Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage

VDAC Regulation of Mitochondrial Calcium Flux: From Channel Biophysics to Disease

(2021) William M. Rosencrans et al.   CELL CALCIUM

Lack of Evidence of ACE2 Expression and Replicative Infection by SARSCoV-2 in Human Endothelial Cells

(2021) Ian R. McCracken et al.   CIRCULATION

TLR9 and COVID-19: A Multidisciplinary Theory of a Multifaceted Therapeutic Target

(2021) Gillina F. G. Bezemer et al.   Frontiers in Pharmacology

Changes in mitochondrial morphology modulate LPS-induced loss of calcium homeostasis in BV-2 microglial cells

(2021) O. R. Pereira et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Endotheliitis, endothelin, and endothelin receptor blockers in COVID-19

(2021) Devang K. Sanghavi et al.   MEDICAL HYPOTHESES

Heparin prevents in vitro glycocalyx shedding induced by plasma from COVID-19 patients

(2021) Simone R. Potje et al.   LIFE SCIENCES

CD209L/L-SIGN and CD209/DC-SIGN Act as Receptors for SARS-CoV-2

(2021) Razie Amraei et al.   ACS Central Science

Is Low Alveolar Type II Cell SOD3 in the Lungs of Elderly Linked to the Observed Severity of COVID-19?

(2020) Ahmed S. Abouhashem et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial DNA in inflammation and immunity

(2020) Joel S Riley et al.   EMBO REPORTS

Post‐mortem examination of COVID19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction

(2020) T. Menter et al.   HISTOPATHOLOGY

Clinical and immunological features of severe and moderate coronavirus disease 2019

(2020) Guang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

In silico studies on the comparative characterization of the interactions of SARS‐CoV‐2 spike glycoprotein with ACE‐2 receptor homologs and human TLRs

(2020) Abhigyan Choudhury et al.   JOURNAL OF MEDICAL VIROLOGY

D‐dimer levels on admission to predict in‐hospital mortality in patients with Covid‐19

(2020) Litao Zhang et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Covid-19 accelerates endothelial dysfunction and nitric oxide deficiency

(2020) Shawn J. Green   MICROBES AND INFECTION

Multiorgan and Renal Tropism of SARS-CoV-2

(2020) Victor G. Puelles et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thrombosis in Hospitalized Patients With COVID-19 in a New York City Health System

(2020) Seda Bilaloglu et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

In vivo demonstration of microvascular thrombosis in severe COVID-19

(2020) Douglas Alexandre do Espírito Santo et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

A minimal common outcome measure set for COVID-19 clinical research

(2020) John C Marshall et al.   LANCET INFECTIOUS DISEASES

Extrapulmonary manifestations of COVID-19

(2020) Aakriti Gupta et al.   NATURE MEDICINE

Cellular Organelles Reorganization During Zika Virus Infection of Human Cells

(2020) Cybele C. García et al.   Frontiers in Microbiology

RNA-GPS Predicts SARS-CoV-2 RNA Residency to Host Mitochondria and Nucleolus

(2020) Kevin E. Wu et al.   Cell Systems

Venous Thromboembolism among Hospitalized Patients with COVID-19 Undergoing Thromboprophylaxis: A Systematic Review and Meta-Analysis

(2020) Gerald Chi et al.   Journal of Clinical Medicine

Intra-genome variability in the dinucleotide composition of SARS-CoV-2

(2020) Paul Digard et al.   Virus Evolution

Injury to the Endothelial Glycocalyx in Critically Ill Patients with COVID-19

(2020) Klaus Stahl et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

COVID-19 is, in the end, an endothelial disease

(2020) Peter Libby et al.   EUROPEAN HEART JOURNAL

Mitochondria: In the Cross Fire of SARS-CoV-2 and Immunity

(2020) Johannes Burtscher et al.   iScience

Tissue-Specific Immunopathology in Fatal COVID-19

(2020) David A. Dorward et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Low serum calcium: a new, important indicator of COVID-19 patients from mild/moderate to severe/critical

(2020) Xi Zhou et al.   BIOSCIENCE REPORTS

Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients

(2020) Tamara S. Rodrigues et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Endotheliitis bei COVID-19

(2020) Zsuzsanna Varga   PATHOLOGE

Mitochondrial DNA: A new driver for sex differences in spontaneous hypertension

(2019) Cinthya Echem et al.   PHARMACOLOGICAL RESEARCH

Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production

(2019) MengJie Hu et al.   eLife

Infection with the dengue RNA virus activates TLR9 signaling in human dendritic cells

(2018) Jenn‐Haung Lai et al.   EMBO REPORTS

Mitochondrial DNA damage and reactive oxygen species in neurodegenerative disease

(2018) Nadee Nissanka et al.   FEBS LETTERS

Potential contribution of mitochondrial DNA damage associated molecular patterns in transfusion products to the development of acute respiratory distress syndrome after multiple transfusions

(2017) Jon D. Simmons et al.   Journal of Trauma and Acute Care Surgery

Potential contribution of mitochondrial DNA damage associated molecular patterns in transfusion products to the development of acute respiratory distress syndrome after multiple transfusions

(2017) Jon D. Simmons et al.   Journal of Trauma and Acute Care Surgery

The role of TLR9 in stress-dependent autophagy formation

(2016) Jae Sung Lim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Accessory subunits are integral for assembly and function of human mitochondrial complex I

(2016) David A. Stroud et al.   NATURE

Mitochondrial diseases

(2016) Gráinne S. Gorman et al.   Nature Reviews Disease Primers

Circulating mitochondrial DNA and Toll-like receptor 9 are associated with vascular dysfunction in spontaneously hypertensive rats

(2015) Cameron G. McCarthy et al.   CARDIOVASCULAR RESEARCH

Toll-like receptor 9 protects non-immune cells from stress by modulating mitochondrial ATP synthesis through the inhibition of SERCA2

(2014) Y. Shintani et al.   EMBO REPORTS

SARS-Coronavirus Open Reading Frame-9b Suppresses Innate Immunity by Targeting Mitochondria and the MAVS/TRAF3/TRAF6 Signalosome

(2014) Chong-Shan Shi et al.   JOURNAL OF IMMUNOLOGY

TLR9 mediates cellular protection by modulating energy metabolism in cardiomyocytes and neurons

(2013) Y. Shintani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Viral calciomics: Interplays between Ca2+ and virus

(2009) Yubin Zhou et al.   CELL CALCIUM

Mitochondrial Respiratory Complex I: Structure, Function and Implication in Human Diseases

(2009) Lokendra Sharma et al.   CURRENT MEDICINAL CHEMISTRY

A CaPful of mechanisms regulating the mitochondrial permeability transition

(2009) Fabio Di Lisa et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY