulnerability of cancer cells to ferroptosis

(2019) Jianling Bi et al.   Cell Death & Disease

Targeting YAP1/LINC00152/FSCN1 Signaling Axis Prevents the Progression of Colorectal Cancer

(2019) Chunlin Ou et al.   Advanced Science

Fascin induces melanoma tumorigenesis and stemness through regulating the Hippo pathway

(2018) Jiaxin Kang et al.   Cell Communication and Signaling

Breast cancer

(2017) Nadia Harbeck et al.   LANCET

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

(2017) Vasanthi S. Viswanathan et al.   NATURE

LinkedOmics: analyzing multi-omics data within and across 32 cancer types

(2017) Suhas V Vasaikar et al.   NUCLEIC ACIDS RESEARCH

ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner

(2017) D Chen et al.   ONCOGENE

Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis

(2017) Z Fan et al.   Oncogenesis

Metallothionein-1G facilitates sorafenib resistance through inhibition of ferroptosis

(2016) Xiaofang Sun et al.   HEPATOLOGY

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Fascin Is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self-Renewal Pathway

(2016) Rayanah Barnawi et al.   STEM CELLS

Fascin 1 promoted the growth and migration of non-small cell lung cancer cells by activating YAP/TEAD signaling

(2016) Zhigang Liang et al.   TUMOR BIOLOGY

Insights into a novel nuclear function for Fascin in the regulation of the amino-acid transporter SLC3A2

(2016) Amine Saad et al.   Scientific Reports

Fascin-1 as a novel diagnostic marker of triple-negative breast cancer

(2016) Chao-Qun Wang et al.   Cancer Medicine

A Signal Transducer and Activator of Transcription 3·Nuclear Factor κB (Stat3·NFκB) Complex Is Necessary for the Expression of Fascin in Metastatic Breast Cancer Cells in Response to Interleukin (IL)-6 and Tumor Necrosis Factor (TNF)-α

(2014) Marylynn Snyder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

(2014) Scott J Dixon et al.   eLife

Loss of miR-133a expression associated with poor survival of breast cancer and restoration of miR-133a expression inhibited breast cancer cell growth and invasion

(2012) Zheng-sheng Wu et al.   BMC CANCER

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

The oxidative stress-inducible cystine/glutamate antiporter, system x c − : cystine supplier and beyond

(2011) Marcus Conrad et al.   AMINO ACIDS

Signal Transducers and Activators of Transcription 3 (STAT3) Directly Regulates Cytokine-induced Fascin Expression and Is Required for Breast Cancer Cell Migration

(2011) Marylynn Snyder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fascin1 expression predicts poor prognosis in patients with nasopharyngeal carcinoma and correlates with tumor invasion

(2009) D. Wu et al.   ANNALS OF ONCOLOGY