The neuropathology of autism: A systematic review of post-mortem studies of autism and related disorders

Exploring the mechanisms underlying excitation/inhibition imbalance in human iPSC-derived models of ASD

(2020) Lorenza Culotta et al.   Molecular Autism

Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

(2020) Stavros Trakoshis et al.   eLife

Postnatal development and maturation of layer 1 in the lateral prefrontal cortex and its disruption in autism

(2019) Iris Margalit Trutzer et al.   Acta Neuropathologica Communications

Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue

(2019) Chloe C Y Wong et al.   HUMAN MOLECULAR GENETICS

Revisiting the excitation/Inhibition Imbalance Hypothesis of ASD Through A Clinical Lens

(2019) Russell G Port et al.   BRITISH JOURNAL OF RADIOLOGY

Large-scale analyses of the relationship between sex, age and intelligence quotient heterogeneity and cortical morphometry in autism spectrum disorder

(2019) Saashi A. Bedford et al.   MOLECULAR PSYCHIATRY

Somatic LINE-1 retrotransposition in cortical neurons and non-brain tissues of Rett patients and healthy individuals

(2019) Boxun Zhao et al.   PLoS Genetics

Commonality in dysregulated expression of gene sets in cortical brains of individuals with autism, schizophrenia, and bipolar disorder

(2019) Jinting Guan et al.   Translational Psychiatry

Increased Expression of miR‐155p5 in Amygdala of Children With Autism Spectrum Disorder

(2019) Khulood Abdullah Almehmadi et al.   Autism Research

New insights on synaptic dysfunction in neuropsychiatric disorders

(2019) Gladys Lima Caldeira et al.   CURRENT OPINION IN NEUROBIOLOGY

Profiling allele-specific gene expression in brains from individuals with autism spectrum disorder reveals preferential minor allele usage

(2019) Changhoon Lee et al.   NATURE NEUROSCIENCE

Increased expression of BDNF mRNA in the frontal cortex of autistic patients

(2018) Gilles Maussion et al.   BEHAVIOURAL BRAIN RESEARCH

Cerebellar Volume in Autism: Literature Meta-analysis and Analysis of the Autism Brain Imaging Data Exchange Cohort

(2018) Nicolas Traut et al.   BIOLOGICAL PSYCHIATRY

Are dopamine receptor and transporter changes in Rett syndrome reflected in Mecp2-deficient mice?

(2018) Dean F. Wong et al.   EXPERIMENTAL NEUROLOGY

5-Hydroxymethylcytosine alterations in the human postmortem brains of autism spectrum disorder

(2018) Ying Cheng et al.   HUMAN MOLECULAR GENETICS

Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex

(2018) Matthew Schwede et al.   Journal of Neurodevelopmental Disorders

Total RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M4Muscarinic Receptor as a Novel Therapeutic Target

(2018) Rocco G. Gogliotti et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The ASD Living Biology: from cell proliferation to clinical phenotype

(2018) Eric Courchesne et al.   MOLECULAR PSYCHIATRY

Allele-specific expression in a family quartet with autism reveals mono-to-biallelic switch and novel transcriptional processes of autism susceptibility genes

(2018) Chun-Yen Lin et al.   Scientific Reports

Evaluation of the Social Motivation Hypothesis of Autism

(2018) Caitlin C. Clements et al.   JAMA Psychiatry

Diffusion-weighted imaging evidence of altered white matter development from late childhood to early adulthood in Autism Spectrum Disorder

(2018) Fikret Işık Karahanoğlu et al.   NeuroImage-Clinical

Opposite development of short- and long-range anterior cingulate pathways in autism

(2018) Basilis Zikopoulos et al.   ACTA NEUROPATHOLOGICA

Synaptic dysfunction in neurodegenerative and neurodevelopmental diseases: an overview of induced pluripotent stem-cell-based disease models

(2018) Era Taoufik et al.   Open Biology

Solving for X: Evidence for sex-specific autism biomarkers across multiple transcriptomic studies

(2018) Samuel C. Lee et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Widespread RNA editing dysregulation in brains from autistic individuals

(2018) Stephen S. Tran et al.   NATURE NEUROSCIENCE

Effect of age and autism spectrum disorder on oxytocin receptor density in the human basal forebrain and midbrain

(2018) Sara M. Freeman et al.   Translational Psychiatry

Modeling Inflammation in Autism Spectrum Disorders Using Stem Cells

(2018) Beatriz C. Freitas et al.   Frontiers in Pediatrics

The contribution of [1H] magnetic resonance spectroscopy to the study of excitation-inhibition in autism

(2018) Laura A. Ajram et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Neurobiological bases of autism-epilepsy comorbidity: a focus on excitation/inhibition imbalance

(2017) Yuri Bozzi et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Protracted dendritic growth in the typically developing human amygdala and increased spine density in young ASD brains

(2017) R.K. Weir et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

(2017) Daniel J Weiner et al.   NATURE GENETICS

Autism Spectrum Disorder in Fragile X Syndrome: Cooccurring Conditions and Current Treatment

(2017) Walter E. Kaufmann et al.   PEDIATRICS

Disruption of melatonin synthesis is associated with impaired 14-3-3 and miR-451 levels in patients with autism spectrum disorders

(2017) Cécile Pagan et al.   Scientific Reports

Possible sexually dimorphic role of miRNA and other sncRNA in ASD brain

(2017) Cynthia M. Schumann et al.   Molecular Autism

Altered expression of histamine signaling genes in autism spectrum disorder

(2017) C Wright et al.   Translational Psychiatry

Shifting brain inhibitory balance and connectivity of the prefrontal cortex of adults with autism spectrum disorder

(2017) L A Ajram et al.   Translational Psychiatry

Variation in Gene Expression in Autism Spectrum Disorders: An Extensive Review of Transcriptomic Studies

(2017) Ashley Ansel et al.   Frontiers in Neuroscience

Primary olfactory cortex in autism and epilepsy: increased glial cells in autism

(2016) David A. Menassa et al.   BRAIN PATHOLOGY

Histone Acetylome-wide Association Study of Autism Spectrum Disorder

(2016) Wenjie Sun et al.   CELL

Brain GABA levels across psychiatric disorders: A systematic literature review and meta-analysis of1H-MRS studies

(2016) Remmelt R. Schür et al.   HUMAN BRAIN MAPPING

Exploiting aberrant mRNA expression in autism for gene discovery and diagnosis

(2016) Jinting Guan et al.   HUMAN GENETICS

mGlu5positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome

(2016) Rocco G. Gogliotti et al.   HUMAN MOLECULAR GENETICS

Imaging sex/gender and autism in the brain: Etiological implications

(2016) Meng-Chuan Lai et al.   JOURNAL OF NEUROSCIENCE RESEARCH

High resolution metabolomic analysis of ASD human brain uncovers novel biomarkers of disease

(2016) Stewart F. Graham et al.   Metabolomics

Genome-wide changes in lncRNA, splicing and regional gene expression patterns in autism

(2016) Neelroop N. Parikshak et al.   NATURE

Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder

(2016) Ye E Wu et al.   NATURE NEUROSCIENCE

Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome

(2016) Risa Kashima et al.   Science Signaling

Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders

(2016) Donna M. Werling et al.   Nature Communications

Blood–brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders

(2016) Maria Fiorentino et al.   Molecular Autism

Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome

(2016) Risa Kashima et al.   Science Signaling

Elevated GFAP Protein in Anterior Cingulate Cortical White Matter in Males With Autism Spectrum Disorder

(2015) Jessica D. Crawford et al.   Autism Research

Decreased expression of mGluR5 within the dorsolateral prefrontal cortex in autism and increased microglial number in mGluR5 knockout mice: Pathophysiological and neurobehavioral implications

(2015) Gursharan Chana et al.   BRAIN BEHAVIOR AND IMMUNITY

Dysregulated iron metabolism in the choroid plexus in fragile X-associated tremor/ataxia syndrome

(2015) Jeanelle Ariza et al.   BRAIN RESEARCH

Specific Regional and Age-Related Small Noncoding RNA Expression Patterns Within Superior Temporal Gyrus of Typical Human Brains Are Less Distinct in Autism Brains

(2015) Boryana Stamova et al.   JOURNAL OF CHILD NEUROLOGY

Altered mRNA Levels of Glucocorticoid Receptor, Mineralocorticoid Receptor, and Co-Chaperones (FKBP5 and PTGES3) in the Middle Frontal Gyrus of Autism Spectrum Disorder Subjects

(2015) Neil Patel et al.   MOLECULAR NEUROBIOLOGY

From the genetic architecture to synaptic plasticity in autism spectrum disorder

(2015) Thomas Bourgeron   NATURE REVIEWS NEUROSCIENCE

Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms

(2015) Alissa M. D’Gama et al.   NEURON

A Comparison of Structural Brain Imaging Findings in Autism Spectrum Disorder and Attention-Deficit Hyperactivity Disorder

(2015) Chase C. Dougherty et al.   NEUROPSYCHOLOGY REVIEW

Head circumference and brain size in autism spectrum disorder: A systematic review and meta-analysis

(2015) Roberto Sacco et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

GABA receptor subunit distribution and FMRP–mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism

(2015) S. Hossein Fatemi et al.   SCHIZOPHRENIA RESEARCH

Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders

(2015) Bradley P. Ander et al.   Molecular Autism

Investigation of sex differences in the expression of RORA and its transcriptional targets in the brain as a potential contributor to the sex bias in autism

(2015) Valerie W Hu et al.   Molecular Autism

Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid

(2015) Chiara Nicolini et al.   Acta Neuropathologica Communications

Anatomical Abnormalities in Autism?

(2014) Shlomi Haar et al.   CEREBRAL CORTEX

The apoptotic perspective of autism

(2014) Hongen Wei et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Dysregulation of the IGF-I/PI3K/AKT/mTOR signaling pathway in autism spectrum disorders

(2014) Jianling Chen et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Neuropathology of the Anterior Midcingulate Cortex in Young Children With Autism

(2014) Neha Uppal et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Zinc finger protein 804A (ZNF804A) and verbal deficits in individuals with autism

(2014) Ayyappan Anitha et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Increased CYFIP1 dosage alters cellular and dendritic morphology and dysregulates mTOR

(2014) A Oguro-Ando et al.   MOLECULAR PSYCHIATRY

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

The Cerebellum, Sensitive Periods, and Autism

(2014) Samuel S.-H. Wang et al.   NEURON

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

(2014) Guomei Tang et al.   NEURON

RELN-expressing neuron density in layer I of the superior temporal lobe is similar in human brains with autism and in age-matched controls

(2014) Jasmin Camacho et al.   NEUROSCIENCE LETTERS

The dual role of astrocyte activation and reactive gliosis

(2014) Milos Pekny et al.   NEUROSCIENCE LETTERS

Patches of Disorganization in the Neocortex of Children with Autism

(2014) Rich Stoner et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neuropathology of 22q11 Deletion Syndrome in an Infant

(2014) Peter Wu et al.   PEDIATRIC AND DEVELOPMENTAL PATHOLOGY

Regional Alterations in Purkinje Cell Density in Patients with Autism

(2014) Jerry Skefos et al.   PLoS One

Stereological Study of Amygdala Glial Populations in Adolescents and Adults with Autism Spectrum Disorder

(2014) John T. Morgan et al.   PLoS One

Cerebellar Oxidative DNA Damage and Altered DNA Methylation in the BTBR T+tf/J Mouse Model of Autism and Similarities with Human Post Mortem Cerebellum

(2014) Svitlana Shpyleva et al.   PLoS One

Categorical diagnosis: a fatal flaw for autism research?

(2014) Eric B. London   TRENDS IN NEUROSCIENCES

Pharmacogenetic Inhibition of eIF4E-Dependent Mmp9 mRNA Translation Reverses Fragile X Syndrome-like Phenotypes

(2014) Christos G. Gkogkas et al.   Cell Reports

Exon resequencing of H3K9 methyltransferase complex genes, EHMT1, EHTM2 and WIZ, in Japanese autism subjects

(2014) Shabeesh Balan et al.   Molecular Autism

Dysregulation of estrogen receptor beta (ERβ), aromatase (CYP19A1), and ER co-activators in the middle frontal gyrus of autism spectrum disorder subjects

(2014) Amanda Crider et al.   Molecular Autism

Altered glial marker expression in autistic post-mortem prefrontal cortex and cerebellum

(2014) Catherine Edmonson et al.   Molecular Autism

Ubiquitin-proteasome dependent degradation of GABAAα1 in autism spectrum disorder

(2014) Amanda Crider et al.   Molecular Autism

N-ethylmaleimide-sensitive factor interacts with the serotonin transporter and modulates its trafficking: implications for pathophysiology in autism

(2014) Keiko Iwata et al.   Molecular Autism

Proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins

(2014) Jantine AC Broek et al.   Molecular Autism

Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum

(2014) A Zhubi et al.   Translational Psychiatry

Brain-region–specific alterations of the trajectories of neuronal volume growth throughout the lifespan in autism

(2014) Jerzy Wegiel et al.   Acta Neuropathologica Communications

Reduced Serotonin Receptor Subtypes in a Limbic and a Neocortical Region in Autism

