Inhibiting effects of polyphenols on angiogenesis and epithelial-mesenchymal transition in anterior segment eye diseases

Matrix Metalloproteinases and Glaucoma Treatment

(2020) Robert N. Weinreb et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Topical Application of Hyaluronic Acid-RGD Peptide-Coated Gelatin/Epigallocatechin-3 Gallate (EGCG) Nanoparticles Inhibits Corneal Neovascularization via Inhibition of VEGF Production

(2020) Takuya Miyagawa et al.   Pharmaceutics

ERK and Akt exhibit distinct signaling responses following stimulation by pro-angiogenic factors

(2020) Min Song et al.   Cell Communication and Signaling

EMT and EndMT: Emerging Roles in Age-Related Macular Degeneration

(2020) Daisy Y. Shu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Review of proteomics approach to eye diseases affecting the anterior segment

(2020) Hossein Aghamollaei et al.   Journal of Proteomics

Tetrahydrocurcumin mitigates acute hypobaric hypoxia‐induced cerebral oedema and inflammation through the NF‐κB / VEGF / MMP ‐9 pathway

(2020) Yang Pan et al.   PHYTOTHERAPY RESEARCH

Role of oxidative stress and vascular endothelial growth factor expression in pterygium pathogenesis and prevention of pterygium recurrence after surgical excision

(2020) Sameh Mohamed Elgouhary et al.   INTERNATIONAL OPHTHALMOLOGY

Depot formulations to sustain periocular drug delivery to the posterior eye segment

(2019) Yosra Agban et al.   DRUG DISCOVERY TODAY

Topical administration of a ROCK inhibitor prevents anterior subcapsular cataract induced by UV-B irradiation

(2019) Toshiyasu Imaizumi et al.   EXPERIMENTAL EYE RESEARCH

Cucurbita argyrosperma Seed Extracts Attenuate Angiogenesis in a Corneal Chemical Burn Model

(2019) María Fernanda Estrella-Mendoza et al.   Nutrients

Nutritional Strategies to Prevent Lens Cataract: Current Status and Future Strategies

(2019) Andrea J Braakhuis et al.   Nutrients

Gremlin is a potential target for posterior capsular opacification

(2019) Bo Ma et al.   CELL CYCLE

Potential Therapeutic Agents, Polymethoxylated Flavones Isolated from Kaempferia parviflora for Cataract Prevention through Inhibition of Matrix Metalloproteinase-9 in Lens Epithelial Cells

(2019) Yoshiki Miyata et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Reduction of metastatic potential by inhibiting EGFR/Akt/p38/ERK signaling pathway and epithelial-mesenchymal transition after carbon ion exposure is potentiated by PARP-1 inhibition in non-small-cell lung cancer

(2019) Priyanka Chowdhury et al.   BMC CANCER

Development of Kaempferol-Loaded Gelatin Nanoparticles for the Treatment of Corneal Neovascularization in Mice

(2019) Yu-Lun Chuang et al.   Pharmaceutics

Flavonoid fisetin alleviates kidney inflammation and apoptosis via inhibiting Src-mediated NF-κB p65 and MAPK signaling pathways in septic AKI mice

(2019) Qian Ren et al.   BIOMEDICINE & PHARMACOTHERAPY

HSP90 as a novel therapeutic target for posterior capsule opacification

(2019) Jing Li et al.   EXPERIMENTAL EYE RESEARCH

Selective IKK2 inhibitor IMD0354 disrupts NF-κB signaling to suppress corneal inflammation and angiogenesis

(2018) Anton Lennikov et al.   ANGIOGENESIS

Nepetin inhibits IL-1β induced inflammation via NF-κB and MAPKs signaling pathways in ARPE-19 cells

(2018) Xi Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

7,8,3′-Trihydroxyflavone ameliorate oxidative stress in vivo and promotes neurite regeneration in vitro in rat retinal ganglion cells

(2018) Wei Han et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Corneal lymphangiogenesis facilitates ocular surface inflammation and cell trafficking in dry eye disease

(2018) Yong Woo Ji et al.   Ocular Surface

Prevalence and risk factors of pterygium: a systematic review and meta-analysis

(2018) Farhad Rezvan et al.   SURVEY OF OPHTHALMOLOGY

Ocular Drug Delivery Barriers—Role of Nanocarriers in the Treatment of Anterior Segment Ocular Diseases

(2018) Rinda Bachu et al.   Pharmaceutics

IOP lowering effect of topical trans-resveratrol involves adenosine receptors and TGF-β2 signaling pathways

(2018) Norhafiza Razali et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

(-)-Epigallocatechin-3-gallate, reduces corneal damage secondary from experimental grade II alkali burns in mice

(2018) Rosario Gulias-Cañizo et al.   BURNS

Overview of polyphenols and polyphenol-rich extracts as modulators of IGF-1, IGF-1R, and IGFBP expression in cancer diseases

(2018) Miłosz Caban et al.   Journal of Functional Foods

Effect of Resveratrol, a Dietary-Derived Polyphenol, on the Oxidative Stress and Polyol Pathway in the Lens of Rats with Streptozotocin-Induced Diabetes

(2018) Lech Sedlak et al.   Nutrients

Inhibitory effects of rosmarinic acid on pterygium epithelial cells through redox imbalance and induction of extrinsic and intrinsic apoptosis

(2017) Ya-Yu Chen et al.   EXPERIMENTAL EYE RESEARCH

Efficacy of curcumin in inducing apoptosis and inhibiting the expression of VEGF in human pterygium fibroblasts

(2017) Cheng-Wei Lu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Fibroblast growth factor-2 drives and maintains progressive corneal neovascularization following HSV-1 infection

(2017) H R Gurung et al.   Mucosal Immunology

TFOS DEWS II pathophysiology report

(2017) Anthony J. Bron et al.   Ocular Surface

Inhibition of nuclear factor-kappaB, cyclooxygenase-2, and metalloproteinase-9 expression by flavanols from evening primrose ( Oenothera paradoxa ) in human colon cancer SW-480 cells

(2017) Katarzyna Owczarek et al.   Journal of Functional Foods

Inhibiting effects of dietary polyphenols on chronic eye diseases

(2017) Zhihan Xu et al.   Journal of Functional Foods

Magnitude, temporal trends, and projections of the global prevalence of blindness and distance and near vision impairment: a systematic review and meta-analysis

(2017) Rupert R A Bourne et al.   Lancet Global Health

Anti-angiogenic effect of hexahydrocurcumin in rat corneal neovascularization

(2017) Chien-Neng Kuo et al.   INTERNATIONAL OPHTHALMOLOGY

Both Autocrine Signaling and Paracrine Signaling of HB-EGF Enhance Ocular Neovascularization

(2017) Yuki Inoue et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Metalloproteinase 9 and TIMP-1 expression in retina and optic nerve in absolute angle closure glaucoma

(2016) Renata Zalewska et al.   Advances in Medical Sciences

Inhibition of VEGF mediated corneal neovascularization by anti-angiogenic peptide nanofibers

(2016) Berna Senturk et al.   BIOMATERIALS

Topical trans-resveratrol ameliorates steroid-induced anterior and posterior segment changes in rats

(2016) Norhafiza Razali et al.   EXPERIMENTAL EYE RESEARCH

Fibrosis in the lens. Sprouty regulation of TGFβ-signaling prevents lens EMT leading to cataract

(2016) F.J. Lovicu et al.   EXPERIMENTAL EYE RESEARCH

Conjunctival fibrosis following filtering glaucoma surgery

(2016) Günther Schlunck et al.   EXPERIMENTAL EYE RESEARCH

Preparation of arginine–glycine–aspartic acid-modified biopolymeric nanoparticles containing epigalloccatechin-3-gallate for targeting vascular endothelial cells to inhibit corneal neovascularization

