Induction of thymic atrophy and loss of thymic output by type-I interferons during chronic viral infection

Chronic viral infections persistently alter marrow stroma and impair hematopoietic stem cell fitness

(2021) Stephan Isringhausen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection

(2020) Heidi J. Elsaesser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type I interferon signaling attenuates regulatory T cell function in viral infection and in the tumor microenvironment

(2018) Arunakumar Gangaplara et al.   PLoS Pathogens

Type I Interferon Responses by HIV-1 Infection: Association with Disease Progression and Control

(2018) Andrew Soper et al.   Frontiers in Immunology

Irreversible splenic atrophy following chronic LCMV infection is associated with compromised immunity in mice

(2016) Achire N. Mbanwi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Impact of Viral Infections on Hematopoiesis: From Beneficial to Detrimental Effects on Bone Marrow Output

(2016) Maria Fernanda Pascutti et al.   Frontiers in Immunology

Blockade of Interferon Beta, but Not Interferon Alpha, Signaling Controls Persistent Viral Infection

(2015) Cherie T. Ng et al.   Cell Host & Microbe

Early Virus-Host Interactions Dictate the Course of a Persistent Infection

(2015) Brian M. Sullivan et al.   PLoS Pathogens

Modified interferon-α subtypes production and chemokine networks in the thymus during acute simian immunodeficiency virus infection, impact on thymopoiesis

(2014) Jacques Dutrieux et al.   AIDS

Reversible Blockade of Thymic Output: An Inherent Part of TLR Ligand-Mediated Immune Response

(2014) T. Demoulins et al.   JOURNAL OF IMMUNOLOGY

TLR Ligand-Induced Type I IFNs Affect Thymopoiesis

(2014) M.-L. Baron et al.   JOURNAL OF IMMUNOLOGY

Immune Responses to Hepatitis C Virus (HCV) Infection and the Prospects for an Effective HCV Vaccine or Immunotherapies

(2013) Georg M. Lauer   JOURNAL OF INFECTIOUS DISEASES

Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs

(2013) Christine Katlama et al.   LANCET

Blockade of Chronic Type I Interferon Signaling to Control Persistent LCMV Infection

(2013) E. B. Wilson et al.   SCIENCE

Persistent LCMV Infection Is Controlled by Blockade of Type I Interferon Signaling

(2013) J. R. Teijaro et al.   SCIENCE

Timing and Magnitude of Type I Interferon Responses by Distinct Sensors Impact CD8 T Cell Exhaustion and Chronic Viral Infection

(2012) Yaming Wang et al.   Cell Host & Microbe

Differential Roles for RIG-I-like Receptors and Nucleic Acid-Sensing TLR Pathways in Controlling a Chronic Viral Infection

(2012) J. M. Clingan et al.   JOURNAL OF IMMUNOLOGY

HIV-Associated Immune Activation: From Bench to Bedside

(2011) Gabriella d'Ettorre et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Prolonged Interleukin-2Rα Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo

(2010) Vandana Kalia et al.   IMMUNITY

IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells

(2009) M. A. Brockman et al.   BLOOD

Poly (I:C) induced immune response in lymphoid tissues involves three sequential waves of type I IFN expression

(2009) Thomas Démoulins et al.   VIROLOGY

Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

(2008) Surojit Sarkar et al.   JOURNAL OF EXPERIMENTAL MEDICINE