Impact of Surfactants on the Performance of Clopidogrel-Copovidone Amorphous Solid Dispersions: Increased Drug Loading and Stabilization of Nanodroplets

Drug Release and Nanodroplet Formation from Amorphous Solid Dispersions: Insight into the Roles of Drug Physicochemical Properties and Polymer Selection

(2021) Ruochen Yang et al.   MOLECULAR PHARMACEUTICS

Exploring the Role of Surfactants in Enhancing Drug Release from Amorphous Solid Dispersions at Higher Drug Loadings

(2021) Sugandha Saboo et al.   Pharmaceutics

Polymer Type Impacts Amorphous Solubility and Drug-Rich Phase Colloidal Stability: A Mechanistic Study Using Nuclear Magnetic Resonance Spectroscopy

(2020) Keisuke Ueda et al.   MOLECULAR PHARMACEUTICS

Congruent release of drug and polymer from amorphous solid dispersions: insights into the role of drug-polymer hydrogen bonding, surface crystallization and glass transition

(2020) Sugandha Saboo et al.   MOLECULAR PHARMACEUTICS

Patterns of drug release as a function of drug loading from amorphous solid dispersions: A comparison of five different polymers.

(2020) Sugandha Saboo et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Partitioning of surfactant into drug-rich nanodroplets and its impact on drug thermodynamic activity and droplet size

(2020) Keisuke Ueda et al.   JOURNAL OF CONTROLLED RELEASE

Assessing Physical Stability of Colloidal Dispersions Using Turbiscan Optical Analyzer

(2019) Yan Sun et al.   MOLECULAR PHARMACEUTICS

Insights into the Dissolution Mechanism of Ritonavir–Copovidone Amorphous Solid Dispersions: Importance of Congruent Release for Enhanced Performance

(2019) Anura S. Indulkar et al.   MOLECULAR PHARMACEUTICS

Congruent release of drug and polymer: A “sweet spot” in the dissolution of amorphous solid dispersions

(2019) Sugandha Saboo et al.   JOURNAL OF CONTROLLED RELEASE

Effect of Amorphous Nanoparticle Size on Bioavailability of Anacetrapib in Dogs

(2019) Filippos Kesisoglou et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Molecular Mobility Suppression of Ibuprofen-Rich Amorphous Nanodroplets by HPMC Revealed by NMR Relaxometry and Its Significance with Respect to Crystallization Inhibition

(2019) Keisuke Ueda et al.   MOLECULAR PHARMACEUTICS

Insights into the Dissolution Behavior of Ledipasvir–Copovidone Amorphous Solid Dispersions: Role of Drug Loading and Intermolecular Interactions

(2019) Chailu Que et al.   MOLECULAR PHARMACEUTICS

Impact of Monomeric versus Micellar Surfactant and Surfactant–Polymer Interactions on Nucleation–Induction Times of Atazanavir from Supersaturated Solutions

(2019) Anura S. Indulkar et al.   CRYSTAL GROWTH & DESIGN

Impact of amorphization and GI physiology on supersaturation and precipitation of poorly soluble weakly basic drugs using a small-scale in vitro transfer model

(2019) Carolin Auch et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Amorphous solid dispersions and nanocrystal technologies for poorly water-soluble drug delivery – An update

(2018) Scott V. Jermain et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Influence of Polymer and Drug Loading on the Release Profile and Membrane Transport of Telaprevir

(2018) Laura I. Mosquera-Giraldo et al.   MOLECULAR PHARMACEUTICS

Colloidal aggregation: From screening nuisance to formulation nuance

(2018) Ahil N. Ganesh et al.   Nano Today

Relationship between amorphous solid dispersion in vivo absorption and in vitro dissolution: phase behavior during dissolution, speciation, and membrane mass transport

(2018) Venecia Wilson et al.   JOURNAL OF CONTROLLED RELEASE

Effects of Surfactants on Itraconazole-HPMCAS Solid Dispersion Prepared by Hot-Melt Extrusion I: Miscibility and Drug Release

(2018) Nayan G. Solanki et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Origin of Nanodroplet Formation Upon Dissolution of an Amorphous Solid Dispersion: A Mechanistic Isotope Scrambling Study

(2017) Anura S. Indulkar et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Impact of Drug-Rich Colloids of Itraconazole and HPMCAS on Membrane Flux in Vitro and Oral Bioavailability in Rats

(2017) Aaron M. Stewart et al.   MOLECULAR PHARMACEUTICS

Direct NMR Monitoring of Phase Separation Behavior of Highly Supersaturated Nifedipine Solution Stabilized with Hypromellose Derivatives

(2017) Keisuke Ueda et al.   MOLECULAR PHARMACEUTICS

Impact of Micellar Surfactant on Supersaturation and Insight into Solubilization Mechanisms in Supersaturated Solutions of Atazanavir

(2017) Anura S. Indulkar et al.   PHARMACEUTICAL RESEARCH

Phase Behavior of Ritonavir Amorphous Solid Dispersions during Hydration and Dissolution

(2017) Hitesh S. Purohit et al.   PHARMACEUTICAL RESEARCH

Insights into Nano- and Micron-Scale Phase Separation in Amorphous Solid Dispersions Using Fluorescence-Based Techniques in Combination with Solid State Nuclear Magnetic Resonance Spectroscopy

(2017) Hitesh S. Purohit et al.   PHARMACEUTICAL RESEARCH

Physical chemistry of supersaturated solutions and implications for oral absorption

(2016) Lynne S. Taylor et al.   ADVANCED DRUG DELIVERY REVIEWS

DLS and zeta potential – What they are and what they are not?

(2016) Sourav Bhattacharjee   JOURNAL OF CONTROLLED RELEASE

Mechanism of Dissolution-Induced Nanoparticle Formation from a Copovidone-Based Amorphous Solid Dispersion

(2016) Paul Harmon et al.   MOLECULAR PHARMACEUTICS

Exploiting the Phenomenon of Liquid–Liquid Phase Separation for Enhanced and Sustained Membrane Transport of a Poorly Water-Soluble Drug

(2016) Anura S. Indulkar et al.   MOLECULAR PHARMACEUTICS

Predicting the Solubility Advantage of Amorphous Pharmaceuticals: A Novel Thermodynamic Approach

(2015) Raphael Paus et al.   MOLECULAR PHARMACEUTICS

Glass–Liquid Phase Separation in Highly Supersaturated Aqueous Solutions of Telaprevir

(2015) Laura I. Mosquera-Giraldo et al.   MOLECULAR PHARMACEUTICS

pH-Dependent Liquid–Liquid Phase Separation of Highly Supersaturated Solutions of Weakly Basic Drugs

(2015) Anura S. Indulkar et al.   MOLECULAR PHARMACEUTICS

Impact of Surfactants on the Crystallization of Aqueous Suspensions of Celecoxib Amorphous Solid Dispersion Spray Dried Particles

(2015) Jie Chen et al.   MOLECULAR PHARMACEUTICS

Drug–Polymer–Water Interaction and Its Implication for the Dissolution Performance of Amorphous Solid Dispersions

(2015) Yuejie Chen et al.   MOLECULAR PHARMACEUTICS

Impact of Solubilizing Additives on Supersaturation and Membrane Transport of Drugs

(2015) Shweta A. Raina et al.   PHARMACEUTICAL RESEARCH

Molecular Dynamics Simulations of Structure–Property Relationships of Tween 80 Surfactants in Water and at Interfaces

(2014) Xueming Tang et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Broadband WET: a novel technique for quantitative characterization of minor components in foods

(2014) Kazuo Furihata et al.   MAGNETIC RESONANCE IN CHEMISTRY

Liquid–Liquid Phase Separation in Highly Supersaturated Aqueous Solutions of Poorly Water-Soluble Drugs: Implications for Solubility Enhancing Formulations

(2013) Grace A. Ilevbare et al.   CRYSTAL GROWTH & DESIGN

Impact of surfactants on the crystal growth of amorphous celecoxib

(2013) Laura I. Mosquera-Giraldo et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Influence of Additives on the Properties of Nanodroplets Formed in Highly Supersaturated Aqueous Solutions of Ritonavir

(2013) Grace A. Ilevbare et al.   MOLECULAR PHARMACEUTICS

Hydrophobic Fluorescent Probes Introduce Artifacts into Single Molecule Tracking Experiments Due to Non-Specific Binding

(2013) Laura C. Zanetti-Domingues et al.   PLoS One

Vitamin E TPGS as a molecular biomaterial for drug delivery

(2012) Zhiping Zhang et al.   BIOMATERIALS

“Perfecting” WATERGATE: clean proton NMR spectra from aqueous solution

(2012) Ralph W. Adams et al.   CHEMICAL COMMUNICATIONS

Insights into the Role of Polymer-Surfactant Complexes in Drug Solubilisation/Stabilisation During Drug Release from Solid Dispersions

(2012) Sheng Qi et al.   PHARMACEUTICAL RESEARCH

Surface Structure of Sodium Dodecyl Sulfate Surfactant and Oil at the Oil-in-Water Droplet Liquid/Liquid Interface: A Manifestation of a Nonequilibrium Surface State

(2011) Hilton B. de Aguiar et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Molecular dynamics simulation of a polysorbate 80 micelle in water

(2011) Amir Amani et al.   Soft Matter

Study of Micellar Behavior of SDS and CTAB in Aqueous Media Containing Furosemide—A Cardiovascular Drug

(2010) S. Chauhan et al.   JOURNAL OF SOLUTION CHEMISTRY

Critical Micelle Concentration and HLB of the Sodium Oleate–Hexadecyltrimethylammonium Bromide Mixed System

(2010) Daniela B. Miraglia et al.   JOURNAL OF SURFACTANTS AND DETERGENTS

Possible reduction of effective thickness of intestinal unstirred water layer by particle drifting effect

(2009) Kiyohiko Sugano   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Investigation of the micellar properties of the tocopheryl polyethylene glycol succinate surfactants TPGS 400 and TPGS 1000 by steady state fluorometry

(2009) M. Sadoqi et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Stoichiometry and Physical Chemistry of Promiscuous Aggregate-Based Inhibitors

(2008) Kristin E. D. Coan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY