Loss of association between plasma irisin levels and cognition in Alzheimer’s disease

How does the skeletal muscle communicate with the brain in health and disease?

(2021) Alinny R. Isaac et al.   NEUROPHARMACOLOGY

Protective actions of exercise‐related FNDC5/Irisin in memory and Alzheimer's disease

(2020) Guilherme B. de Freitas et al.   JOURNAL OF NEUROCHEMISTRY

Circulating levels of Irisin in obese individuals at genetic risk for Alzheimer’s disease: Correlations with amyloid-β, metabolic, and neurocognitive indices

(2020) Chia-Liang Tsai et al.   BEHAVIOURAL BRAIN RESEARCH

A role for FNDC5/Irisin in the beneficial effects of exercise on the brain and in neurodegenerative diseases

(2019) Michael F. Young et al.   PROGRESS IN CARDIOVASCULAR DISEASES

The effects of both age and sex on irisin levels in paired plasma and cerebrospinal fluid in healthy humans

(2019) Qingwei Ruan et al.   PEPTIDES

Irisin and BDNF serum levels and behavioral disturbances in Alzheimer’s disease

(2019) Elisa Conti et al.   NEUROLOGICAL SCIENCES

Irisin Attenuates Neuroinflammation and Prevents the Memory and Cognitive Deterioration in Streptozotocin-Induced Diabetic Mice

(2019) Kexin Wang et al.   MEDIATORS OF INFLAMMATION

In Addition to Poor Glycemic Control, a High Level of Irisin in the Plasma Portends Early Cognitive Deficits Clinically in Chinese Patients With Type 2 Diabetes Mellitus

(2019) Hongyan Lin et al.   Frontiers in Endocrinology

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

(2018) Steven E. Arnold et al.   Nature Reviews Neurology

Central irisin administration affords antidepressant-like effect and modulates neuroplasticity-related genes in the hippocampus and prefrontal cortex of mice

(2018) Aline Siteneski et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

(2018) Mychael V. Lourenco et al.   NATURE MEDICINE

Influence of hypertension on brain amyloid deposition and Alzheimer's disease signature neurodegeneration

(2018) So Yeon Jeon et al.   NEUROBIOLOGY OF AGING

Novel Blood-Based Biomarkers of Cognition, Stress, and Physical or Cognitive Training in Older Adults at Risk of Dementia: Preliminary Evidence for a Role of BDNF, Irisin, and the Kynurenine Pathway

(2017) Olivia C. Küster et al.   JOURNAL OF ALZHEIMERS DISEASE

Physiology and role of irisin in glucose homeostasis

(2017) Nikolaos Perakakis et al.   Nature Reviews Endocrinology

The relationship between brain-derived neurotrophic factor, irisin and cognitive skills of endurance athletes

(2016) Muaz Belviranli et al.   PHYSICIAN AND SPORTSMEDICINE

Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry

(2015) Mark P. Jedrychowski et al.   Cell Metabolism

Serum Irisin Levels Are Regulated by Acute Strenuous Exercise

(2015) Dennis Löffler et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Exercise-Induced Irisin Secretion Is Independent of Age or Fitness Level and Increased Irisin May Directly Modulate Muscle Metabolism Through AMPK Activation

(2014) Joo Young Huh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Exercise, Energy Intake, Glucose Homeostasis, and the Brain

(2014) H. van Praag et al.   JOURNAL OF NEUROSCIENCE

Physical activity attenuates age-related biomarker alterations in preclinical AD

(2014) O. C. Okonkwo et al.   NEUROLOGY

Automated Segmentation and Quantification of White Matter Hyperintensities in Acute Ischemic Stroke Patients with Cerebral Infarction

(2014) Jang-Zern Tsai et al.   PLoS One

The beneficial effects of strength exercise on hippocampal cell proliferation and apoptotic signaling is impaired by anabolic androgenic steroids

(2014) Fabiano Guimarães Novaes Gomes et al.   PSYCHONEUROENDOCRINOLOGY

Impact of acute aerobic exercise and cardiorespiratory fitness on visuospatial attention performance and serum BDNF levels

(2014) Chia-Liang Tsai et al.   PSYCHONEUROENDOCRINOLOGY

Physical exercise neuroprotects ovariectomized 3xTg-AD mice through BDNF mechanisms

(2014) Yoelvis García-Mesa et al.   PSYCHONEUROENDOCRINOLOGY

Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway

(2013) Christiane D. Wrann et al.   Cell Metabolism

Circulating Irisin in Relation to Insulin Resistance and the Metabolic Syndrome

(2013) Kyung Hee Park et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Effect of Intranasal Insulin on Cognitive Function: A Systematic Review

(2011) Elad Shemesh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Intense exercise increases circulating endocannabinoid and BDNF levels in humans—Possible implications for reward and depression

(2011) E. Heyman et al.   PSYCHONEUROENDOCRINOLOGY

Effects of Aerobic Exercise on Mild Cognitive Impairment

(2010) Laura D. Baker et al.   ARCHIVES OF NEUROLOGY

Diagnosis and Classification of Diabetes Mellitus

(2009)   DIABETES CARE