Tau-driven degeneration of sleep- and wake-regulating neurons in Alzheimer’s disease

A common hub for sleep and motor control in the substantia nigra

(2020) Danqian Liu et al.   SCIENCE

Locus coeruleus pathology in progressive supranuclear palsy, and its relation to disease severity

(2020) Sanne Simone Kaalund et al.   Acta Neuropathologica Communications

Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals

(2020) Satvinder Kaur et al.   Nature Communications

Glymphatic failure as a final common pathway to dementia

(2020) Maiken Nedergaard et al.   SCIENCE

Alpha‐frequency synchronization deficits during life predict postmortem neurofibrillary tangle burden in Alzheimer’s disease

(2020) Kamalini G Ranasinghe et al.   Alzheimers & Dementia

Reduced non–rapid eye movement sleep is associated with tau pathology in early Alzheimer’s disease

(2019) Brendan P. Lucey et al.   Science Translational Medicine

Control of Non-REM Sleep by Midbrain Neurotensinergic Neurons

(2019) Peng Zhong et al.   NEURON

Bidirectional relationship between sleep and Alzheimer’s disease: role of amyloid, tau, and other factors

(2019) Chanung Wang et al.   NEUROPSYCHOPHARMACOLOGY

Selective Vulnerability of the Nucleus Basalis of Meynert Among Neuropathologic Subtypes of Alzheimer Disease

(2019) Fadi S. Hanna Al-Shaikh et al.   JAMA Neurology

Tau seeding activity begins in the transentorhinal/entorhinal regions and anticipates phospho-tau pathology in Alzheimer’s disease and PART

(2018) Sarah K. Kaufman et al.   ACTA NEUROPATHOLOGICA

Selective Vulnerability of Brainstem Nuclei in Distinct Tauopathies: A Postmortem Study

(2018) Rana A Eser et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Characteristics of sleep-active neurons in the medullary parafacial zone in rats

(2018) Md Aftab Alam et al.   SLEEP

The role of sleep in regulating structural plasticity and synaptic strength: Implications for memory and cognitive function

(2018) Frank Raven et al.   SLEEP MEDICINE REVIEWS

Characteristics of sleep-active neurons in the medullary parafacial zone in rats

(2018) Md Aftab Alam et al.   SLEEP

Neuropathologic Correlates of Psychiatric Symptoms in Alzheimer’s Disease

(2018) Alexander J. Ehrenberg et al.   JOURNAL OF ALZHEIMERS DISEASE

Sleep and Wakefulness Are Controlled by Ventral Medial Midbrain/Pons GABAergic Neurons in Mice

(2018) Yohko Takata et al.   JOURNAL OF NEUROSCIENCE

The role of co-neurotransmitters in sleep and wake regulation

(2018) Jun Oh et al.   MOLECULAR PSYCHIATRY

GABA and glutamate neurons in the VTA regulate sleep and wakefulness

(2018) Xiao Yu et al.   NATURE NEUROSCIENCE

Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice

(2018) Daniel Kroeger et al.   Nature Communications

Alzheimer’s Disease: Characterization of the Brain Sites of the Initial Tau Cytoskeletal Pathology Will Improve the Success of Novel Immunological Anti-Tau Treatment Approaches

(2017) Udo Rüb et al.   JOURNAL OF ALZHEIMERS DISEASE

Hypothalamic Tuberomammillary Nucleus Neurons: Electrophysiological Diversity and Essential Role in Arousal Stability

(2017) Akie Fujita et al.   JOURNAL OF NEUROSCIENCE

Dysfunction of GABAergic neurons in the parafacial zone mediates sleep disturbances in a streptozotocin-induced rat model of sporadic Alzheimer’s disease

(2017) Jin-Zhi Song et al.   METABOLIC BRAIN DISEASE

Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep

(2017) Kai Liu et al.   NATURE

A Genetically Defined Circuit for Arousal from Sleep during Hypercapnia

(2017) Satvinder Kaur et al.   NEURON

Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer's disease

(2017) A. J. Ehrenberg et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Sleepless Night and Day, the Plight of Progressive Supranuclear Palsy

(2017) Christine M Walsh et al.   SLEEP

Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer’s disease

(2017) Annalisa Nobili et al.   Nature Communications

Sleepless Night and Day, the Plight of Progressive Supranuclear Palsy

(2017) Christine M Walsh et al.   SLEEP

Short or Long Sleep Duration Is Associated with Memory Impairment in Older Chinese: the Guangzhou Biobank Cohort Study

(2017) Lin Xu et al.   SLEEP

Evidence that Neurons of the Sublaterodorsal Tegmental Nucleus Triggering Paradoxical (REM) Sleep Are Glutamatergic

