AMPK agonist alleviate renal tubulointerstitial fibrosis via activating mitophagy in high fat and streptozotocin induced diabetic mice

Mitophagy in Acute Kidney Injury and Kidney Repair

(2020) Ying Wang et al.   Cells

Dendropanax morbifera Protects against Renal Fibrosis in Streptozotocin-Induced Diabetic Rats

(2020) Richa Sachan et al.   Antioxidants

Metformin rescues Parkin protein expression and mitophagy in high glucose-challenged human renal epithelial cells by inhibiting NF-κB via PP2A activation

(2020) Yulan Zhao et al.   LIFE SCIENCES

Mitochondria targeted peptide SS-31 prevent on cisplatin-induced acute kidney injury via regulating mitochondrial ROS-NLRP3 pathway

(2020) Shi-kun Yang et al.   BIOMEDICINE & PHARMACOTHERAPY

Targeting AMPK signaling pathway by natural products for treatment of diabetes mellitus and its complications

(2019) Tanuj Joshi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation

(2019) Qisheng Lin et al.   Redox Biology

Metformin reduces TRPC6 expression through AMPK activation and modulates cytoskeleton dynamics in podocytes under diabetic conditions

(2019) Maria Szrejder et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK

(2019) Yu Wang et al.   Cell Reports

Metformin alleviates oxidative stress and enhances autophagy in diabetic kidney disease via AMPK/SIRT1-FoxO1 pathway

(2019) Huiwen Ren et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Advanced Oxidation Protein Products Aggravate Tubulointerstitial Fibrosis Through Protein Kinase C-Dependent Mitochondrial Injury in Early Diabetic Nephropathy

(2018) Xiao Li et al.   ANTIOXIDANTS & REDOX SIGNALING

Electron tomography of whole cultured cells using novel transmission electron imaging technique

(2018) Taiga Okumura et al.   MICRON

Mitochondrial dysfunction in diabetic kidney disease

(2018) Josephine M. Forbes et al.   Nature Reviews Nephrology

Optineurin-mediated mitophagy protects renal tubular epithelial cells against accelerated senescence in diabetic nephropathy

(2018) Kehong Chen et al.   Cell Death & Disease

Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis

(2018) Yachun Han et al.   Redox Biology

Targeting AMPK in Diabetes and Diabetic Complications: Energy homeostasis, Autophagy and Mitochondrial health

(2018) Y. V. Madhavi et al.   CURRENT MEDICINAL CHEMISTRY

NLRP3 deficiency ameliorates renal inflammation and fibrosis in diabetic mice

(2018) Ming Wu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Metformin Improves Insulin Sensitivity and Vascular Health in Youth With Type 1 Diabetes Mellitus

(2018) Petter Bjornstad et al.   CIRCULATION

A more tubulocentric view of diabetic kidney disease

(2017) Letizia Zeni et al.   JOURNAL OF NEPHROLOGY

The pharmacological regulation of cellular mitophagy

(2017) Nikolaos D Georgakopoulos et al.   Nature Chemical Biology

AMPK: guardian of metabolism and mitochondrial homeostasis

(2017) Sébastien Herzig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1

(2017) Li Xiao et al.   Redox Biology

AMPKα2 Protects Against the Development of Heart Failure by Enhancing Mitophagy via PINK1 Phosphorylation

(2017) Bei Wang et al.   CIRCULATION RESEARCH

Nephroprotective Effects of Metformin in Diabetic Nephropathy

(2016) Sreenithya Ravindran et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Trends in Chronic Kidney Disease in China

(2016) Luxia Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thioredoxin interacting protein (TXNIP) regulates tubular autophagy and mitophagy in diabetic nephropathy through the mTOR signaling pathway

(2016) Chunling Huang et al.   Scientific Reports

Impaired Podocyte Autophagy Exacerbates Proteinuria in Diabetic Nephropathy

(2015) Atsuko Tagawa et al.   DIABETES

Metformin prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction

(2015) Rita C. Cavaglieri et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

New developments concerning the proximal tubule in diabetic nephropathy:in vitromodels and mechanisms

(2015) Jennifer Slyne et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Reactive oxygen species and mitochondria: A nexus of cellular homeostasis

(2015) Joe Dan Dunn et al.   Redox Biology

The Concept and the Epidemiology of Diabetic Nephropathy Have Changed in Recent Years

(2015) Alberto Martínez-Castelao et al.   Journal of Clinical Medicine

Liraglutide inhibits autophagy and apoptosis induced by high glucose through GLP-1R in renal tubular epithelial cells

(2014) X ZHAO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Rap1 Ameliorates Renal Tubular Injury in Diabetic Nephropathy

(2013) L. Xiao et al.   DIABETES

Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation

(2012) Christine Juliana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy

(2011) Yashpal S. Kanwar et al.   Annual Review of Pathology-Mechanisms of Disease

Pathologic Classification of Diabetic Nephropathy

(2010) T. W. C. Tervaert et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY