Identification of potentially anti-COVID-19 active drugs using the connectivity MAP

Viral strategies for circumventing p53

(2021) Camila Martin Cardozo et al.   CURRENT OPINION IN ONCOLOGY

Drug Repurposing to Treat Glucocorticoid Resistance in Asthma

(2021) Alberta L. Wang et al.   Journal of Personalized Medicine

Integrated bioinformatic analysis reveals the underlying molecular mechanism of and potential drugs for pulmonary arterial hypertension

(2021) Haoru Dong et al.   Aging-US

SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2

(2021) Yuyang Lei et al.   CIRCULATION RESEARCH

The potential role of nucleophosmin (NPM1) in the development of cancer

(2021) Fateme Karimi Dermani et al.   JOURNAL OF CELLULAR PHYSIOLOGY

SARS-CoV-2 vaccines: a triumph of science and collaboration

(2021) Jonathan L. Golob et al.   JCI Insight

Identifying FDA-approved drugs with multimodal properties against COVID-19 using a data-driven approach and a lung organoid model of SARS-CoV-2 entry

(2021) Rodrigo R. R. Duarte et al.   MOLECULAR MEDICINE

Implications of SARS-Cov-2 infection on eNOS and iNOS activity: Consequences for the respiratory and vascular systems

(2021) Lara M.F. Guimarães et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Drugs repurposed for COVID-19 by virtual screening of 6,218 drugs and cell-based assay

(2021) Woo Dae Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication

(2021) Caroline G. Williams et al.   Cell Reports

Connectivity Map Analysis Indicates PI3K/Akt/mTOR Inhibitors as Potential Anti-Hypoxia Drugs in Neuroblastoma

(2021) Paolo Uva et al.   Cancers

Metformin to decrease COVID-19 severity and mortality: Molecular mechanisms and therapeutic potential

(2021) Olexandr Kamyshnyi et al.   BIOMEDICINE & PHARMACOTHERAPY

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

Drug repurposing against COVID-19: focus on anticancer agents

(2020) Gennaro Ciliberto et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The hallmarks of COVID-19 disease

(2020) Daolin Tang et al.   PLoS Pathogens

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

Plausibility of therapeutic effects of Rho kinase inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (COVID-19)

(2020) Farshad Abedi et al.   PHARMACOLOGICAL RESEARCH

Glycogen synthase kinase-3: A putative target to combat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic

(2020) Anil Kumar Rana et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19

(2020) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A Novel Pipeline for Drug Repurposing for Bladder Cancer Based on Patients’ Omics Signatures

(2020) Marika Mokou et al.   Cancers

An Integrated Bioinformatics Analysis Repurposes an Antihelminthic Drug Niclosamide for Treating HMGA2-Overexpressing Human Colorectal Cancer

(2019) Leung et al.   Cancers

Treatment with the NR4A1 agonist cytosporone B controls influenza virus infection and improves pulmonary function in infected mice

(2017) Benoit Egarnes et al.   PLoS One

NR4A1-dependent Ly6Clowmonocytes contribute to reducing joint inflammation in arthritic mice through Treg cells

(2016) Alexandre Brunet et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Computational Repositioning and Preclinical Validation of Pentamidine for Renal Cell Cancer

(2014) L. F. Zerbini et al.   MOLECULAR CANCER THERAPEUTICS

Applications of Connectivity Map in drug discovery and development

(2012) Xiaoyan A. Qu et al.   DRUG DISCOVERY TODAY

Gene Expression Signature-Based Screening Identifies New Broadly Effective Influenza A Antivirals

(2010) Laurence Josset et al.   PLoS One