Long noncoding RNA p21 enhances autophagy to alleviate endothelial progenitor cells damage and promote endothelial repair in hypertension through SESN2/AMPK/TSC2 pathway

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Rhynchophylline Attenuates Senescence of Endothelial Progenitor Cells by Enhancing Autophagy

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Sestrin2 as a potential therapeutic target for cardiovascular diseases

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Angiotensin II and vascular damage in hypertension: Role of oxidative stress and sympathetic activation

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Nrf2-lncRNA controls cell fate by modulating p53-dependent Nrf2 activation as an miRNA sponge for Plk2 and p21cip1

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(2019) Mark S D’Arcy   CELL BIOLOGY INTERNATIONAL

Berberine reduces endothelial injury and arterial stiffness in spontaneously hypertensive rats

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(2019) Zhanbing Ma et al.   PLoS One

lncRNA GAS5 Inhibits Cell Migration and Invasion and Promotes Autophagy by Targeting miR-222-3p via the GAS5/PTEN-Signaling Pathway in CRC

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MiR‐205 promotes endothelial progenitor cell angiogenesis and deep vein thrombosis recanalization and resolution by targeting PTEN to regulate Akt/autophagy pathway and MMP2 expression

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Autophagy plays a critical role in Klotho gene deficiency-induced arterial stiffening and hypertension

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Overexpression of long non-coding RNA H19 promotes invasion and autophagy via the PI3K/AKT/mTOR pathways in trophoblast cells

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Defective Autophagy in Atherosclerosis: To Die or to Senesce?

(2018) Mandy O. J. Grootaert et al.   Oxidative Medicine and Cellular Longevity

Effect of intensive multifactorial treatment on vascular progenitor cells in hypertensive patients

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LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription

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Endothelial Progenitor Cells as Molecular Targets in Vascular Senescence and Repair

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Knockdown of lncRNA AK139328 alleviates myocardial ischaemia/reperfusion injury in diabetic mice via modulating miR-204-3p and inhibiting autophagy

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The endothelial status reflected by circulating endothelial cells, circulating endothelial progenitor cells and soluble thrombomodulin in patients with mild and resistant hypertension

(2018) Magdalena Budzyń et al.   VASCULAR PHARMACOLOGY

Angiotensin II Attenuates the Bioactivities of Human Endothelial Progenitor Cells via Downregulation of β2-Adrenergic Receptor

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Sitagliptin-mediated preservation of endothelial progenitor cell function via augmenting autophagy enhances ischaemic angiogenesis in diabetes

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Monotropein promotes angiogenesis and inhibits oxidative stress-induced autophagy in endothelial progenitor cells to accelerate wound healing

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Long intergenic noncoding RNA p21 mediates oxidized LDL-induced apoptosis and expression of LOX-1 in human coronary artery endothelial cells

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The Use of Endothelial Progenitor Cells for the Regeneration of Musculoskeletal and Neural Tissues

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Endothelial progenitor cells participation in cardiovascular and kidney diseases: a systematic review

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Quercitrin treatment protects endothelial progenitor cells from oxidative damage via inducing autophagy through extracellular signal-regulated kinase

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Endothelial progenitor cells and hypertension: current concepts and future implications

(2016) S. Luo et al.   CLINICAL SCIENCE

The Role of Long Intergenic Noncoding RNA p21 in Vascular Endothelial Cells

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Icariin Promotes Angiogenic Differentiation and Prevents Oxidative Stress-Induced Autophagy in Endothelial Progenitor Cells

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LincRNA-p21 acts as a mediator of ING1b-induced apoptosis

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Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes

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Are Endothelial Progenitor Cells the Real Solution for Cardiovascular Diseases? Focus on Controversies and Perspectives

(2015) Carmela R. Balistreri et al.   Biomed Research International

Histone Deacetylase Inhibition Blunts Ischemia/Reperfusion Injury by Inducing Cardiomyocyte Autophagy

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LincRNA-p21 Regulates Neointima Formation, Vascular Smooth Muscle Cell Proliferation, Apoptosis, and Atherosclerosis by Enhancing p53 Activity

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Quantitative and functional characteristics of endothelial progenitor cells in newly diagnosed hypertensive patients

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LincRNA-p21 Activates p21 In cis to Promote Polycomb Target Gene Expression and to Enforce the G1/S Checkpoint

(2014) Nadya Dimitrova et al.   MOLECULAR CELL

Co-Transplantation of Endothelial Progenitor Cells and Pancreatic Islets to Induce Long-Lasting Normoglycemia in Streptozotocin-Treated Diabetic Rats

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An Overview of Autophagy: Morphology, Mechanism, and Regulation

(2013) Katherine R. Parzych et al.   ANTIOXIDANTS & REDOX SIGNALING

Nox2-Induced Production of Mitochondrial Superoxide in Angiotensin II-Mediated Endothelial Oxidative Stress and Hypertension

(2013) Sergey I. Dikalov et al.   ANTIOXIDANTS & REDOX SIGNALING

Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses

(2013) D. Kenzelmann Broz et al.   GENES & DEVELOPMENT

Redox-Sensitive Endoplasmic Reticulum Stress and Autophagy at Rostral Ventrolateral Medulla Contribute to Hypertension in Spontaneously Hypertensive Rats

(2013) Yung-Mei Chao et al.   HYPERTENSION

Reciprocal Regulation of HIF-1α and LincRNA-p21 Modulates the Warburg Effect

(2013) Fan Yang et al.   MOLECULAR CELL

Essential Hypertension: An Approach to Its Etiology and Neurogenic Pathophysiology

(2013) Juan J. Bolívar   International Journal of Hypertension

Cellular biomarkers of endothelial health: microparticles, endothelial progenitor cells, and circulating endothelial cells

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Autophagy: Renovation of Cells and Tissues

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Persistent Macrovascular and Microvascular Dysfunction in Patients With Malignant Hypertension

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Noncoding RNAs: The Missing “Linc” in p53-Mediated Repression

(2010) Anthony M. Barsotti et al.   CELL

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

Therapeutic Targeting of Mitochondrial Superoxide in Hypertension

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Vascular Endothelial Function and Hypertension: Insights and Directions

(2010) Kodlipet Dharmashankar et al.   CURRENT HYPERTENSION REPORTS

P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

(2010) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beneficial Effects of Mammalian Target of Rapamycin Inhibition on Left Ventricular Remodeling After Myocardial Infarction

(2009) Sebastian J. Buss et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling

(2008) Andrei V. Budanov et al.   CELL

p53 Strikes mTORC1 by Employing Sestrins

(2008) Nissim Hay   Cell Metabolism