(2017) Olivier Clément et al.   SLEEP

Dopaminergic Neurons and Brain Reward Pathways

(2016) Sarah X. Luo et al.   AMERICAN JOURNAL OF PATHOLOGY

Cholinergic, Glutamatergic, and GABAergic Neurons of the Pedunculopontine Tegmental Nucleus Have Distinct Effects on Sleep/Wake Behavior in Mice

(2016) Daniel Kroeger et al.   JOURNAL OF NEUROSCIENCE

VTA dopaminergic neurons regulate ethologically relevant sleep–wake behaviors

(2016) Ada Eban-Rothschild et al.   NATURE NEUROSCIENCE

Progressive Loss of the Orexin Neurons Reveals Dual Effects on Wakefulness

(2016) Abigail F. Branch et al.   SLEEP

Sleep function: Toward elucidating an enigma

(2016) James M. Krueger et al.   SLEEP MEDICINE REVIEWS

Progressive Loss of the Orexin Neurons Reveals Dual Effects on Wakefulness

(2016) Abigail F. Branch et al.   SLEEP

Precortical Phase of Alzheimer's Disease (AD)-Related Tau Cytoskeletal Pathology

(2015) Katharina Stratmann et al.   BRAIN PATHOLOGY

Optogenetic Evidence for Inhibitory Signaling from Orexin to MCH Neurons via Local Microcircuits

(2015) J. Apergis-Schoute et al.   JOURNAL OF NEUROSCIENCE

Increased fragmentation of sleep–wake cycles in the 5XFAD mouse model of Alzheimer’s disease

(2015) M. Sethi et al.   NEUROSCIENCE

Sleep and Alzheimer's disease

(2015) Laure Peter-Derex et al.   SLEEP MEDICINE REVIEWS

Early neurone loss in Alzheimer’s disease: cortical or subcortical?

(2015) Thomas Arendt et al.   Acta Neuropathologica Communications

Basal Forebrain Cholinergic Modulation of Sleep Transitions

(2014) Simal Ozen Irmak et al.   SLEEP

Glutamatergic Signaling from the Parabrachial Nucleus Plays a Critical Role in Hypercapnic Arousal

(2013) S. Kaur et al.   JOURNAL OF NEUROSCIENCE

Optogenetic Stimulation of MCH Neurons Increases Sleep

(2013) R. R. Konadhode et al.   JOURNAL OF NEUROSCIENCE

Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus

(2013) Sonia Jego et al.   NATURE NEUROSCIENCE

Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

Sleep Quality and Preclinical Alzheimer Disease

(2013) Yo-El S. Ju et al.   JAMA Neurology

Concurrent Impairments in Sleep and Memory in Amnestic Mild Cognitive Impairment

(2012) Carmen E. Westerberg et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

Generalization of the Prion Hypothesis to Other Neurodegenerative Diseases: An Imperfect Fit

(2011) Will C. Guest et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Neuronal activity regulates the regional vulnerability to amyloid-β deposition

(2011) Adam W Bero et al.   NATURE NEUROSCIENCE

Selective Neuronal Vulnerability in Neurodegenerative Diseases: from Stressor Thresholds to Degeneration

(2011) Smita Saxena et al.   NEURON

The pathological process underlying Alzheimer’s disease in individuals under thirty

(2010) Heiko Braak et al.   ACTA NEUROPATHOLOGICA

Neuropathology of variants of progressive supranuclear palsy

(2010) Dennis W Dickson et al.   CURRENT OPINION IN NEUROLOGY

Sleep disorders in neurodegenerative diseases

(2010) A. Raggi et al.   EUROPEAN JOURNAL OF NEUROLOGY

Reassessment of the structural basis of the ascending arousal system

(2010) Patrick Fuller et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Phasic and Tonic Patterns of Locus Coeruleus Output Differentially Modulate Sensory Network Function in the Awake Rat

(2010) David M. Devilbiss et al.   JOURNAL OF NEUROPHYSIOLOGY

Locus coeruleus neuronal activity during the sleep-waking cycle in mice

(2010) K. Takahashi et al.   NEUROSCIENCE

The role of dorsal raphe nucleus serotonergic and non-serotonergic neurons, and of their receptors, in regulating waking and rapid eye movement (REM) sleep

(2010) Jaime M. Monti   SLEEP MEDICINE REVIEWS

The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer's disease. A precocious onset?

(2009) L. T. Grinberg et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Melanin-concentrating hormone neurons discharge in a reciprocal manner to orexin neurons across the sleep-wake cycle

(2009) O. K. Hassani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discrimination ability of individual measures used in sleep stages classification

(2008) Kristína Šušmáková et al.   ARTIFICIAL INTELLIGENCE IN MEDICINE

Neuronal activity of orexin and non-orexin waking-active neurons during wake–sleep states in the mouse

(2008) K. Takahashi et al.   NEUROSCIENCE

Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat

(2008) R.G. Nair-Roberts et al.   NEUROSCIENCE

Noradrenergic modulation of arousal

(2007) Craig W. Berridge   BRAIN RESEARCH REVIEWS