Monotropein promotes angiogenesis and inhibits oxidative stress-induced autophagy in endothelial progenitor cells to accelerate wound healing

Quercitrin treatment protects endothelial progenitor cells from oxidative damage via inducing autophagy through extracellular signal-regulated kinase

(2016) Kangkang Zhi et al.   ANGIOGENESIS

Monotropein isolated from the roots of Morinda officinalis increases osteoblastic bone formation and prevents bone loss in ovariectomized mice

(2016) Zhiguo Zhang et al.   FITOTERAPIA

Mechanisms underlying the antiapoptotic and anti-inflammatory effects of monotropein in hydrogen peroxide-treated osteoblasts

(2016) Fang-Bing Zhu et al.   Molecular Medicine Reports

Exacerbated and prolonged inflammation impairs wound healing and increases scarring

(2016) Li-Wu Qian et al.   WOUND REPAIR AND REGENERATION

Bioglass Activated Skin Tissue Engineering Constructs for Wound Healing

(2015) Hongfei Yu et al.   ACS Applied Materials & Interfaces

Wound dressings composed of copper-doped borate bioactive glass microfibers stimulate angiogenesis and heal full-thickness skin defects in a rodent model

(2015) Shichang Zhao et al.   BIOMATERIALS

Heme oxygenase-2 deletion impairs macrophage function: implication in wound healing

(2015) Lars Bellner et al.   FASEB JOURNAL

Targeting vascular and leukocyte communication in angiogenesis, inflammation and fibrosis

(2015) Johan Kreuger et al.   NATURE REVIEWS DRUG DISCOVERY

Icariin Promotes Angiogenic Differentiation and Prevents Oxidative Stress-Induced Autophagy in Endothelial Progenitor Cells

(2015) Yubo Tang et al.   STEM CELLS

Salidroside improves endothelial function and alleviates atherosclerosis by activating a mitochondria-related AMPK/PI3K/Akt/eNOS pathway

(2015) Sha-Sha Xing et al.   VASCULAR PHARMACOLOGY

A critical role of superoxide anion in selenite-induced mitophagic cell death

(2014) Eun Hee Kim et al.   Autophagy

Is mitochondrial generation of reactive oxygen species a trigger for autophagy?

(2014) Yongqiang Chen et al.   Autophagy

High Glucose Condition Induces Autophagy in Endothelial Progenitor Cells Contributing to Angiogenic Impairment

(2014) Kyeong-A Kim et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Chronic Venous Insufficiency

(2014) Robert T. Eberhardt et al.   CIRCULATION

Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics

(2014) Anna-Liisa Levonen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes

(2014) Feng Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Genetically induced oxidative stress in mice causes thrombocytosis, splenomegaly and placental angiodysplasia that leads to recurrent abortion

(2014) Takamasa Ishii et al.   Redox Biology

Vascular Complications of Diabetes: Mechanisms of Injury and Protective Factors

(2013) Christian Rask-Madsen et al.   Cell Metabolism

α-santalol inhibits the angiogenesis and growth of human prostate tumor growth by targeting vascular endothelial growth factor receptor 2-mediated AKT/mTOR/P70S6K signaling pathway

(2013) Sarita Saraswati et al.   Molecular Cancer

Autophagic cell death exists

(2012) Peter G.H. Clarke et al.   Autophagy

Autophagy

(2012) Ricky H. Bhogal et al.   Autophagy

The end of autophagic cell death?

(2012) Shensi Shen et al.   Autophagy

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Monotropein isolated from the roots of Morinda officinalis ameliorates proinflammatory mediators in RAW 264.7 macrophages and dextran sulfate sodium (DSS)-induced colitis via NF-κB inactivation

(2012) Ji-Sun Shin et al.   FOOD AND CHEMICAL TOXICOLOGY

Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation

(2011) Chuan-Ming Xie et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protective role of Gipie, a Girdin family protein, in endoplasmic reticulum stress responses in endothelial cells

(2011) Etsushi Matsushita et al.   MOLECULAR BIOLOGY OF THE CELL

Trauma-Activated Polymorphonucleated Leukocytes Damage Endothelial Progenitor Cells

(2011) Dirk Henrich et al.   SHOCK

Targeting the pro-death and pro-survival functions of autophagy as novel therapeutic strategies in cancer

(2010) Kevin Dalby et al.   Autophagy

Enhanced angiogenesis of gene-activated dermal equivalent for treatment of full thickness incisional wounds in a porcine model

(2010) Rui Guo et al.   BIOMATERIALS

Endothelial progenitor cell transplantation improves long-term stroke outcome in mice

(2009) Yongfeng Fan et al.   ANNALS OF NEUROLOGY

Alzheimer Disease–Associated Peptide, Amyloid β40, Inhibits Vascular Regeneration With Induction of Endothelial Autophagy

(2009) Shin-ichiro Hayashi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

To die or to live: the dual role of poly(ADP-ribose) polymerase-1 in autophagy and necrosis under oxidative stress and DNA damage

(2009) Qing Huang et al.   Autophagy

Role of oxidative stress in vinorelbine-induced vascular endothelial cell injury

(2009) Takaaki Yamada et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Non-canonical MEK/ERK Signaling Pathway Regulates Autophagy via Regulating Beclin 1

(2009) Jianrong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endothelial Progenitor Cells, Endothelial Dysfunction, Inflammation, and Oxidative Stress in Hypertension

(2008) Timothy Watson et al.   ANTIOXIDANTS & REDOX SIGNALING

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE