Bakuchiol ameliorates cerebral ischemia-reperfusion injury by modulating NLRP3 inflammasome and Nrf2 signaling

NRF2 as a regulator of cell metabolism and inflammation in cancer

(2020) Feng He et al.   CARCINOGENESIS

Bakuchiol Attenuates Oxidative Stress and Neuron Damage by Regulating Trx1/TXNIP and the Phosphorylation of AMPK After Subarachnoid Hemorrhage in Mice

(2020) Haixiao Liu et al.   Frontiers in Pharmacology

Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood–brain barrier

(2020) Judith Hauptmann et al.   ACTA NEUROPATHOLOGICA

Neuroprotective effect of resveratrol against radiation after surgically induced brain injury by reducing oxidative stress, inflammation, and apoptosis through NRf2/HO‐1/NF‐κB signaling pathway

(2020) Yang Zhang et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Bakuchiol Alleviates Hyperglycemia-Induced Diabetic Cardiomyopathy by Reducing Myocardial Oxidative Stress via Activating the SIRT1/Nrf2 Signaling Pathway

(2020) Wenshuai Ma et al.   Oxidative Medicine and Cellular Longevity

Bakuchiol: A newly discovered warrior against organ damage

(2019) Zhenlong Xin et al.   PHARMACOLOGICAL RESEARCH

Dual Functions of Microglia in Ischemic Stroke

(2019) Chuan Qin et al.   Neuroscience Bulletin

Bakuchiol Suppresses Inflammatory Responses Via the Downregulation of the p38 MAPK/ERK Signaling Pathway

(2019) Hye-Sun Lim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Extracellular ASC exacerbated the recurrent ischemic stroke in an NLRP3-dependent manner

(2019) Xiao-fei He et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Heme oxygenase-1/carbon monoxide as modulators of autophagy and inflammation

(2019) Stefan W. Ryter   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A Dual AMPK/Nrf2 Activator Reduces Brain Inflammation After Stroke by Enhancing Microglia M2 Polarization

(2018) Yunjie Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Nrf2 inhibits NLRP3 inflammasome activation through regulating Trx1/TXNIP complex in cerebral ischemia reperfusion injury

(2018) Yanghao Hou et al.   BEHAVIOURAL BRAIN RESEARCH

Inhibition of the NLRP3-inflammasome as a potential approach for neuroprotection after stroke

(2018) Saifudeen Ismael et al.   Scientific Reports

Uric Acid Protects against Focal Cerebral Ischemia/Reperfusion-Induced Oxidative Stress via Activating Nrf2 and Regulating Neurotrophic Factor Expression

(2018) Bai-liu Ya et al.   Oxidative Medicine and Cellular Longevity

Nrf2/ARE pathway inhibits ROS-induced NLRP3 inflammasome activation in BV2 cells after cerebral ischemia reperfusion

(2017) Xiujian Xu et al.   INFLAMMATION RESEARCH

Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway

(2017) Jun Zeng et al.   Journal of Neuroinflammation

The biphasic function of microglia in ischemic stroke

(2017) Yuanyuan Ma et al.   PROGRESS IN NEUROBIOLOGY

Transcriptional Regulation by Nrf2

(2017) Claudia Tonelli et al.   ANTIOXIDANTS & REDOX SIGNALING

Bakuchiol attenuates myocardial ischemia reperfusion injury by maintaining mitochondrial function: the role of silent information regulator 1

(2016) Jianyu Feng et al.   APOPTOSIS

NLRP3 inflammasome: a promising target in ischemic stroke

(2016) Li Gao et al.   INFLAMMATION RESEARCH

Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation

(2016) Ángel Chamorro et al.   LANCET NEUROLOGY

Quantitative Analysis of Psoralea corylifolia Linne and its Neuroprotective and Anti-Neuroinflammatory Effects in HT22 Hippocampal Cells and BV-2 Microglia

(2016) Yu Kim et al.   MOLECULES

Role of Inflammasome Activation in the Pathophysiology of Vascular Diseases of the Neurovascular Unit

(2015) Islam N. Mohamed et al.   ANTIOXIDANTS & REDOX SIGNALING

Applications of the Keap1–Nrf2 system for gene and cell therapy

(2015) Katja M. Kanninen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Bakuchiol Is a Phenolic Isoprenoid with Novel Enantiomer-selective Anti-influenza A Virus Activity Involving Nrf2 Activation

(2015) Masaki Shoji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Future directions of acute ischaemic stroke therapy

(2015) Marc Fisher et al.   LANCET NEUROLOGY

AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3

(2015) Adam Denes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rational modulation of the innate immune system for neuroprotection in ischemic stroke

(2015) Diana Amantea et al.   Frontiers in Neuroscience

Extracellular histones in tissue injury and inflammation

(2014) Ramanjaneyulu Allam et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Pathogenesis of acute stroke and the role of inflammasomes

(2013) David Yang-Wei Fann et al.   AGEING RESEARCH REVIEWS

Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke

(2013) D Yang-Wei Fann et al.   Cell Death & Disease

Optimal Percoll concentration facilitates flow cytometric analysis for annexin V/propidium iodine-stained ischemic brain tissues

(2012) Wei-Sheng Juan et al.   CYTOMETRY PART A

Estrogenic activities of Psoralea corylifolia L. seed extracts and main constituents

(2011) Sun-Hye Lim et al.   PHYTOMEDICINE

Mouse Model of Middle Cerebral Artery Occlusion

(2011) Terrance Chiang et al.   Jove-Journal of Visualized Experiments

Inhibitory Effects of Bakuchiol, Bavachin, and Isobavachalcone Isolated fromPiper longumon Melanin Production in B16 Mouse Melanoma Cells

(2010) Osamu OHNO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Anti-tumor effects of bakuchiol, an analogue of resveratrol, on human lung adenocarcinoma A549 cell line

(2010) Zhe Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Isolation and Anti-Inflammatory Activity of Bakuchiol from Ulmus davidiana var. japonica

(2010) Sang Yoon Choi et al.   JOURNAL OF MEDICINAL FOOD

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY