4′,7-Di-O-methylnaringenin (DMNG), a naringenin derivative, activates p53 signal pathway through down-regulating MDM2

MDM2 inhibition: an important step forward in cancer therapy

(2020) Marina Konopleva et al.   LEUKEMIA

Targeting p53 for the treatment of cancer

(2020) Michael J. Duffy et al.   SEMINARS IN CANCER BIOLOGY

Anti‐inflammatory and anticancer activities of Naringenin‐loaded liquid crystalline nanoparticles in vitro

(2020) Ridhima Wadhwa et al.   JOURNAL OF FOOD BIOCHEMISTRY

Naringin and naringenin as anticancer agents and adjuvants in cancer combination therapy: Efficacy and molecular mechanisms of action, a comprehensive narrative review

(2020) Zahra Memariani et al.   PHARMACOLOGICAL RESEARCH

p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition

(2019) Monika Aggarwal et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

BCL-2 proteins and apoptosis: Recent insights and unknowns

(2018) Frank Edlich   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Augmented antitumor activity of 5-fluorouracil by double knockdown of MDM4 and MDM2 in colon and gastric cancer cells

(2018) Mamiko Imanishi et al.   CANCER SCIENCE

Naringenin-Induced Apoptotic Cell Death in Prostate Cancer Cells Is Mediated via the PI3K/AKT and MAPK Signaling Pathways

(2017) Whasun Lim et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Naringenin-Mediated ATF3 Expression Contributes to Apoptosis in Human Colon Cancer

(2016) Hun Min Song et al.   Biomolecules & Therapeutics

Naringenin targets ERK2 and suppresses UVB-induced photoaging

(2016) Sung Keun Jung et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

p53 in the DNA-Damage-Repair Process

(2016) Ashley B. Williams et al.   Cold Spring Harbor Perspectives in Medicine

Microbial and Natural Metabolites That Inhibit Splicing: A Powerful Alternative for Cancer Treatment

(2016) Nancy Martínez-Montiel et al.   Biomed Research International

The nucleolus as a fundamental regulator of the p53 response and a new target for cancer therapy

(2015) Simone J. Woods et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Enhanced anticancer effect of ABT-737 in combination with naringenin on gastric cancer cells

(2015) HAIYANG ZHANG et al.   Experimental and Therapeutic Medicine

The regulation of MDM2 oncogene and its impact on human cancers

(2014) Y. Zhao et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Naringenin inhibits migration of bladder cancer cells through downregulation of AKT and MMP-2

(2014) ALEX CHIEN HWA LIAO et al.   Molecular Medicine Reports

The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a

(2013) A Sparks et al.   ONCOGENE

Triptolide Inhibits MDM2 and Induces Apoptosis in Acute Lymphoblastic Leukemia Cells through a p53-Independent Pathway

(2012) M. Huang et al.   MOLECULAR CANCER THERAPEUTICS

A Synthetic Naringenin Derivative, 5-Hydroxy-7,4′-diacetyloxyflavanone-N-phenyl Hydrazone (N101-43), Induces Apoptosis through Up-regulation of Fas/FasL Expression and Inhibition of PI3K/Akt Signaling Pathways in Non-Small-Cell Lung Cancer Cells

(2011) Yesol Bak et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The p53-, Bax- and p21-dependent inhibition of colon cancer cell growth by 5-hydroxy polymethoxyflavones

(2010) Peiju Qiu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Naringenin up-regulates the expression of death receptor 5 and enhances TRAIL-induced apoptosis in human lung cancer A549 cells

(2010) Cheng-Yun Jin et al.   MOLECULAR NUTRITION & FOOD RESEARCH

p53 Research: The Past Thirty Years and the Next Thirty Years

(2010) D. Lane et al.   Cold Spring Harbor Perspectives in Biology

Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions

(2009) Y.N. V. Gopal et al.   MOLECULAR CANCER THERAPEUTICS

Murine double minute 2: p53-independent roads lead to genome instability or death

(2009) Alyssa Bouska et al.   TRENDS IN BIOCHEMICAL SCIENCES

Naringenin Enhances the Anti-Tumor Effect of Doxorubicin Through Selectively Inhibiting the Activity of Multidrug Resistance-Associated Proteins but not P-glycoprotein

(2008) Fa Yun Zhang et al.   PHARMACEUTICAL RESEARCH

Regulation of apoptosis by modified naringenin derivatives in human colorectal carcinoma RKO cells

(2007) Eung-Ryoung Lee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY