Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis

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Angiocrine endothelium: from physiology to cancer

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Preclinical validation of a novel metastasis‐inhibiting Tie1 function‐blocking antibody

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Timed Ang2-targeted therapy identifies the Angiopoietin-Tie pathway as key regulator of fatal lymphogenous metastasis

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Vessel co-option in cancer

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LRG1 Promotes Diabetic Kidney Disease Progression by Enhancing TGF-β–Induced Angiogenesis

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Bone vascular niche E-selectin induces mesenchymal–epithelial transition and Wnt activation in cancer cells to promote bone metastasis

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Comprehensive Integration of Single-Cell Data

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Beyond Angiogenesis: Exploiting Angiocrine Factors to Restrict Tumor Progression and Metastasis

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Collaborative Regulation of LRG1 by TGF-β1 and PPAR-β/δ Modulates Chronic Pressure Overload–Induced Cardiac Fibrosis

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Serum leucine-rich alpha-2-glycoprotein-1 with fucosylated triantennary N-glycan: a novel colorectal cancer marker

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The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium

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Endothelial cell fitness dictates the source of regenerating liver vasculature

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A molecular atlas of cell types and zonation in the brain vasculature

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Hepatic endothelial Notch activation protects against liver metastasis by regulating endothelial-tumor cell adhesion independent of angiocrine signaling

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Early Enhanced Leucine-Rich α-2-Glycoprotein-1 Expression in Glomerular Endothelial Cells of Type 2 Diabetic Nephropathy Model Mice

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KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis

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STAT3 activation in endothelial cells is important for tumor metastasis via increased cell adhesion molecule expression

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Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade

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Combined antiangiogenic and anti–PD-L1 therapy stimulates tumor immunity through HEV formation

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Vessel co-option is common in human lung metastases and mediates resistance to anti-angiogenic therapy in preclinical lung metastasis models

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Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer

(2016) Michela Capello et al.   JNCI-Journal of the National Cancer Institute

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CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma

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Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases

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Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages

(2016) Teresa E. Peterson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival

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Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer

(2016) Michela Capello et al.   JNCI-Journal of the National Cancer Institute

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Emerging translational approaches to target STAT3 signalling and its impact on vascular disease

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Clinicopathological Significance of Leucine-Rich α2-Glycoprotein-1 in Sera of Patients With Pancreatic Cancer

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Accuracy and Reproducibility in Quantification of Plasma Protein Concentrations by Mass Spectrometry without the Use of Isotopic Standards

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Postsurgical Adjuvant Tumor Therapy by Combining Anti-Angiopoietin-2 and Metronomic Chemotherapy Limits Metastatic Growth

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Mechanism of tumour vascularization in experimental lung metastases

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LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling

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Shotgun and targeted proteomics reveal that pre-surgery serum levels of LRG1, SAA, and C4BP may refine prognosis of resected squamous cell lung cancer

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Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection

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Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

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Leucine-rich alpha-2-glycoprotein-1 is upregulated in sera and tumors of ovarian cancer patients

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