Progressive Loss of the Orexin Neurons Reveals Dual Effects on Wakefulness

Sleep is related to neuron numbers in the ventrolateral preoptic/intermediate nucleus in older adults with and without Alzheimer’s disease

(2014) Andrew S. P. Lim et al.   BRAIN

Conditional Ablation of Orexin/Hypocretin Neurons: A New Mouse Model for the Study of Narcolepsy and Orexin System Function

(2014) S. Tabuchi et al.   JOURNAL OF NEUROSCIENCE

Control of sleep-to-wake transitions via fast amino acid and slow neuropeptide transmission

(2014) Thiago Mosqueiro et al.   NEW JOURNAL OF PHYSICS

Hypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area

(2014) J. W. Muschamp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coreleased Orexin and Glutamate Evoke Nonredundant Spike Outputs and Computations in Histamine Neurons

(2014) Cornelia Schöne et al.   Cell Reports

Increase of histaminergic tuberomammillary neurons in narcolepsy

(2013) Philipp O. Valko et al.   ANNALS OF NEUROLOGY

Greatly increased numbers of histamine cells in human narcolepsy with cataplexy

(2013) Joshi John et al.   ANNALS OF NEUROLOGY

Orexin deficiency and narcolepsy

(2013) Takeshi Sakurai   CURRENT OPINION IN NEUROBIOLOGY

Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus

(2013) Sonia Jego et al.   NATURE NEUROSCIENCE

Narcolepsy: Neural Mechanisms of Sleepiness and Cataplexy

(2012) C. R. Burgess et al.   JOURNAL OF NEUROSCIENCE

Survival analysis indicates that age-related decline in sleep continuity occurs exclusively during NREM sleep

(2012) Elizabeth B. Klerman et al.   NEUROBIOLOGY OF AGING

A Fast-Slow Analysis of the Dynamics of REM Sleep

(2012) Cecilia G. Diniz Behn et al.   SIAM JOURNAL ON APPLIED DYNAMICAL SYSTEMS

Cholinergic Modulation of Narcoleptic Attacks in Double Orexin Receptor Knockout Mice

(2011) Mike Kalogiannis et al.   PLoS One

Simulating Microinjection Experiments in a Novel Model of the Rat Sleep-Wake Regulatory Network

(2010) Cecilia G. Diniz Behn et al.   JOURNAL OF NEUROPHYSIOLOGY

Tuning arousal with optogenetic modulation of locus coeruleus neurons

(2010) Matthew E Carter et al.   NATURE NEUROSCIENCE

Melanin-concentrating hormone neurons discharge in a reciprocal manner to orexin neurons across the sleep-wake cycle

(2009) O. K. Hassani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delayed Orexin Signaling Consolidates Wakefulness and Sleep: Physiology and Modeling

(2008) C. G. Diniz Behn et al.   JOURNAL OF NEUROPHYSIOLOGY