(2016) Che-Yi Chang et al.   International Journal of Nanomedicine

The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults

(2016) Małgorzata Nita et al.   Oxidative Medicine and Cellular Longevity

Antioxidant-Rich Extract from Plantaginis Semen Ameliorates Diabetic Retinal Injury in a Streptozotocin-Induced Diabetic Rat Model

(2016) Thing-Fong Tzeng et al.   Nutrients

Role of EMT in Metastasis and Therapy Resistance

(2016) Bethany Smith et al.   Journal of Clinical Medicine

Synergistic Effect of Artificial Tears Containing Epigallocatechin Gallate and Hyaluronic Acid for the Treatment of Rabbits with Dry Eye Syndrome

(2016) Ching-Li Tseng et al.   PLoS One

Curcumin nanoparticles inhibit corneal neovascularization

(2015) Nirparaj Pradhan et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Effect of Topical Epigallocatechin Gallate on Corneal Neovascularization in Rabbits

(2014) Chang Hyun Koh et al.   CORNEA

Rosmarinic Acid Suppresses Subconjunctival Neovascularization in Experimental Glaucoma Surgery

(2014) Juliana de Lucena Martins Ferreira et al.   CURRENT EYE RESEARCH

Resveratrol and the eye: activity and molecular mechanisms

(2014) Christina Bola et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040

(2014) Yih-Chung Tham et al.   OPHTHALMOLOGY

Soyasaponins Can Blunt Inflammation by Inhibiting the Reactive Oxygen Species-Mediated Activation of PI3K/Akt/NF-kB Pathway

(2014) Longying Zha et al.   PLoS One

Secondary Analyses of the Effects of Lutein/Zeaxanthin on Age-Related Macular Degeneration Progression

(2014) Emily Y. Chew et al.   JAMA Ophthalmology

Vascular endothelial growth factor gene polymorphism and protein expression in the pathogenesis of pterygium

(2013) Mei-Ling Peng et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Progress in the Pathogenesis of Pterygium

(2013) Ting Liu et al.   CURRENT EYE RESEARCH

Anterior Eye Segment Drug Delivery Systems: Current Treatments and Future Challenges

(2013) Sarah A. Molokhia et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Evaluation of the effects of resveratrol and bevacizumab on experimental corneal alkali burn

(2012) Selim Doganay et al.   BURNS

Curcumin inhibits proliferation of human lens epithelial cells: a proteomic analysis

(2012) Yan-hong Hu et al.   Journal of Zhejiang University-SCIENCE B

Corneal Neovascularization: An Anti-VEGF Therapy Review

(2012) Jin-Hong Chang et al.   SURVEY OF OPHTHALMOLOGY

Global estimates of visual impairment: 2010

(2011) Donatella Pascolini et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Therapeutic Efficacy of Topical Epigallocatechin Gallate in Murine Dry Eye

(2011) Hyun Soo Lee et al.   CORNEA

Evidence of Corneal Lymphangiogenesis in Dry Eye Disease

(2010) Sunali Goyal   ARCHIVES OF OPHTHALMOLOGY

The Effect of Curcumin on Corneal Neovascularization in Rabbit Eyes

(2010) Jung Sub Kim et al.   CURRENT EYE RESEARCH

Curcumin protects against hyperosmoticity-induced IL-1β elevation in human corneal epithelial cell via MAPK pathways

(2009) Min Chen et al.   EXPERIMENTAL EYE RESEARCH

Posterior capsule opacification

(2008) I. Michael Wormstone et al.   EXPERIMENTAL EYE RESEARCH

Resveratrol prevents the expression of glaucoma markers induced by chronic oxidative stress in trabecular meshwork cells

(2008) Coralia Luna et al.   FOOD AND CHEMICAL TOXICOLOGY

Hydrocaffeic andp-coumaric acids, natural phenolic compounds, inhibit UV-B damage in WKD human conjunctival cellsin vitroand rabbit eyein vivo

(2008) Mar Larrosa et al.   FREE RADICAL RESEARCH

Inhibitory Effect of Curcumin on Corneal Neovascularization in vitro and in vivo

(2008) Fang Bian et al.   OPHTHALMOLOGICA