HIV-Associated Immune Activation: From Bench to Bedside

Cutting Edge: Experimentally Induced Immune Activation in Natural Hosts of Simian Immunodeficiency Virus Induces Significant Increases in Viral Replication and CD4+ T Cell Depletion

(2014) I. Pandrea et al.   JOURNAL OF IMMUNOLOGY

Pathogenic Mechanisms of HIV Disease

(2011) Susan Moir et al.   Annual Review of Pathology-Mechanisms of Disease

Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates

(2010) J. C. Engram et al.   BLOOD

Involvement of Regulatory T Cells in HIV Immunopathogenesis

(2010) Sara S. Bernardes et al.   CURRENT HIV RESEARCH

Nonprogressive and Progressive Primate Immunodeficiency Lentivirus Infections

(2010) Jason M. Brenchley et al.   IMMUNITY

Disruption of Intestinal CD4+ T Cell Homeostasis Is a Key Marker of Systemic CD4+ T Cell Activation in HIV-Infected Individuals

(2010) S. N. Gordon et al.   JOURNAL OF IMMUNOLOGY

The Virologic and Immunologic Effects of Cyclosporine as an Adjunct to Antiretroviral Therapy in Patients Treated during Acute and Early HIV‐1 Infection

(2010) Martin Markowitz et al.   JOURNAL OF INFECTIOUS DISEASES

Innate Immune Activation in Primary HIV‐1 Infection

(2010) J. Judy Chang et al.   JOURNAL OF INFECTIOUS DISEASES

Susceptibility of Human Th17 Cells to Human Immunodeficiency Virus and Their Perturbation during Infection

(2010) Aimee El Hed et al.   JOURNAL OF INFECTIOUS DISEASES

Reduction of Immune Activation with Chloroquine Therapy during Chronic HIV Infection

(2010) S. M. Murray et al.   JOURNAL OF VIROLOGY

HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects

(2010) Maria J Buzón et al.   NATURE MEDICINE

Therapeutic Immunization with HIV-1 Tat Reduces Immune Activation and Loss of Regulatory T-Cells and Improves Immune Function in Subjects on HAART

(2010) Barbara Ensoli et al.   PLoS One

First Report on a Series of HIV Patients Undergoing Rapamycin Monotherapy After Liver Transplantation

(2010) Fabrizio Di Benedetto et al.   TRANSPLANTATION

Impaired Toll-like receptor 7 and 9 signaling: from chronic viral infections to cancer

(2010) Ivan Hirsch et al.   TRENDS IN IMMUNOLOGY

Therapy for persistent HIV

(2010) Kara S. Keedy et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Th17 cells in pathogenic simian immunodeficiency virus infection of macaques

(2010) Valentina Cecchinato et al.   Current Opinion in HIV and AIDS

Th17 cells in natural SIV hosts

(2010) Mirko Paiardini   Current Opinion in HIV and AIDS

Th17, gut, and HIV: therapeutic implications

(2010) Peter W Hunt   Current Opinion in HIV and AIDS

Th17 lineage commitment and HIV-1 pathogenesis

(2010) Petronela Ancuta et al.   Current Opinion in HIV and AIDS

Th17 cells, HIV and the gut mucosal barrier

(2010) Satya Dandekar et al.   Current Opinion in HIV and AIDS

Biomarkers of immune dysfunction in HIV

(2010) Daniel E Nixon et al.   Current Opinion in HIV and AIDS

A Novel CCR5 Mutation Common in Sooty Mangabeys Reveals SIVsmm Infection of CCR5-Null Natural Hosts and Efficient Alternative Coreceptor Use In Vivo

(2010) Nadeene E. Riddick et al.   PLoS Pathogens

Where the Wild Things Are: Pathogenesis of SIV Infection in African Nonhuman Primate Hosts

(2010) Ivona Pandrea et al.   Current HIV/AIDS Reports

HIV-1 Tat dysregulation of lipopolysaccharide-induced cytokine responses: microbial interactions in HIV infection

(2009) Howard CH Yim et al.   AIDS

Lessons Learned from the Natural Hosts of HIV-Related Viruses

(2009) Mirko Paiardini et al.   Annual Review of Medicine

Current status and challenges of antiretroviral research and therapy

(2009) José A. Esté et al.   ANTIVIRAL RESEARCH

HIV reservoirs, latency, and reactivation: Prospects for eradication

(2009) Viktor Dahl et al.   ANTIVIRAL RESEARCH

AIDS in African Nonhuman Primate Hosts of SIVs: A New Paradigm of SIV Infection

(2009) Ivona Pandrea et al.   CURRENT HIV RESEARCH

Acyclovir: a new use for an old drug

(2009) Christophe Vanpouille et al.   CURRENT OPINION IN INFECTIOUS DISEASES

The Gastrointestinal Tract and AIDS Pathogenesis

(2009) Andrew A. Lackner et al.   GASTROENTEROLOGY

Premature Aging of T cells Is Associated With Faster HIV-1 Disease Progression

(2009) Weiwei Cao et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Relative risk of death in the SMART study

(2009) Birgit Grund et al.   LANCET INFECTIOUS DISEASES

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

HIV-1 Residual Viremia Correlates with Persistent T-Cell Activation in Poor Immunological Responders to Combination Antiretroviral Therapy

(2009) Maud Mavigner et al.   PLoS One

Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy

(2009) J. B. Dinoso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune modulators and treatment interruption

(2009) Felipe García et al.   Current Opinion in HIV and AIDS

Critical Loss of the Balance between Th17 and T Regulatory Cell Populations in Pathogenic SIV Infection

(2009) David Favre et al.   PLoS Pathogens

Emerging Concepts in the Immunopathogenesis of AIDS

(2008) Daniel C. Douek et al.   Annual Review of Medicine

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

(2008) J. M. Brenchley et al.   BLOOD

Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells

(2008) A. Bosque et al.   BLOOD

25 years of HIV research on virology, virus restriction, immunopathogenesis, genes and vaccines

(2008) E. Scherer et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Pathogenic mechanisms of B-lymphocyte dysfunction in HIV disease

(2008) Susan Moir et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Persistence of HIV in Gut‐Associated Lymphoid Tissue despite Long‐Term Antiretroviral Therapy

(2008) Tae‐Wook Chun et al.   JOURNAL OF INFECTIOUS DISEASES

Immune reconstitution in the sigmoid colon after long-term HIV therapy

(2008) P M Sheth et al.   Mucosal Immunology

Effective CD4+ T-cell restoration in gut-associated lymphoid tissue of HIV-infected patients is associated with enhanced Th17 cells and polyfunctional HIV-specific T-cell responses

(2008) M Macal et al.   Mucosal Immunology

HIV infection-associated immune activation occurs by two distinct pathways that differentially affect CD4 and CD8 T cells

(2008) M. Catalfamo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory T Cells and HIV-1 Infection

(2008) Velislava Terzieva   VIRAL IMMUNOLOGY

Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection

(2008) Lewis H Kuller et al.   PLOS MEDICINE