Treatment with the NR4A1 agonist cytosporone B controls influenza virus infection and improves pulmonary function in infected mice

NR4A Receptors Differentially Regulate NF-κB Signaling in Myeloid Cells

(2017) Caitriona McEvoy et al.   Frontiers in Immunology

NR4A1-dependent Ly6Clowmonocytes contribute to reducing joint inflammation in arthritic mice through Treg cells

(2016) Alexandre Brunet et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Monocytes and macrophages in tissue repair: Implications for immunoregenerative biomaterial design

(2016) Molly E Ogle et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Health Care–Acquired Viral Respiratory Diseases

(2016) Ryan K. Dare et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Deletion of Irf3 and Irf7 Genes in Mice Results in Altered Interferon Pathway Activation and Granulocyte-Dominated Inflammatory Responses to Influenza A Infection

(2016) Bastian Hatesuer et al.   Journal of Innate Immunity

NUR77 exerts a protective effect against inflammatory bowel disease by negatively regulating the TRAF6/TLR-IL-1R signalling axis

(2015) Hua Wu et al.   JOURNAL OF PATHOLOGY

Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation

(2015) Li Li et al.   Nature Chemical Biology

Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency

(2015) M. J. Ciancanelli et al.   SCIENCE

Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages

(2015) Anouk A. J. Hamers et al.   PLoS One

Ly-6C high Monocytes Depend on Nr4a1 to Balance Both Inflammatory and Reparative Phases in the Infarcted Myocardium

(2014) Ingo Hilgendorf et al.   CIRCULATION RESEARCH

Leukotriene B 4 Induces Release of Antimicrobial Peptides in Lungs of Virally Infected Mice

(2014) Éric Gaudreault et al.   JOURNAL OF IMMUNOLOGY

Activation of the Interferon Induction Cascade by Influenza A Viruses Requires Viral RNA Synthesis and Nuclear Export

(2014) M. J. Killip et al.   JOURNAL OF VIROLOGY

Nur77 Decreases Atherosclerosis Progression in apoE−/− Mice Fed a High-Fat/High-Cholesterol Diet

(2014) Yan-Wei Hu et al.   PLoS One

Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection

(2014) Christoph Schneider et al.   PLoS Pathogens

From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation

(2014) Paola Italiani et al.   Frontiers in Immunology

Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal

(2013) Leo M. Carlin et al.   CELL

Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis

(2013) Takashi Sekiya et al.   NATURE IMMUNOLOGY

TAK1 contributes to the enhanced responsiveness of LTB4-treated neutrophils to Toll-like receptor ligands

(2012) E. Gaudreault et al.   INTERNATIONAL IMMUNOLOGY

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

(2012) Hongwei Yao et al.   JOURNAL OF CLINICAL INVESTIGATION

Innate Immune Response of Human Alveolar Macrophages during Influenza A Infection

(2012) Jieru Wang et al.   PLoS One

Muramyl Dipeptide Induces NOD2-Dependent Ly6Chigh Monocyte Recruitment to the Lungs and Protects Against Influenza Virus Infection

(2012) François Coulombe et al.   PLoS One

Inflammation: a role for NR4A orphan nuclear receptors?

(2011) Jason P. McMorrow et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

NR4A1 (Nur77) Deletion Polarizes Macrophages Toward an Inflammatory Phenotype and Increases Atherosclerosis

(2011) Richard N. Hanna et al.   CIRCULATION RESEARCH

The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C− monocytes

(2011) Richard N Hanna et al.   NATURE IMMUNOLOGY

NR4A Orphan Nuclear Receptors

(2010) Yue Zhao et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Deficiency of the NR4A Orphan Nuclear Receptor NOR1 Decreases Monocyte Adhesion and Atherosclerosis

(2010) Yue Zhao et al.   CIRCULATION RESEARCH

Vaccination strategies and vaccine formulations for epidemic and pandemic influenza control

(2010) Joost H.C.M. Kreijtz et al.   Human vaccines & immunotherapeutics

Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM

(2010) H. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative Pathology of Select Agent Influenza A Virus Infections

(2010) T. Kuiken et al.   VETERINARY PATHOLOGY

Dating the emergence of pandemic influenza viruses

(2009) Gavin J. D. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pathology of Influenza Virus Infections

(2008) Jeffery K. Taubenberger et al.   Annual Review of Pathology-Mechanisms of Disease

Cytosporone B is an agonist for nuclear orphan receptor Nur77

(2008) Yanyan Zhan et al.   Nature Chemical Biology

Influenza vaccine strain selection and recent studies on the global migration of seasonal influenza viruses

(2008) Colin A. Russell et al.   VACCINE