The Human Nose Organoid Respiratory Virus Model: an Ex Vivo Human Challenge Model To Study Respiratory Syncytial Virus (RSV) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Pathogenesis and Evaluate Therapeutics

Viral load of SARS-CoV-2 in adults during the first and second wave of COVID-19 pandemic in Houston, TX: the potential of the super-spreader

(2021) Vasanthi Avadhanula et al.   JOURNAL OF INFECTIOUS DISEASES

Human Respiratory Syncytial Virus Subgroup A and B Infections in Nasal, Bronchial, Small-Airway, and Organoid-Derived Respiratory Cultures

(2021) L. C. Rijsbergen et al.   mSphere

An interactive web-based dashboard to track COVID-19 in real time

(2020) Ensheng Dong et al.   LANCET INFECTIOUS DISEASES

Structural and functional variations in human bronchial epithelial cells cultured in air-liquid interface using different growth media

(2020) Clarus Leung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Airway organoids as models of human disease

(2020) J. Vaart et al.   JOURNAL OF INTERNAL MEDICINE

SARS-CoV-2 productively infects human gut enterocytes

(2020) Mart M. Lamers et al.   SCIENCE

SARS-CoV-2 infects and damages the mature and immature olfactory sensory neurons of hamsters

(2020) Anna Jinxia Zhang et al.   CLINICAL INFECTIOUS DISEASES

Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

(2020) Brandi N. Williamson et al.   NATURE

SARS-CoV-2 is transmitted via contact and via the air between ferrets

(2020) Mathilde Richard et al.   Nature Communications

Distinct and early increase in circulating MMP-9 in COVID-19 patients with respiratory failure

(2020) T Ueland et al.   JOURNAL OF INFECTION

Animal and translational models of SARS-CoV-2 infection and COVID-19

(2020) M. D. Johansen et al.   Mucosal Immunology

An organoid‐derived bronchioalveolar model for SARS‐CoV‐2 infection of human alveolar type II‐like cells

(2020) Mart M Lamers et al.   EMBO JOURNAL

Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles

(2020) Akshamal M. Gamage et al.   PLoS Pathogens

Long‐term expanding human airway organoids for disease modeling

(2019) Norman Sachs et al.   EMBO JOURNAL

Development of a Novel ex vivo Nasal Epithelial Cell Model Supporting Colonization With Human Nasal Microbiota

(2019) Derald D. Charles et al.   Frontiers in Cellular and Infection Microbiology

Cytokines in the Respiratory Airway as Biomarkers of Severity and Prognosis for Respiratory Syncytial Virus Infection: An Update

(2019) Yaneisi Vázquez et al.   Frontiers in Immunology

Detection of CFTR function and modulation in primary human nasal cell spheroids

(2018) John J. Brewington et al.   Journal of Cystic Fibrosis

Comparison of Palivizumab-Like Antibody Binding to Different Conformations of the RSV F Protein in RSV-Infected Adult Hematopoietic Cell Transplant Recipients

(2018) Xunyan Ye et al.   JOURNAL OF INFECTIOUS DISEASES

Differentiated human airway organoids to assess infectivity of emerging influenza virus

(2018) Jie Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel Segment- and Host-Specific Patterns of Enteroaggregative Escherichia coli Adherence to Human Intestinal Enteroids

(2018) Anubama Rajan et al.   mBio

Respiratory syncytial virus fusion nanoparticle vaccine immune responses target multiple neutralizing epitopes that contribute to protection against wild-type and palivizumab-resistant mutant virus challenge

(2018) Brian E. Gilbert et al.   VACCINE

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

(2017) Ting Shi et al.   LANCET

Blood Biomarkers in Idiopathic Pulmonary Fibrosis

(2017) Julien Guiot et al.   LUNG

A three-dimensional model of human lung development and disease from pluripotent stem cells

(2017) Ya-Wen Chen et al.   NATURE CELL BIOLOGY

Animal models of respiratory syncytial virus infection

(2017) Geraldine Taylor   VACCINE

BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors

(2016) Tomomi Tadokoro et al.   DEVELOPMENT

Robust Cytokine and Chemokine Response in Nasopharyngeal Secretions: Association With Decreased Severity in Children With Physician Diagnosed Bronchiolitis

(2016) Erin G. Nicholson et al.   JOURNAL OF INFECTIOUS DISEASES

Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology

(2015) Kapil Saxena et al.   JOURNAL OF VIROLOGY

Matrix Metalloproteinase 9 Exerts Antiviral Activity against Respiratory Syncytial Virus

(2015) Abdoulaye J. Dabo et al.   PLoS One

In vitro generation of human pluripotent stem cell derived lung organoids

(2015) Briana R Dye et al.   eLife

Testing gene therapy vectors in human primary nasal epithelial cultures

(2015) Huibi Cao et al.   Molecular Therapy-Methods & Clinical Development

Infection With Novel Respiratory Syncytial Virus Genotype Ontario (ON1) in Adult Hematopoietic Cell Transplant Recipients, Texas, 2011-2013

(2014) V. Avadhanula et al.   JOURNAL OF INFECTIOUS DISEASES

Updated Guidance for Palivizumab Prophylaxis Among Infants and Young Children at Increased Risk of Hospitalization for Respiratory Syncytial Virus Infection

(2014)   PEDIATRICS

Respiratory Syncytial Virus Can Infect Basal Cells and Alter Human Airway Epithelial Differentiation

(2014) B. David Persson et al.   PLoS One

IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells

(2014) T. Tadokoro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient generation of lung and airway epithelial cells from human pluripotent stem cells

(2013) Sarah X L Huang et al.   NATURE BIOTECHNOLOGY

Culturing of Human Nasal Epithelial Cells at the Air Liquid Interface

(2013) Loretta Müller et al.   Jove-Journal of Visualized Experiments

In vitro modeling of respiratory syncytial virus infection of pediatric bronchial epithelium, the primary target of infection in vivo

(2012) R. Villenave et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal models of human respiratory syncytial virus disease

(2011) Reinout A. Bem et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

(2010) Harish Nair et al.   LANCET