Discovery of highly reactive self-splicing group II introns within the mitochondrial genomes of human pathogenic fungi

Small-molecule inhibitors for the Prp8 intein as antifungal agents

(2021) Zhong Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Review of T-2307, an Investigational Agent That Causes Collapse of Fungal Mitochondrial Membrane Potential

(2021) Nathan P. Wiederhold   Journal of Fungi

Bacterial group II intron genomic neighborhoods reflect survival strategies: hiding and hijacking

(2020) Justin Waldern et al.   MOLECULAR BIOLOGY AND EVOLUTION

Group II intron as cold sensor for self-preservation and bacterial conjugation

(2020) Xiaolong Dong et al.   NUCLEIC ACIDS RESEARCH

Structural and functional conservation of the programmed −1 ribosomal frameshift signal of SARS coronavirus 2 (SARS-CoV-2)

(2020) Jamie A. Kelly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The potential of respiration inhibition as a new approach to combat human fungal pathogens

(2019) Lucian Duvenage et al.   CURRENT GENETICS

Host resistance factor SLC11A1 restricts Salmonella growth through magnesium deprivation

(2019) Olivier Cunrath et al.   SCIENCE

Fantastic yeasts and where to find them: the hidden diversity of dimorphic fungal pathogens

(2019) Marley C Caballero Van Dyke et al.   CURRENT OPINION IN MICROBIOLOGY

Worldwide emergence of resistance to antifungal drugs challenges human health and food security

(2018) Matthew C. Fisher et al.   SCIENCE

Small molecules that target group II introns are potent antifungal agents

(2018) Olga Fedorova et al.   Nature Chemical Biology

Optimal molecular crowding accelerates group II intron folding and maximizes catalysis

(2018) Bishnu P. Paudel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The antifungal pipeline: a reality check

(2017) John R. Perfect   NATURE REVIEWS DRUG DISCOVERY

Structural Insights into the Mechanism of Group II Intron Splicing

(2017) Chen Zhao et al.   TRENDS IN BIOCHEMICAL SCIENCES

Antifungal therapeutics for dimorphic fungal pathogens

(2016) Kristie D. Goughenour et al.   Virulence

Perspective on Coccidioidomycosis and Histoplasmosis

(2014) Kenneth S. Knox   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Molecular Crowding Accelerates Ribozyme Docking and Catalysis

(2014) Bishnu P. Paudel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular-crowding effects on single-molecule RNA folding/unfolding thermodynamics and kinetics

(2014) N. F. Dupuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visualizing Group II Intron Catalysis through the Stages of Splicing

(2012) Marco Marcia et al.   CELL

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

A 971-bp insertion in the rns gene is associated with mitochondrial hypovirulence in a strain of Cryphonectria parasitica isolated from nature

(2011) Dipnath Baidyaroy et al.   FUNGAL GENETICS AND BIOLOGY

Database for bacterial group II introns

(2011) M. A. Candales et al.   NUCLEIC ACIDS RESEARCH

Recurrent insertion of 5'-terminal nucleotides and loss of the branchpoint motif in lineages of group II introns inserted in mitochondrial preribosomal RNAs

(2011) C.-F. Li et al.   RNA

The tertiary structure of group II introns: implications for biological function and evolution

(2010) Anna Marie Pyle   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Dual roles for the Mss116 cofactor during splicing of the ai5γ group II intron

(2010) Nora Zingler et al.   NUCLEIC ACIDS RESEARCH

Group II Introns: Mobile Ribozymes that Invade DNA

(2010) A. M. Lambowitz et al.   Cold Spring Harbor Perspectives in Biology

Structural Basis for Stabilization of the Tau Pre-mRNA Splicing Regulatory Element by Novantrone (Mitoxantrone)

(2009) Suxin Zheng et al.   CHEMISTRY & BIOLOGY

Mitoxantrone Analogues as Ligands for a Stem−Loop Structure of Tau Pre-mRNA

(2009) Yang Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

In Vitro and In Vivo Antifungal Activities of T-2307, a Novel Arylamidine

(2008) J. Mitsuyama et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY