Labyrinthopeptin A1 inhibits dengue and Zika virus infection by interfering with the viral phospholipid membrane

Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry

(2020) Sebastian Blockus et al.   ANTIVIRAL RESEARCH

Protein- and Peptide-Based Virus Inactivators: Inactivating Viruses Before Their Entry Into Cells

(2020) Xiaojie Su et al.   Frontiers in Microbiology

Membrane Lipid Composition: Effect on Membrane and Organelle Structure, Function and Compartmentalization and Therapeutic Avenues

(2019) Doralicia Casares et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Viral Polymerase Inhibitor Reduces Zika Virus Replication in the Reproductive Organs of Male Mice

(2019) Sofie Jacobs et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy

(2019) Vidyleison N. Camargos et al.   EBioMedicine

Labyrinthopeptins exert broad-spectrum antiviral activity through lipid-binding-mediated virolysis

(2019) Hans Prochnow et al.   JOURNAL OF VIROLOGY

Zika Virus Infection — After the Pandemic

(2019) Didier Musso et al.   NEW ENGLAND JOURNAL OF MEDICINE

Asian and African lineage Zika viruses show differential replication and innate immune responses in human dendritic cells and macrophages

(2019) Pamela Österlund et al.   Scientific Reports

The molecular tweezer CLR01 inhibits Ebola and Zika virus infection

(2018) Annika E. Röcker et al.   ANTIVIRAL RESEARCH

Zika virus as a sexually transmitted pathogen

(2018) Paul S. Mead et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Analysis of the immunological biomarker profile during acute Zika virus infection reveals the overexpression of CXCL10, a chemokine linked to neuronal damage

(2018) Felipe Gomes Naveca et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Comparative analysis of different cell systems for Zika virus (ZIKV) propagation and evaluation of anti-ZIKV compounds in vitro

(2018) Ilaria Vicenti et al.   VIRUS RESEARCH

The emergence of Zika virus and its new clinical syndromes

(2018) Theodore C. Pierson et al.   NATURE

Therapeutic treatment of Zika virus infection using a brain-penetrating antiviral peptide

(2018) Joshua A. Jackman et al.   NATURE MATERIALS

Targeting the Achilles Heel of Mosquito-Borne Viruses for Antiviral Therapy

(2018) Joshua A. Jackman et al.   ACS Infectious Diseases

Epigallocatechin gallate, an active green tea compound inhibits the Zika virus entry into host cells via binding the envelope protein

(2017) Nitin Sharma et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Zika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic Cells

(2017) James R. Bowen et al.   PLoS Pathogens

Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection

(2016) Avraham Bayer et al.   Cell Host & Microbe

Zika Virus Targets Different Primary Human Placental Cells, Suggesting Two Routes for Vertical Transmission

(2016) Takako Tabata et al.   Cell Host & Microbe

Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study

(2016) Van-Mai Cao-Lormeau et al.   LANCET

Zika Virus Associated with Microcephaly

(2016) Jernej Mlakar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zika virus impairs growth in human neurospheres and brain organoids

(2016) P. P. Garcez et al.   SCIENCE

Protective and immunological behavior of chimeric yellow fever dengue vaccine

(2016) Scott B. Halstead et al.   VACCINE

Virion-associated phosphatidylethanolamine promotes TIM1-mediated infection by Ebola, dengue, and West Nile viruses

(2015) Audrey Stéphanie Richard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flavivirus Entry Inhibitors

(2015) Qing-Yin Wang et al.   ACS Infectious Diseases

Sphingomyelin regulation of plasma membrane asymmetry, efflux and reverse cholesterol transport

(2014) Kailash Gulshan et al.   Clinical Lipidology

3′,5′Di-O-trityluridine inhibits in vitro flavivirus replication

(2013) Tine De Burghgraeve et al.   ANTIVIRAL RESEARCH

Heterologous Expression and Engineering Studies of Labyrinthopeptins, Class III Lantibiotics from Actinomadura namibiensis

(2013) Joanna M. Krawczyk et al.   CHEMISTRY & BIOLOGY

The Lantibiotic Peptide Labyrinthopeptin A1 Demonstrates Broad Anti-HIV and Anti-HSV Activity with Potential for Microbicidal Applications

(2013) Geoffrey Férir et al.   PLoS One

Flavivirus Entry Receptors: An Update

(2013) Manuel Perera-Lecoin et al.   Viruses-Basel

Sulfated Polysaccharide, Curdlan Sulfate, Efficiently Prevents Entry/Fusion and Restricts Antibody-Dependent Enhancement of Dengue Virus Infection In Vitro: A Possible Candidate for Clinical Application

(2013) Koji Ichiyama et al.   PLoS Neglected Tropical Diseases

Broad Antiviral Activity of Carbohydrate-Binding Agents against the Four Serotypes of Dengue Virus in Monocyte-Derived Dendritic Cells

(2011) Marijke M. F. Alen et al.   PLoS One

Labyrinthopeptins: A New Class of Carbacyclic Lantibiotics

(2010) Kathrin Meindl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Vitro Biosynthesis of the Prepeptide of Type-III Lantibiotic Labyrinthopeptin A2 Including Formation of a CC Bond as a Post-Translational Modification

(2010) Wolfgang M. Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Actinohivin, a Broadly Neutralizing Prokaryotic Lectin, Inhibits HIV-1 Infection by Specifically Targeting High-Mannose-Type Glycans on the gp120 Envelope

(2010) B. Hoorelbeke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antiviral activity of carbohydrate-binding agents and the role of DC-SIGN in dengue virus infection

(2009) Marijke M.F. Alen et al.   VIROLOGY