Gancao (Glycyrrhizae Radix) provides the main contribution to Shaoyao-Gancao decoction on enhancements of CYP3A4 and MDR1 expression via pregnane X receptor pathway in vitro

Pharmacokinetic study of representative anti-oxidative compounds from Denshen-Chuanxiong-Honghua following oral administration in rats

(2017) Xianhua Zhang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The use of Chinese herbal medicine as an adjuvant therapy to reduce incidence of chronic hepatitis in colon cancer patients: A Taiwanese population-based cohort study

(2017) Tsai-Hui Lin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Complementary Chinese herbal medicine therapy improves survival of patients with gastric cancer in Taiwan: A nationwide retrospective matched-cohort study

(2017) Kuo-Feng Hung et al.   JOURNAL OF ETHNOPHARMACOLOGY

Safety of herbal medicine use during chemotherapy in patients with ovarian cancer: a “bedside-to-bench” approach

(2017) Eran Ben-Arye et al.   MEDICAL ONCOLOGY

MicroRNA-30c-1-3p is a silencer of the pregnane X receptor by targeting the 3′-untranslated region and alters the expression of its target gene cytochrome P450 3A4

(2016) Thaveechai Vachirayonstien et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Pretreatment of Shaoyao Gancao Decoction (芍药甘草汤) alters pharmacokinetics of intravenous paclitaxel in rats

(2016) Yang Wang et al.   Chinese Journal of Integrative Medicine

Mechanism-based inhibition of Alantolactone on human cytochrome P450 3A4 in vitro and activity of hepatic cytochrome P450 in mice

(2015) Chong-Zhen Qin et al.   JOURNAL OF ETHNOPHARMACOLOGY

In Vitro and in Vivo Inhibitory Effects of Glycyrrhetinic Acid in Mice and Human Cytochrome P450 3A4

(2015) Qiao-Li Lv et al.   International Journal of Environmental Research and Public Health

Survey of Human Oxidoreductases and Cytochrome P450 Enzymes Involved in the Metabolism of Xenobiotic and Natural Chemicals

(2014) Slobodan Rendic et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Nuclear receptors PXR and CAR: implications for drug metabolism regulation, pharmacogenomics and beyond

(2013) Xiaojuan Chai et al.   Expert Opinion on Drug Metabolism & Toxicology

Pharmacokinetic comparisons of different combinations of Shaoyao-Gancao-Decoction in rats: Simultaneous determination of ten active constituents by HPLC–MS/MS

(2013) Yang Wang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Effects of rikkunshito, a kampo medicine, on quality of life after proximal gastrectomy

(2013) Shutaro Gunji et al.   JOURNAL OF SURGICAL RESEARCH

Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1

(2013) Yue-Ming Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Sesamin: A Naturally Occurring Lignan Inhibits CYP3A4 by Antagonizing the Pregnane X Receptor Activation

(2012) Yun-Ping Lim et al.   Evidence-based Complementary and Alternative Medicine

Liquorice reduced cyclosporine bioavailability by activating P-glycoprotein and CYP 3A

(2012) Yu-Chi Hou et al.   FOOD CHEMISTRY

Absorption and Interaction of the Main Constituents from the Traditional Chinese Drug Pair Shaoyao-Gancao via a Caco-2 Cell Monolayer Model

(2012) Yan Chen et al.   MOLECULES

Pharmacokinetics of characteristic effective ingredients from individual and combination Shaoyao and Gancao treatement in rats using HPLC fingerprinting

(2011) Lan Shen et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Identification of novel pregnane X receptor activators from traditional Chinese medicines

(2011) Chunna Yu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Pharmacokinetic Comparisons of Albiflorin and Paeoniflorin after Oral Administration of Shaoyao-Gancao-Tang and Single Herb Paeony Decoction to Rats

(2011) Pingping Gan et al.   PLANTA MEDICA

Expression and distribution of CYP3A genes, CYP2B22, and MDR1, MRP1, MRP2, LRP efflux transporters in brain of control and rifampicin-treated pigs

(2009) Annalisa Nannelli et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Study on the pharmacokinetics drug-drug interaction potential ofglycyrrhiza uralensis, a traditional Chinese medicine, with lidocaine in rats

(2009) Jingcheng Tang et al.   PHYTOTHERAPY RESEARCH

Herbal medicine Shakuyaku-kanzo-to reduces paclitaxel-induced painful peripheral neuropathy in mice

(2008) Takao Hidaka et al.   EUROPEAN JOURNAL OF PAIN

The Efficacy of prophylactic Shakuyaku-Kanzo-to for myalgia and arthralgia following Carboplatin and Paclitaxel combination chemotherapy for non-small cell lung cancer

(2008) Tsutomu Yoshida et al.   SUPPORTIVE CARE IN CANCER

Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells

(2007) P Martin et al.   BRITISH JOURNAL OF PHARMACOLOGY