miR-155-5p in Extracellular Vesicles Derived from Choroid Plexus Epithelial Cells Promotes Autophagy and Inflammation to Aggravate Ischemic Brain Injury in Mice

Contribution of TRPC Channels in Neuronal Excitotoxicity Associated With Neurodegenerative Disease and Ischemic Stroke

(2021) Jaepyo Jeon et al.   Frontiers in Cell and Developmental Biology

Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

(2021) Valery L Feigin et al.   LANCET NEUROLOGY

Human extracellular vesicles and correlation with two clinical forms of toxoplasmosis

(2020) Allecineia Bispo da Cruz et al.   PLoS One

Advances in the molecular mechanisms of NLRP3 inflammasome activators and inactivators

(2020) Dongling Liu et al.   BIOCHEMICAL PHARMACOLOGY

Rheb1 protects against cisplatin-induced tubular cell death and acute kidney injury via maintaining mitochondrial homeostasis

(2020) Qingmiao Lu et al.   Cell Death & Disease

Treatment with AAV1-Rheb(S16H) provides neuroprotection in a mouse model of photothrombosis-induced ischemic stroke

(2020) Dongyeong Yoon et al.   NEUROREPORT

Exosome-Shuttled circSHOC2 from IPASs Regulates Neuronal Autophagy and Ameliorates Ischemic Brain Injury via the miR-7670-3p/SIRT1 Axis

(2020) Wanghao Chen et al.   Molecular Therapy-Nucleic Acids

A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis

(2020) Tailin He et al.   Acta Pharmaceutica Sinica B

A novel small molecular NLRP3 inflammasome inhibitor alleviates neuroinflammatory response following traumatic brain injury

(2019) Ram Kuwar et al.   Journal of Neuroinflammation

Angioneurins – Key regulators of blood–brain barrier integrity during hypoxic and ischemic brain injury

(2019) Reiner Kunze et al.   PROGRESS IN NEUROBIOLOGY

Accessing neuroinflammation sites: Monocyte/neutrophil-mediated drug delivery for cerebral ischemia

(2019) Jia Hou et al.   Science Advances

Extracellular vesicles as biomarkers and therapeutic targets for cancer

(2019) Fumihiko Urabe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Impact of extracellular vesicles on innate immunity

(2019) Zhizhao Chen et al.   Current Opinion in Organ Transplantation

MicroRNA-155 regulates Inflammatory Response in Ischemic Cerebral Tissues through autophagy

(2018) Yi Yang et al.   CURRENT NEUROVASCULAR RESEARCH

MiR-155-5p inhibits PDK1 and promotes autophagy via the mTOR pathway in cervical cancer

(2018) Fang Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Ginkgolide B ameliorates NLRP3 inflammasome activation after hypoxic-ischemic brain injury in the neonatal male rat

(2018) Aiming Chen et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

MicroRNA‑155 promotes ox‑LDL‑induced autophagy in human umbilical vein endothelial cells by targeting the PI3K/Akt/mTOR pathway

(2018) Shuangshuang Yin et al.   Molecular Medicine Reports

Neuroprotective nature of adipokine resistin in the early stages of focal cerebral ischemia in a stroke mouse model

(2018) Sedigheh Behrouzifar et al.   NEUROCHEMISTRY INTERNATIONAL

Exosome Therapy for Stroke

(2018) Jieli Chen et al.   STROKE

Diosgenin Glucoside Protects against Spinal Cord Injury by Regulating Autophagy and Alleviating Apoptosis

(2018) Xian-Bing Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exosomal miR-7 Mediates Bystander Autophagy in Lung after Focal Brain Irradiation in Mice

(2017) Shang Cai et al.   International Journal of Biological Sciences

Endothelial nitric oxide synthase inhibition triggers inflammatory responses in the brain of male rats exposed to ischemia-reperfusion injury

(2017) Rosaria Greco et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Irisin protects against neuronal injury induced by oxygen-glucose deprivation in part depends on the inhibition of ROS-NLRP3 inflammatory signaling pathway

(2017) Juan Peng et al.   MOLECULAR IMMUNOLOGY

MicroRNA-30e regulates neuroinflammation in MPTP model of Parkinson’s disease by targeting Nlrp3

(2017) Dongsheng Li et al.   Human Cell

Identification of a novel mechanism of blood–brain communication during peripheral inflammation via choroid plexus‐derived extracellular vesicles

(2016) Sriram Balusu et al.   EMBO Molecular Medicine

N-Myc Downstream-Regulated Gene 2 (Ndrg2) Is Involved in Ischemia–Hypoxia-Induced Astrocyte Apoptosis: a Novel Target for Stroke Therapy

(2016) Yu-Long Ma et al.   MOLECULAR NEUROBIOLOGY

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia-Ischemia

(2016) Daan R.M.G. Ophelders et al.   Stem Cells Translational Medicine

Influence of miR-155 on Cell Apoptosis in Rats with Ischemic Stroke: Role of the Ras Homolog Enriched in Brain (Rheb)/mTOR Pathway

(2016) Guoping Xing et al.   MEDICAL SCIENCE MONITOR

Defective mitophagy driven by dysregulation of rheb and KIF5B contributes to mitochondrial reactive oxygen species (ROS)-induced nod-like receptor 3 (NLRP3) dependent proinflammatory response and aggravates lipotoxicity

(2014) Sijun Yang et al.   Redox Biology

Melatonin Pretreatment Improves the Survival and Function of Transplanted Mesenchymal Stem Cells after Focal Cerebral Ischemia

(2013) Yaohui Tang et al.   CELL TRANSPLANTATION

Emerging mechanisms of disrupted cellular signaling in brain ischemia

(2011) Michael Tymianski   NATURE NEUROSCIENCE

IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction

(2009) M. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA