Thyme Oil and Thymol Counter Doxorubicin-Induced Hepatotoxicity via Modulation of Inflammation, Apoptosis, and Oxidative Stress

Cellular Mechanisms of Liver Fibrosis

(2021) Pragyan Acharya et al.   Frontiers in Pharmacology

Chemotherapeutic Drugs and Mitochondrial Dysfunction: Focus on Doxorubicin, Trastuzumab, and Sunitinib

(2018) Stefania Gorini et al.   Oxidative Medicine and Cellular Longevity

Gancao (Glycyrrhizae Radix) provides the main contribution to Shaoyao-Gancao decoction on enhancements of CYP3A4 and MDR1 expression via pregnane X receptor pathway in vitro

(2018) Dandan Feng et al.   BMC Complementary and Alternative Medicine

Cytotoxicity and molecular docking studies on phytosterols isolated from Polygonum hydropiper L

(2018) Muhammad Ayaz et al.   STEROIDS

Safety of herbal medicine use during chemotherapy in patients with ovarian cancer: a “bedside-to-bench” approach

(2017) Eran Ben-Arye et al.   MEDICAL ONCOLOGY

Newly Synthesized Doxorubicin Complexes with Selected Metals—Synthesis, Structure and Anti-Breast Cancer Activity

(2017) Agata Jabłońska-Trypuć et al.   MOLECULES

Carvacrol induces the apoptosis of pulmonary artery smooth muscle cells under hypoxia

(2016) Qianlong Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effects of thymol and carvacrol on T-helper cell subset cytokines and their main transcription factors in ovalbumin-immunized mice

(2016) Nasser Gholijani et al.   Journal of Immunotoxicology

Curcumin Ameliorates Furazolidone-Induced DNA Damage and Apoptosis in Human Hepatocyte L02 Cells by Inhibiting ROS Production and Mitochondrial Pathway

(2016) Chongshan Dai et al.   MOLECULES

Targeting Wnt/β-catenin pathway in hepatocellular carcinoma treatment

(2016) Valery Vilchez   WORLD JOURNAL OF GASTROENTEROLOGY

MicroRNA-186 targets Yes-associated protein 1 to inhibit Hippo signaling and tumorigenesis in hepatocellular carcinoma

(2016) TINGYAN RUAN et al.   Oncology Letters

Anti-emetic mechanisms of zingiber officinale against cisplatin induced emesis in the pigeon; behavioral and neurochemical correlates

(2015) Ihsan Ullah et al.   BMC Complementary and Alternative Medicine

Thymol attenuates inflammation in isoproterenol induced myocardial infarcted rats by inhibiting the release of lysosomal enzymes and downregulating the expressions of proinflammatory cytokines

(2015) Mohamed Fizur Nagoor Meeran et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Thymol and Carvacrol Prevent Doxorubicin-Induced Cardiotoxicity by Abrogation of Oxidative Stress, Inflammation, and Apoptosis in Rats

(2015) El-Sayed M. El-Sayed et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Thymol attenuates altered lipid metabolism in β-adrenergic agonist induced myocardial infarcted rats by inhibiting tachycardia, altered electrocardiogram, apoptosis and cardiac hypertrophy

(2015) Mohamed Fizur Nagoor Meeran et al.   Journal of Functional Foods

Induction of Caspase-9, Biochemical Assessment and Morphological Changes Caused by Apoptosis in Cancer Cells Treated with Goniothalamin Extracted from Goniothalamus macrophyllus

(2014) Aied Mohammed Alabsi et al.   Asian Pacific Journal of Cancer Prevention

Preventive Effect of Hydrazinocurcumin on Carcinogenesis of Diethylnitrosamine-induced Hepatocarcinoma in Male SD Rats

(2014) Ji-An Zhao et al.   Asian Pacific Journal of Cancer Prevention

Expression of bcl-2 and p53 in Induction of Esophageal Cancer Cell Apoptosis by ECRG2 in Combination with Cisplatin

(2014) Hai-Yan Song et al.   Asian Pacific Journal of Cancer Prevention

Thymol, a monoterpene phenolic derivative of cymene, abrogates mercury-induced oxidative stress resultant cytotoxicity and genotoxicity in hepatocarcinoma cells

(2014) Nishan B. Shettigar et al.   ENVIRONMENTAL TOXICOLOGY

Thymol attenuates allergic airway inflammation in ovalbumin (OVA)-induced mouse asthma

(2014) Ershun Zhou et al.   FITOTERAPIA

Doxorubicin induced apoptosis was potentiated by neferine in human lung adenocarcima, A549 cells

(2014) Paramasivan Poornima et al.   FOOD AND CHEMICAL TOXICOLOGY

Thymol and Carvacrol Prevent Cisplatin-Induced Nephrotoxicity by Abrogation of Oxidative Stress, Inflammation, and Apoptosis in Rats

(2014) El-Sayed EM et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Protective effect of the edible brown algaEcklonia stoloniferaon doxorubicin-induced hepatotoxicity in primary rat hepatocytes

(2014) Hyun Ah Jung et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

IHC Profiler: An Open Source Plugin for the Quantitative Evaluation and Automated Scoring of Immunohistochemistry Images of Human Tissue Samples

(2014) Frency Varghese et al.   PLoS One

Biochemical responses and mitochondrial mediated activation of apoptosis on long-term effect of aspartame in rat brain

(2014) Iyaswamy Ashok et al.   Redox Biology

Is Short-term Exercise a Therapeutic Tool for Improvement of Cardioprotection Against DOX-induced Cardiotoxicity? An Experimental Controlled Protocol in Rats

(2013) Javad Ashrafi et al.   Asian Pacific Journal of Cancer Prevention

Ameliorative effects of thyme and calendula extracts alone or in combination against aflatoxins-induced oxidative stress and genotoxicity in rat liver

(2013) Sekena H. Abdel-Aziem et al.   CYTOTECHNOLOGY

Anti-inflammatory effects of 27 selected terpenoid compounds tested through modulating Th1/Th2 cytokine secretion profiles using murine primary splenocytes

(2013) Chi-Mei Ku et al.   FOOD CHEMISTRY

Carvacrol ameliorates thioacetamide-induced hepatotoxicity by abrogation of oxidative stress, inflammation, and apoptosis in liver of Wistar rats

(2013) S Nafees et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Thymol Inhibits LPS-Stimulated Inflammatory Response via Down-Regulation of NF-κB and MAPK Signaling Pathways in Mouse Mammary Epithelial Cells

(2013) Dejie Liang et al.   INFLAMMATION

Thymol from Thymus quinquecostatus Celak. protects against tert-butyl hydroperoxide-induced oxidative stress in Chang cells

(2013) Yon-Suk Kim et al.   Journal of Natural Medicines

Effect of thymol and carvacrol feed supplementation on performance, antioxidant enzyme activities, fatty acid composition, digestive enzyme activities, and immune response in broiler chickens

(2013) H. Hashemipour et al.   POULTRY SCIENCE

Carvacrol suppresses the expression of inflammatory marker genes in D-galactosamine-hepatotoxic rats

(2013) Balakrishnan Aristatile et al.   Asian Pacific Journal of Tropical Medicine

Mitochondrial superoxide mediates doxorubicin-induced keratinocyte apoptosis through oxidative modification of ERK and Bcl-2 ubiquitination

(2012) Sudjit Luanpitpong et al.   BIOCHEMICAL PHARMACOLOGY

Vitamin E and telmisartan attenuates doxorubicin induced cardiac injury in rat through down regulation of inflammatory response

(2012) Najah Hadi et al.   BMC Cardiovascular Disorders

DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis

(2012) Wynand P. Roos et al.   CANCER LETTERS

Effects of Thymol and Carvacrol, Constituents ofThymus vulgarisL. Essential Oil, on the Inflammatory Response

(2012) Fernanda Carolina Fachini-Queiroz et al.   Evidence-based Complementary and Alternative Medicine

Histopathological effects of cisplatin, doxorubicin and 5-flurouracil (5-FU) on the liver of male albino rats

(2012) Hassan I El-Sayyad et al.   International Journal of Biological Sciences

Protective effects of thymol on altered plasma lipid peroxidation and nonenzymic antioxidants in isoproterenol-induced myocardial infarcted rats

(2012) Mohamed Fizur Nagoor Meeran et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Changes in mitochondrial redox state, membrane potential and calcium precede mitochondrial dysfunction in doxorubicin-induced cell death

(2011) Andrey V. Kuznetsov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Antimicrobial, Antioxidant, and Anti-Inflammatory Activities of Essential Oils from Five Selected Herbs

(2011) Mei-Lin TSAI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Cardioprotective Effects of Hesperetin against Doxorubicin-Induced Oxidative Stress and DNA Damage in Rat

(2011) P. P. Trivedi et al.   Cardiovascular Toxicology

IFCC primary reference procedures for the measurement of catalytic activity concentrations of enzymes at 37 °C. Part 9: Reference procedure for the measurement of catalytic concentration of alkaline phosphatase

(2011) Gerhard Schumann et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Essential Oils Composition and Antioxidant Properties of ThreeThymusSpecies

(2011) Hamzeh Amiri   Evidence-based Complementary and Alternative Medicine

Antioxidant properties of Thymus vulgaris oil against aflatoxin-induce oxidative stress in male rats

(2011) Aziza A. El-Nekeety et al.   TOXICON

Effect of doxorubicin on cytokine production by lymphocytes and the Th1/Th2 balance

(2010) R.V.T. Santos et al.   BIOMEDICINE & PHARMACOTHERAPY

Regioselective one-pot synthesis and anti-proliferative and apoptotic effects of some novel tetrazolo[1,5-a]pyrimidine derivatives

(2010) Ahmed M. Hussein et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Silymarin modulates doxorubicin-induced oxidative stress, Bcl-xL and p53 expression while preventing apoptotic and necrotic cell death in the liver

(2010) Nirav Patel et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Protective effect of Solanum torvum on doxorubicin-induced nephrotoxicity in rats

(2009) Mahalaxmi Mohan et al.   FOOD AND CHEMICAL TOXICOLOGY

The effect of doxorubicin on rats that received toxic and carcinogenic benzo(a)pyrene.

(2008) Didem Cosan et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Part I: Liver function in oncology: biochemistry and beyond

(2008) Kathryn M Field et al.   LANCET ONCOLOGY