Evaluation of human relevance of Nicofluprole-induced rat thyroid disruption

A review of species differences in the control of, and response to, chemical-induced thyroid hormone perturbations leading to thyroid cancer

(2021) John R. Foster et al.   ARCHIVES OF TOXICOLOGY

Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches

(2019) Pamela D. Noyes et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Comparison of the hepatic and thyroid gland effects of sodium phenobarbital and pregnenolone-16α-carbonitrile in wild-type and constitutive androstane receptor (CAR)/pregnane X receptor (PXR) knockout rats

(2018) Corinne Haines et al.   XENOBIOTICA

Human relevance of follicular thyroid tumors in rodents caused by non-genotoxic substances

(2018) Ruediger Bartsch et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Approaches for grouping of pesticides into cumulative assessment groups for risk assessment of pesticide residues in food

(2017) Thomas Colnot et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

A systematic evaluation of sorting motifs in the sodium-iodide symporter (NIS)

(2016) E. Darrouzet et al.   BIOCHEMICAL JOURNAL

Effects of β-Naphthoflavone on Ugt1a6 and Ugt1a7 Expression in Rat Brain

(2016) Yukiko Sakakibara et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Transactivation Assays to Assess Canine and Rodent Pregnane X Receptor (PXR) and Constitutive Androstane Receptor (CAR) Activation

(2016) Marija Pinne et al.   PLoS One

Drug-induced cholestasis detection in cryopreserved rat hepatocytes in sandwich culture

(2015) Marlies Oorts et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

The Acute Inhibitory Effect of Iodide Excess on Sodium/Iodide Symporter Expression and Activity Involves the PI3K/Akt Signaling Pathway

(2014) Caroline Serrano-Nascimento et al.   ENDOCRINOLOGY

Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence

(2014) M. E. Bette Meek et al.   JOURNAL OF APPLIED TOXICOLOGY

The sodium/iodide symporter: State of the art of its molecular characterization

(2013) Elisabeth Darrouzet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

New developments in the evolution and application of the WHO/IPCS framework on mode of action/species concordance analysis

(2013) M. E. Meek et al.   JOURNAL OF APPLIED TOXICOLOGY

In vitrometabolism of thyroxine by rat and human hepatocytes

(2013) Vicki M. Richardson et al.   XENOBIOTICA

PHASE II DRUG METABOLIZING ENZYMES

(2012) Petra Jancova et al.   BIOMEDICAL PAPERS-OLOMOUC

Plateable cryopreserved human hepatocytes for the assessment of cytochrome P450 inducibility: experimental condition-related variables affecting their response to inducers

(2012) Eliane Alexandre et al.   XENOBIOTICA

A novel role for AMP-kinase in the regulation of the Na+/I−-symporter and iodide uptake in the rat thyroid gland

(2011) Bruno M. Andrade et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Induction of Mouse UDP-Glucuronosyltransferase mRNA Expression in Liver and Intestine by Activators of Aryl-Hydrocarbon Receptor, Constitutive Androstane Receptor, Pregnane X Receptor, Peroxisome Proliferator-Activated Receptor  , and Nuclear Factor Erythroid 2-Related Factor 2

(2009) D. B. Buckley et al.   DRUG METABOLISM AND DISPOSITION

The regulation of UDP-glucuronosyltransferase genes by tissue-specific and ligand-activated transcription factors

(2009) Peter I. Mackenzie et al.   DRUG METABOLISM REVIEWS

Phase I to II cross-induction of xenobiotic metabolizing enzymes: A feedforward control mechanism for potential hormetic responses

(2009) Qiang Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Regulation of Sulfotransferase and UDP-Glucuronosyltransferase Gene Expression by the PPARs

(2009) Melissa Runge-Morris et al.   PPAR Research

Effects of Andrographis paniculata extract and Andrographolide on hepatic cytochrome P450 mRNA expression and monooxygenase activities after in vivo administration to rats and in vitro in rat and human hepatocyte cultures

(2008) Dumrongsak Pekthong et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Characterization of small-molecule inhibitors of the sodium iodide symporter

(2008) Sabine Lindenthal et al.   JOURNAL OF ENDOCRINOLOGY

Use of mRNA expression to detect the induction of drug metabolising enzymes in rat and human hepatocytes

(2008) L. Richert et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells

(2007) P Martin et al.   BRITISH JOURNAL OF PHARMACOLOGY