(2013) Adrian Oblak et al.   Autism Research

Heparan sulfate deficiency in autistic postmortem brain tissue from the subventricular zone of the lateral ventricles

(2013) Brandon L. Pearson et al.   BEHAVIOURAL BRAIN RESEARCH

Microglial Dysregulation in Psychiatric Disease

(2013) Luciana Romina Frick et al.   Clinical & Developmental Immunology

Subventricular zone cytoarchitecture changes in Autism

(2013) Prasanti Kotagiri et al.   Developmental Neurobiology

Segregation of the human medial prefrontal cortex in social cognition

(2013) Danilo Bzdok et al.   Frontiers in Human Neuroscience

Altered neural connectivity in excitatory and inhibitory cortical circuits in autism

(2013) Basilis Zikopoulos et al.   Frontiers in Human Neuroscience

Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders

(2013) Li Zhu et al.   HUMAN MOLECULAR GENETICS

Common genetic variants on 1p13.2 associate with risk of autism

(2013) K Xia et al.   MOLECULAR PSYCHIATRY

Common DNA methylation alterations in multiple brain regions in autism

(2013) C Ladd-Acosta et al.   MOLECULAR PSYCHIATRY

Genes for endosomal NHE6 and NHE9 are misregulated in autism brains

(2013) M Schwede et al.   MOLECULAR PSYCHIATRY

From promises to practical strategies in epigenetic epidemiology

(2013) Jonathan Mill et al.   NATURE REVIEWS GENETICS

Mitochondrial abnormalities in temporal lobe of autistic brain

(2013) Guomei Tang et al.   NEUROBIOLOGY OF DISEASE

Rare Inherited Variation in Autism: Beginning to See the Forest and a Few Trees

(2013) Jason L. Stein et al.   NEURON

Age-Dependent Decrease and Alternative Splicing of Methionine Synthase mRNA in Human Cerebral Cortex and an Accelerated Decrease in Autism

(2013) Christina R. Muratore et al.   PLoS One

Genome-wide identification of transcriptional targets of RORA reveals direct regulation of multiple genes associated with autism spectrum disorder

(2013) Tewarit Sarachana et al.   Molecular Autism

Expression of non-protein-coding antisense RNAs in genomic regions related to autism spectrum disorders

(2013) Dmitry Velmeshev et al.   Molecular Autism

Phosphorylated fragile X mental retardation protein at serine 499, is reduced in cerebellar vermis and superior frontal cortex of subjects with autism: implications for fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling

(2013) Øyvind G Rustan et al.   Molecular Autism

Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?

(2013) Talakad G Lohith et al.   Molecular Autism

Impairment of fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling and its downstream cognates ras-related C3 botulinum toxin substrate 1, amyloid beta A4 precursor protein, striatal-enriched protein tyrosine phosphatase, and homer 1, in autism: a postmortem study in cerebellar vermis and superior frontal cortex

(2013) S Fatemi et al.   Molecular Autism

Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism

(2013) Chie Shimmura et al.   Molecular Autism

Transcriptional regulation of the MET receptor tyrosine kinase gene by MeCP2 and sex-specific expression in autism and Rett syndrome

(2013) J T Plummer et al.   Translational Psychiatry

Complex epigenetic regulation of Engrailed-2 (EN-2) homeobox gene in the autism cerebellum

(2013) S J James et al.   Translational Psychiatry

Downregulation of the Expression of Mitochondrial Electron Transport Complex Genes in Autism Brains

(2012) Ayyappan Anitha et al.   BRAIN PATHOLOGY

Abnormal microglial–neuronal spatial organization in the dorsolateral prefrontal cortex in autism

(2012) John T. Morgan et al.   BRAIN RESEARCH

Levels of select PCB and PBDE congeners in human postmortem brain reveal possible environmental involvement in 15q11-q13 duplication autism spectrum disorder

(2012) Michelle M. Mitchell et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Aberrant Expression of Long Noncoding RNAs in Autistic Brain

(2012) Mark N. Ziats et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Altered Balance of Proteolytic Isoforms of Pro-Brain-Derived Neurotrophic Factor in Autism

(2012) Kristine L.P. Garcia et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Dephosphorylation-Induced Ubiquitination and Degradation of FMRP in Dendrites: A Role in Immediate Early mGluR-Stimulated Translation

(2012) V. C. Nalavadi et al.   JOURNAL OF NEUROSCIENCE

De novo mutations revealed by whole-exome sequencing are strongly associated with autism

(2012) Stephan J. Sanders et al.   NATURE

A Noncoding RNA Antisense to Moesin at 5p14.1 in Autism

(2012) T. Kerin et al.   Science Translational Medicine

Age-Dependent Brain Gene Expression and Copy Number Anomalies in Autism Suggest Distinct Pathological Processes at Young Versus Mature Ages

(2012) Maggie L. Chow et al.   PLoS Genetics

Brain region-specific altered expression and association of mitochondria-related genes in autism

(2012) Ayyappan Anitha et al.   Molecular Autism

Dystrophic Serotonin Axons in Postmortem Brains from Young Autism Patients

(2011) Efrain C. Azmitia et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Metabotropic Glutamate Receptor 5 Upregulation in Children with Autism is Associated with Underexpression of Both Fragile X Mental Retardation Protein and GABAA Receptor Beta 3 in Adults with Autism

(2011) S. Hossein Fatemi et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Epigenetic Signatures of Autism

(2011) Hennady P. Shulha   ARCHIVES OF GENERAL PSYCHIATRY

Altered posterior cingulate cortical cyctoarchitecture, but normal density of neurons and interneurons in the posterior cingulate cortex and fusiform gyrus in autism

(2011) Adrian L. Oblak et al.   Autism Research

Elevated Transcription Factor Specificity Protein 1 in Autistic Brains Alters the Expression of Autism Candidate Genes

(2011) Ismail Thanseem et al.   BIOLOGICAL PSYCHIATRY

The protocadherins, PCDHB1 and PCDH7, are regulated by MeCP2 in neuronal cells and brain tissues: implication for pathogenesis of Rett syndrome

(2011) Kunio Miyake et al.   BMC NEUROSCIENCE

Neuron Number and Size in Prefrontal Cortex of Children With Autism

(2011) Eric Courchesne et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

FMR1 premutation and full mutation molecular mechanisms related to autism

(2011) Randi Hagerman et al.   Journal of Neurodevelopmental Disorders

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

(2011) Irina Voineagu et al.   NATURE

Increased serotonin axons (immunoreactive to 5-HT transporter) in postmortem brains from young autism donors

(2011) Efrain C. Azmitia et al.   NEUROPHARMACOLOGY

A systematic review and meta-analysis of the fMRI investigation of autism spectrum disorders

(2011) Ruth C.M. Philip et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Association of Transcription Factor Gene LMX1B with Autism

(2011) Ismail Thanseem et al.   PLoS One

Increased copy number for methylated maternal 15q duplications leads to changes in gene and protein expression in human cortical samples

(2011) Haley A Scoles et al.   Molecular Autism

Decreased expression of axon-guidance receptors in the anterior cingulate cortex in autism

(2011) Shiro Suda et al.   Molecular Autism

Dysregulation of fragile × mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of individuals with autism: a postmortem brain study

(2011) S Hossein Fatemi et al.   Molecular Autism

Neuropathologic features in the hippocampus and cerebellum of three older men with fragile X syndrome

(2011) Claudia M Greco et al.   Molecular Autism

Microglial Activation and Increased Microglial Density Observed in the Dorsolateral Prefrontal Cortex in Autism

(2010) John T. Morgan et al.   BIOLOGICAL PSYCHIATRY

Downstream targets of methyl CpG binding protein 2 and their abnormal expression in the frontal cortex of the human Rett syndrome brain

(2010) Joanne H Gibson et al.   BMC NEUROSCIENCE

von Economo neurons in autism: A stereologic study of the frontoinsular cortex in children

(2010) Micaela Santos et al.   BRAIN RESEARCH

Brain Region-Specific Changes in Oxidative Stress and Neurotrophin Levels in Autism Spectrum Disorders (ASD)

(2010) Elizabeth M. Sajdel-Sulkowska et al.   CEREBELLUM

Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain

(2010) AnhThu Nguyen et al.   FASEB JOURNAL

Changes in Prefrontal Axons May Disrupt the Network in Autism

(2010) B. Zikopoulos et al.   JOURNAL OF NEUROSCIENCE

Replication study of Japanese cohorts supports the role of STX1A in autism susceptibility

(2010) Kazuhiko Nakamura et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Forced Expression of LIM Homeodomain Transcription Factor 1b Enhances Differentiation of Mouse Embryonic Stem Cells into Serotonergic Neurons

(2010) Virginie Dolmazon et al.   STEM CELLS AND DEVELOPMENT

Parvalbumin-, calbindin-, and calretinin-immunoreactive hippocampal interneuron density in autism

(2009) Y. A. Lawrence et al.   ACTA NEUROLOGICA SCANDINAVICA

Decreased GABAAreceptors and benzodiazepine binding sites in the anterior cingulate cortex in autism

(2009) A. Oblak et al.   Autism Research

Decreased GAD65 mRNA levels in select subpopulations of neurons in the cerebellar dentate nuclei in autism: an in situ hybridization study

(2009) Jane Yip et al.   Autism Research

Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

(2009) Jeffrey J. Hutsler et al.   BRAIN RESEARCH

Increase in Cerebellar Neurotrophin-3 and Oxidative Stress Markers in Autism

(2009) Elizabeth M. Sajdel-Sulkowska et al.   CEREBELLUM

miR-155: On the Crosstalk Between Inflammation and Cancer

(2009) Esmerina Tili et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Phenotypic spectrum associated with de novo and inherited deletions and duplications at 16p11.2 in individuals ascertained for diagnosis of autism spectrum disorder

(2009) B. A. Fernandez et al.   JOURNAL OF MEDICAL GENETICS

Density of cerebellar basket and stellate cells in autism: Evidence for a late developmental loss of Purkinje cells

(2009) Elizabeth R. Whitney et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Motivation and cognitive control in the human prefrontal cortex

(2009) Frédérique Kouneiher et al.   NATURE NEUROSCIENCE

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

(2009) Christopher A. Chapleau et al.   NEUROBIOLOGY OF DISEASE

Cathepsin D and apoptosis related proteins are elevated in the brain of autistic subjects

(2009) A.M. Sheikh et al.   NEUROSCIENCE

Epidemiology of Pervasive Developmental Disorders

(2009) Eric Fombonne   PEDIATRIC RESEARCH

The principled control of false positives in neuroimaging

(2009) Craig M. Bennett et al.   Social Cognitive and Affective Neuroscience

Management of a twenty-first century brain bank: experience in the BrainNet Europe consortium

(2008) Jeanne E. Bell et al.   ACTA NEUROPATHOLOGICA

MECP2promoter methylation and X chromosome inactivation in autism

(2008) Raman P. Nagarajan et al.   Autism Research

Neurons in the fusiform gyrus are fewer and smaller in autism

(2008) Imke A. J. van Kooten et al.   BRAIN

Morphological features of the medial superior olive in autism

(2008) Randy J. Kulesza et al.   BRAIN RESEARCH

Expression of GABAB Receptors Is Altered in Brains of Subjects with Autism

(2008) S. Hossein Fatemi et al.   CEREBELLUM

Neuropathologic Features in Adults with 22q11.2 Deletion Syndrome

(2008) T. R. Kiehl et al.   CEREBRAL CORTEX

Methyl-CpG-binding protein 2 polymorphisms and vulnerability to autism

(2008) C. S. Loat et al.   GENES BRAIN AND BEHAVIOR

Reciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autism

(2008) Susan E. Swanberg et al.   HUMAN MOLECULAR GENETICS

Altered calcium homeostasis in autism-spectrum disorders: evidence from biochemical and genetic studies of the mitochondrial aspartate/glutamate carrier AGC1

(2008) L Palmieri et al.   MOLECULAR PSYCHIATRY

Involvement of the PRKCB1 gene in autistic disorder: significant genetic association and reduced neocortical gene expression

(2008) C Lintas et al.   MOLECULAR PSYCHIATRY

SLC25A12 expression is associated with neurite outgrowth and is upregulated in the prefrontal cortex of autistic subjects

(2008) A-M Lepagnol-Bestel et al.   MOLECULAR PSYCHIATRY

Functional organization of the transcriptome in human brain

(2008) Michael C Oldham et al.   NATURE NEUROSCIENCE

Immune transcriptome alterations in the temporal cortex of subjects with autism

(2008) Krassimira Garbett et al.   NEUROBIOLOGY OF DISEASE

Heterogeneous dysregulation of microRNAs across the autism spectrum

(2008) Kawther Abu-Elneel et al.   NEUROGENETICS

Expression of astrocytic markers aquaporin 4 and connexin 43 is altered in brains of subjects with autism

(2008) S. Hossein Fatemi et al.   SYNAPSE

Towards a neuroanatomy of autism: A systematic review and meta-analysis of structural magnetic resonance imaging studies

(2007) Andrew C. Stanfield et al.   EUROPEAN PSYCHIATRY

Brain micro-ecologies: neural stem cell niches in the adult mammalian brain

(2007) P. A Riquelme et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES