Exploring Pleiotropic Effects of Lipid Modifiers and Targets on Measures of the Coagulation System with Genetics

The use of two-sample methods for Mendelian randomization analyses on single large datasets

(2021) Cosetta Minelli et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Rosuvastatin use increases plasma fibrinolytic potential: a randomised clinical trial

(2020) Suzanne Schol‐Gelok et al.   BRITISH JOURNAL OF HAEMATOLOGY

Differential Effects of Testosterone on Peripheral Neutrophils, Monocytes and Platelets in Men: Findings from Two Trials

(2020) Thiago Gagliano-Jucá et al.   Andrology

A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling

(2020) Benjamin A.T. Rodriguez et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Chromosomal alterations among age-related haematopoietic clones in Japan

(2020) Chikashi Terao et al.   NATURE

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

(2020) Kazuyoshi Ishigaki et al.   NATURE GENETICS

Investigating pleiotropic effects of statins on ischemic heart disease in the UK Biobank using Mendelian randomisation

(2020) CM Schooling et al.   eLife

Predicting the effect of statins on cancer risk using genetic variants from a Mendelian randomization study in the UK Biobank

(2020) Paul Carter et al.   eLife

Mendelian Randomization Study of ACLY and Cardiovascular Disease

(2019) Brian A. Ference et al.   NEW ENGLAND JOURNAL OF MEDICINE

Advances in understanding the molecular mechanisms that maintain normal haemostasis

(2019) James S. O'Donnell et al.   BRITISH JOURNAL OF HAEMATOLOGY

Statins significantly reduce mortality in patients receiving clopidogrel without affecting platelet activation and aggregation: a systematic review and meta-analysis

(2019) Ke An et al.   Lipids in Health and Disease

From multi-target anticoagulants to DOACs, and intrinsic coagulation factor inhibitors

(2019) Lisha Lin et al.   BLOOD REVIEWS

Operating characteristics of the rank‐based inverse normal transformation for quantitative trait analysis in genome‐wide association studies

(2019) Zachary R. McCaw et al.   BIOMETRICS

Improvement of endothelial function by pitavastatin: a meta-analysis

(2018) Niki Katsiki et al.   EXPERT OPINION ON PHARMACOTHERAPY

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases

(2018) Masahiro Kanai et al.   NATURE GENETICS

Genetically Determined Platelet Count and Risk of Cardiovascular Disease

(2018) Dipender Gill et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Rosuvastatin use reduces thrombin generation potential in patients with venous thromboembolism: a randomized controlled trial

(2018) Fernanda A. Orsi et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Overview of the BioBank Japan Project: Study design and profile

(2017) Akiko Nagai et al.   JOURNAL OF EPIDEMIOLOGY

Specifying a target trial prevents immortal time bias and other self-inflicted injuries in observational analyses

(2016) Miguel A. Hernán et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Effects of add-on lipid-modifying therapy on top of background statin treatment on major cardiovascular events: A meta-analysis of randomized controlled trials

(2015) Chi-kin Ip et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Gene polymorphism and frequencies of theNPC1L1Gene (rs2072183, rs217434 and rs217428) in Japanese patients with dyslipidemia

(2014) Y. Kashiwabara et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Power and sample size calculations for Mendelian randomization studies using one genetic instrument

(2013) G. Freeman et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Effect of Simvastatin on Hemostasis in Patients with Isolated Hypertriglyceridemia

(2013) Robert Krysiak et al.   PHARMACOLOGY

Statins but Not Aspirin Reduce Thrombotic Risk Assessed by Thrombin Generation in Diabetic Patients without Cardiovascular Events: The RATIONAL Trial

(2012) Alejandro Macchia et al.   PLoS One

The effect of ezetimibe and simvastatin on hemostasis in patients with isolated hypercholesterolemia

(2011) Robert Krysiak et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Atorvastatin has antithrombotic effects in patients with type 1 diabetes and dyslipidemia

(2010) Sara Tehrani et al.   THROMBOSIS RESEARCH

Pleiotropic Effects and Cholesterol-Lowering Therapy

(2008) Steven M. Shaw et al.   CARDIOLOGY

Simvastatin Reduces Circulating Plasminogen Activator Inhibitor 1 Activity in Volunteers with the Metabolic Syndrome

(2008) Long Wang et al.   Metabolic Syndrome and Related Disorders