STAT3-YAP/TAZ signaling in endothelial cells promotes tumor angiogenesis

Protein Phosphatase 2A Mediates YAP Activation in Endothelial Cells Upon VEGF Stimulation and Matrix Stiffness

(2021) Xiao Jiang et al.   Frontiers in Cell and Developmental Biology

Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis

(2021) Mahak Singhal et al.   Science Translational Medicine

Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer

(2020) Ying Shen et al.   CANCER CELL

Yes-Associated Protein Promotes Angiogenesis via Signal Transducer and Activator of Transcription 3 in Endothelial CellsNovelty and Significance

(2018) Jinlong He et al.   CIRCULATION RESEARCH

Dynamic Fluctuations in Subcellular Localization of the Hippo Pathway Effector Yorkie In Vivo

(2018) Samuel A. Manning et al.   CURRENT BIOLOGY

YAP/TAZ upstream signals and downstream responses

(2018) Antonio Totaro et al.   NATURE CELL BIOLOGY

YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development

(2018) Filipa Neto et al.   eLife

Cytokines in clinical cancer immunotherapy

(2018) Pedro Berraondo et al.   BRITISH JOURNAL OF CANCER

Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation

(2017) Maretoshi Hirai et al.   JOURNAL OF CLINICAL INVESTIGATION

YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation

(2017) Jongshin Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

YAP/TAZ-CDC42 signaling regulates vascular tip cell migration

(2017) Masahide Sakabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MiR-205/YAP1 in Activated Fibroblasts of Breast Tumor Promotes VEGF-independent Angiogenesis through STAT3 Signaling

(2017) Yan-e Du et al.   Theranostics

YAP/TAZ at the Roots of Cancer

(2016) Francesca Zanconato et al.   CANCER CELL

YAP/TAZ as therapeutic targets in cancer

(2016) Francesca Zanconato et al.   CURRENT OPINION IN PHARMACOLOGY

The Complexity of Translating Anti-angiogenesis Therapy from Basic Science to the Clinic

(2016) Weilan Ye   DEVELOPMENTAL CELL

Importin α1 Mediates Yorkie Nuclear Import via an N-terminal Non-canonical Nuclear Localization Signal

(2016) Shimin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ER Stress and Angiogenesis

(2015) François Binet et al.   Cell Metabolism

YAP Is a Critical Inducer of SOCS3, Preventing Reactive Astrogliosis

(2015) Zhihui Huang et al.   CEREBRAL CORTEX

Vascular Signal Transducer and Activator of Transcription-3 Promotes Angiogenesis and Neuroplasticity Long-Term After Stroke

(2015) C. J. Hoffmann et al.   CIRCULATION

TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data

(2015) Antonio Colaprico et al.   NUCLEIC ACIDS RESEARCH

Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1

(2015) Huabing Zhang et al.   Science Signaling

Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination

(2015) P. Robert Beatty et al.   Science Translational Medicine

Yes-associated protein regulates endothelial cell contact-mediated expression of angiopoietin-2

(2015) Hyun-Jung Choi et al.   Nature Communications

Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1

(2015) Huabing Zhang et al.   Science Signaling

The regulation and function of YAP transcription co-activator

(2014) C. Zhu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Postsurgical Adjuvant Tumor Therapy by Combining Anti-Angiopoietin-2 and Metronomic Chemotherapy Limits Metastatic Growth

(2014) Kshitij Srivastava et al.   CANCER CELL

A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer

(2014) Shi Jiao et al.   CANCER CELL

Dual role of YAP and TAZ in renewal of the intestinal epithelium

(2014) Masamichi Imajo et al.   NATURE CELL BIOLOGY

Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth

(2014) V De Simone et al.   ONCOGENE

The Biology of YAP/TAZ: Hippo Signaling and Beyond

(2014) Stefano Piccolo et al.   PHYSIOLOGICAL REVIEWS

A Novel Inhibitor of STAT3 Homodimerization Selectively Suppresses STAT3 Activity and Malignant Transformation

(2013) X. Zhang et al.   CANCER RESEARCH

Development and characterization of a reliable mouse model of colorectal cancer metastasis to the liver

(2013) Yu Zhang et al.   CLINICAL & EXPERIMENTAL METASTASIS

A genetic screen identifies an LKB1–MARK signalling axis controlling the Hippo–YAP pathway

(2013) Morvarid Mohseni et al.   NATURE CELL BIOLOGY

Hippo pathway effector Yap promotes cardiac regeneration

(2013) Mei Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

A high-throughput approach for measuring temporal changes in the interactome

(2012) Anders R Kristensen et al.   NATURE METHODS

Identifying ChIP-seq enrichment using MACS

(2012) Jianxing Feng et al.   Nature Protocols

The role of the N-terminal domain in dimerization and nucleocytoplasmic shuttling of latent STAT3

(2011) M. Vogt et al.   JOURNAL OF CELL SCIENCE

Opposing roles of angiomotin-like-1 and zona occludens-2 on pro-apoptotic function of YAP

(2011) T Oka et al.   ONCOGENE

Regulation of Insulin-Like Growth Factor Signaling by Yap Governs Cardiomyocyte Proliferation and Embryonic Heart Size

(2011) M. Xin et al.   Science Signaling

Activated STAT3 is a mediator and biomarker of VEGF endothelial activation

(2010) Shao-Hua Chen et al.   CANCER BIOLOGY & THERAPY

Hippo signaling: growth control and beyond

(2010) G. Halder et al.   DEVELOPMENT

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Angiopoietin-2 Levels Are Associated with Disease Progression in Metastatic Malignant Melanoma

(2009) I. Helfrich et al.   CLINICAL CANCER RESEARCH

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

STAT3: A critical transcription activator in angiogenesis

(2007) Zhong Chen et al.   MEDICINAL RESEARCH REVIEWS