The emergence of Zika virus and its new clinical syndromes

Fetal Neuropathology in Zika Virus-Infected Pregnant Female Rhesus Monkeys

(2018) Amanda J. Martinot et al.   CELL

An Immunocompetent Mouse Model of Zika Virus Infection

(2018) Matthew J. Gorman et al.   Cell Host & Microbe

Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials

(2018) Martin R Gaudinski et al.   LANCET

Zika virus in French Polynesia 2013–14: anatomy of a completed outbreak

(2018) Didier Musso et al.   LANCET INFECTIOUS DISEASES

Therapeutic and protective efficacy of a dengue antibody against Zika infection in rhesus monkeys

(2018) Peter Abbink et al.   NATURE MEDICINE

Miscarriage and stillbirth following maternal Zika virus infection in nonhuman primates

(2018) Dawn M. Dudley et al.   NATURE MEDICINE

Zika Virus Shedding in Semen of Symptomatic Infected Men

(2018) Paul S. Mead et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chromosome 19 microRNAs exert antiviral activity independent from type III interferon signaling

(2018) Avraham Bayer et al.   PLACENTA

Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease

(2018) Qiang Ding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zika virus–related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice

(2018) Derek J. Platt et al.   Science Translational Medicine

Postnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques

(2018) Maud Mavigner et al.   Science Translational Medicine

Zika virus like particles elicit protective antibodies in mice

(2018) Mauricio A. Salvo et al.   PLoS Neglected Tropical Diseases

Zika virus infection in immunocompetent pregnant mice causes fetal damage and placental pathology in the absence of fetal infection

(2018) Frank M. Szaba et al.   PLoS Pathogens

Population-Based Surveillance of Birth Defects Potentially Related to Zika Virus Infection — 15 States and U.S. Territories, 2016

(2018) Augustina Delaney et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Acute Zika Virus Infection as a Risk Factor for Guillain-Barré Syndrome in Puerto Rico

(2017) Emilio Dirlikov et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Birth Defects Among Fetuses and Infants of US Women With Evidence of Possible Zika Virus Infection During Pregnancy

(2017) Margaret A. Honein et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Zika virus has oncolytic activity against glioblastoma stem cells

(2017) Zhe Zhu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Innate Immune Augmenting Vesicular Stomatitis Virus Expressing Zika Virus Proteins Confers Protective Immunity

(2017) Dillon Betancourt et al.   JOURNAL OF IMMUNOLOGY

Humoral Immune Responses Against Zika Virus Infection and the Importance of Preexisting Flavivirus Immunity

(2017) Lalita Priyamvada et al.   JOURNAL OF INFECTIOUS DISEASES

Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans

(2017) Alba Grifoni et al.   JOURNAL OF VIROLOGY

Bilateral posterior uveitis associated with Zika virus infection

(2017) Shilpa Kodati et al.   LANCET

Effect of acute Zika virus infection on sperm and virus clearance in body fluids: a prospective observational study

(2017) Guillaume Joguet et al.   LANCET INFECTIOUS DISEASES

Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes

(2017) Yang Liu et al.   NATURE

Zika virus evolution and spread in the Americas

(2017) Hayden C. Metsky et al.   NATURE

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

(2017) Norbert Pardi et al.   NATURE

A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models

(2017) Chao Shan et al.   NATURE MEDICINE

Structure of the immature Zika virus at 9 Å resolution

(2017) Vidya Mangala Prasad et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Safety and Immunogenicity of an Anti–Zika Virus DNA Vaccine — Preliminary Report

(2017) Pablo Tebas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Vulnerability of primitive human placental trophoblast to Zika virus

(2017) Megan A. Sheridan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses

(2017) Audrey Stéphanie Richard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurodevelopmental protein Musashi-1 interacts with the Zika genome and promotes viral replication

(2017) Pavithra L. Chavali et al.   SCIENCE

Enhancement of Zika virus pathogenesis by preexisting antiflavivirus immunity

(2017) Susana V. Bardina et al.   SCIENCE

A single mutation in the prM protein of Zika virus contributes to fetal microcephaly

(2017) Ling Yuan et al.   SCIENCE

Durability and correlates of vaccine protection against Zika virus in rhesus monkeys

(2017) Peter Abbink et al.   Science Translational Medicine

High Zika Virus Seroprevalence in Salvador, Northeastern Brazil Limits the Potential for Further Outbreaks

(2017) Eduardo Martins Netto et al.   mBio

Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes

(2017) Meghan S. Vermillion et al.   Nature Communications

Structure of the immature Zika virus at 9 Å resolution

(2017) Vidya Mangala Prasad et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human Zika infection induces a reduction of IFN-γ producing CD4 T-cells and a parallel expansion of effector Vδ2 T-cells

(2017) Eleonora Cimini et al.   Scientific Reports

Transcriptional Changes during Naturally Acquired Zika Virus Infection Render Dendritic Cells Highly Conducive to Viral Replication

(2017) Xiaoming Sun et al.   Cell Reports

Axl Mediates ZIKA Virus Entry in Human Glial Cells and Modulates Innate Immune Responses

(2017) Laurent Meertens et al.   Cell Reports

Flavivirus structural heterogeneity: implications for cell entry

(2017) Félix A Rey et al.   Current Opinion in Virology

Increased rates of Guillain-Barré syndrome associated with Zika virus outbreak in the Salvador metropolitan area, Brazil

(2017) Ashley R. Styczynski et al.   PLoS Neglected Tropical Diseases

Hydrocephalus and arthrogryposis in an immunocompetent mouse model of ZIKA teratogeny: A developmental study

(2017) Jose Xavier-Neto et al.   PLoS Neglected Tropical Diseases

Ontogeny of the B- and T-cell response in a primary Zika virus infection of a dengue-naïve individual during the 2016 outbreak in Miami, FL

(2017) Michael J. Ricciardi et al.   PLoS Neglected Tropical Diseases

A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses

(2017) Shashank Tripathi et al.   PLoS Pathogens

Impact of prior flavivirus immunity on Zika virus infection in rhesus macaques

(2017) Michael K. McCracken et al.   PLoS Pathogens

Zika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic Cells

(2017) James R. Bowen et al.   PLoS Pathogens

Analysis of the T Cell Response to Zika Virus and Identification of a Novel CD8+ T Cell Epitope in Immunocompetent Mice

(2017) Ryan D. Pardy et al.   PLoS Pathogens

Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques

(2017) Sydney M. Nguyen et al.   PLoS Pathogens

Pregnancy Outcomes After Maternal Zika Virus Infection During Pregnancy — U.S. Territories, January 1, 2016–April 25, 2017

(2017) Carrie K. Shapiro-Mendoza et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Health and Development at Age 19–24 Months of 19 Children Who Were Born with Microcephaly and Laboratory Evidence of Congenital Zika Virus Infection During the 2015 Zika Virus Outbreak — Brazil, 2017

(2017) Ashley Satterfield-Nash et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Antiviral CD8 T cells induce Zika-virus-associated paralysis in mice

(2017) Kellie A. Jurado et al.   Nature Microbiology

CD14+CD16+ monocytes are the main target of Zika virus infection in peripheral blood mononuclear cells in a paediatric study in Nicaragua

(2017) Daniela Michlmayr et al.   Nature Microbiology

Identification of Zika virus epitopes reveals immunodominant and protective roles for dengue virus cross-reactive CD8+ T cells

(2017) Jinsheng Wen et al.   Nature Microbiology

A Zika Vaccine Targeting NS1 Protein Protects Immunocompetent Adult Mice in a Lethal Challenge Model

(2017) Aaron C. Brault et al.   Scientific Reports

Characterization of a Novel Murine Model to Study Zika Virus

(2016) Shannan L. Rossi et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Zika virus: History, emergence, biology, and prospects for control

(2016) Scott C. Weaver et al.   ANTIVIRAL RESEARCH

Structural Basis of Zika Virus-Specific Antibody Protection

(2016) Haiyan Zhao et al.   CELL

Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise

(2016) Jonathan J. Miner et al.   CELL

Zika Virus Causes Testis Damage and Leads to Male Infertility in Mice

(2016) Wenqiang Ma et al.   CELL

Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection

(2016) Laura J. Yockey et al.   CELL

Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling

(2016) Alesha Grant et al.   Cell Host & Microbe

Zika Virus Infects Human Placental Macrophages

(2016) Kendra M. Quicke et al.   Cell Host & Microbe

Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection

(2016) Avraham Bayer et al.   Cell Host & Microbe

A Mouse Model of Zika Virus Pathogenesis

(2016) Helen M. Lazear et al.   Cell Host & Microbe

Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth

(2016) Hengli Tang et al.   Cell Stem Cell

Zika Virus Disrupts Neural Progenitor Development and Leads to Microcephaly in Mice

(2016) Cui Li et al.   Cell Stem Cell

Male-to-Female Sexual Transmission of Zika Virus—United States, January–April 2016

(2016) Kate Russell et al.   CLINICAL INFECTIOUS DISEASES

Zika virus inhibits type‐I interferon production and downstream signaling

(2016) Anil Kumar et al.   EMBO REPORTS

Dampened antiviral immunity to intravaginal exposure to RNA viral pathogens allows enhanced viral replication

(2016) Shahzada Khan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thrombocytopenia and subcutaneous bleedings in a patient with Zika virus infection

(2016) Ouafae Karimi et al.   LANCET

Pathology of congenital Zika syndrome in Brazil: a case series

(2016) Roosecelis Brasil Martines et al.   LANCET

Association between Zika virus and microcephaly in French Polynesia, 2013–15: a retrospective study

(2016) Simon Cauchemez et al.   LANCET

Zika virus in semen and spermatozoa

(2016) Jean Michel Mansuy et al.   LANCET INFECTIOUS DISEASES

Structure of the thermally stable Zika virus

(2016) Victor A. Kostyuchenko et al.   NATURE

Structural basis of potent Zika–dengue virus antibody cross-neutralization

(2016) Giovanna Barba-Spaeth et al.   NATURE

Vaccine protection against Zika virus from Brazil

(2016) Rafael A. Larocca et al.   NATURE

Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice

(2016) Gopal Sapparapu et al.   NATURE

The Brazilian Zika virus strain causes birth defects in experimental models

(2016) Fernanda R. Cugola et al.   NATURE

Zika virus infection damages the testes in mice

(2016) Jennifer Govero et al.   NATURE

Dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus

(2016) Wanwisa Dejnirattisai et al.   NATURE IMMUNOLOGY

Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate

(2016) Kristina M Adams Waldorf et al.   NATURE MEDICINE

Zika viral dynamics and shedding in rhesus and cynomolgus macaques

(2016) Christa E Osuna et al.   NATURE MEDICINE

The Neurobiology of Zika Virus

(2016) Hongda Li et al.   NEURON

Zika Virus Infection with Prolonged Maternal Viremia and Fetal Brain Abnormalities

(2016) Rita W. Driggers et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fatal Zika Virus Infection with Secondary Nonsexual Transmission

(2016) Sankar Swaminathan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zika Virus Infection in Pregnant Women in Rio de Janeiro

(2016) Patrícia Brasil et al.   NEW ENGLAND JOURNAL OF MEDICINE

Guillain–Barré Syndrome Associated with Zika Virus Infection in Colombia

(2016) Beatriz Parra et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zika Virus and the Guillain–Barré Syndrome — Case Series from Seven Countries

(2016) Thais dos Santos et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zika Virus Associated with Meningoencephalitis

(2016) Guillaume Carteaux et al.   NEW ENGLAND JOURNAL OF MEDICINE

Serologically Confirmed Zika-Related Unilateral Acute Maculopathy in an Adult

(2016) D. Wilkin Parke et al.   OPHTHALMOLOGY

Zika virus cell tropism in the developing human brain and inhibition by azithromycin

(2016) Hanna Retallack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus

(2016) Lalita Priyamvada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid development of a DNA vaccine for Zika virus

(2016) K. A. Dowd et al.   SCIENCE

Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys

(2016) P. Abbink et al.   SCIENCE

Zika virus in the Americas: Early epidemiological and genetic findings

(2016) N. R. Faria et al.   SCIENCE

The 3.8 A resolution cryo-EM structure of Zika virus

(2016) D. Sirohi et al.   SCIENCE

Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection

(2016) K. Stettler et al.   SCIENCE

Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus

(2016) Q. Wang et al.   Science Translational Medicine

Dengue Virus Envelope Dimer Epitope Monoclonal Antibodies Isolated from Dengue Patients Are Protective against Zika Virus

(2016) J. A. Swanstrom et al.   mBio

A rhesus macaque model of Asian-lineage Zika virus infection

(2016) Dawn M. Dudley et al.   Nature Communications

The IFITMs Inhibit Zika Virus Replication

(2016) George Savidis et al.   Cell Reports

Broadly Neutralizing Activity of Zika Virus-Immune Sera Identifies a Single Viral Serotype

(2016) Kimberly A. Dowd et al.   Cell Reports

Zika Virus Infection in Mice Causes Panuveitis with Shedding of Virus in Tears

(2016) Jonathan J. Miner et al.   Cell Reports

Zika Fetal Neuropathogenesis: Etiology of a Viral Syndrome

(2016) Zachary A. Klase et al.   PLoS Neglected Tropical Diseases

Full Genome Sequence and sfRNA Interferon Antagonist Activity of Zika Virus from Recife, Brazil

(2016) Claire L. Donald et al.   PLoS Neglected Tropical Diseases

Zika (PRVABC59) Infection Is Associated with T cell Infiltration and Neurodegeneration in CNS of Immunocompetent Neonatal C57Bl/6 Mice

(2016) Mohanraj Manangeeswaran et al.   PLoS Pathogens

Development of a Zika Virus Infection Model in Cynomolgus Macaques

(2016) Fusataka Koide et al.   Frontiers in Microbiology

Male-to-Male Sexual Transmission of Zika Virus — Texas, January 2016

(2016) D. Trew Deckard et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Characterization of a 2016 Clinical Isolate of Zika Virus in Non-human Primates

(2016) Xiao-Feng Li et al.   EBioMedicine

Recognition determinants of broadly neutralizing human antibodies against dengue viruses

(2015) Alexander Rouvinski et al.   NATURE

Zika virus infection complicated by Guillain-Barré syndrome – case report, French Polynesia, December 2013

(2014) E Oehler et al.   Eurosurveillance

Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells

(2013) D. Weiskopf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zika Virus Outbreak on Yap Island, Federated States of Micronesia

(2009) Mark R. Duffy et al.   NEW ENGLAND JOURNAL OF MEDICINE