Translocator Protein Regulate Polarization Phenotype Transformation of Microglia after Cerebral Ischemia–reperfusion Injury

Stroke in China: advances and challenges in epidemiology, prevention, and management

(2019) Simiao Wu et al.   LANCET NEUROLOGY

A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis

(2019) Erik Nutma et al.   BRAIN

TSPO Modulates IL-4-Induced Microglia/Macrophage M2 Polarization via PPAR-γ Pathway

(2019) Dandan Zhou et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Custom-Made Ceria Nanoparticles Show a Neuroprotective Effect by Modulating Phenotypic Polarization of the Microglia

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Koumine Attenuates Neuroglia Activation and Inflammatory Response to Neuropathic Pain

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Intranasal delivery of a Fas-blocking peptide attenuates Fas-mediated apoptosis in brain ischemia

(2018) Irfan Ullah et al.   Scientific Reports

The P2X7 Receptor in Infection and Inflammation

(2017) Francesco Di Virgilio et al.   IMMUNITY

A translocator protein 18 kDa agonist protects against cerebral ischemia/reperfusion injury

(2017) Han-Dong Li et al.   Journal of Neuroinflammation

Reconceptualization of translocator protein as a biomarker of neuroinflammation in psychiatry

(2017) T Notter et al.   MOLECULAR PSYCHIATRY

Electroacupuncture Suppresses the NF-κB Signaling Pathway by Upregulating Cylindromatosis to Alleviate Inflammatory Injury in Cerebral Ischemia/Reperfusion Rats

(2017) Jin Jiang et al.   Frontiers in Molecular Neuroscience

Sinomenine enhances microglia M2 polarization and attenuates inflammatory injury in intracerebral hemorrhage

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Augmented expression of TSPO after intracerebral hemorrhage: a role in inflammation?

(2016) Frederick Bonsack et al.   Journal of Neuroinflammation

Functions and mechanisms of microglia/macrophages in neuroinflammation and neurogenesis after stroke

(2016) Xiao-Yi Xiong et al.   PROGRESS IN NEUROBIOLOGY

Lentiviral-Mediated Overexpression of the 18 kDa Translocator Protein (TSPO) in the Hippocampal Dentate Gyrus Ameliorates LPS-Induced Cognitive Impairment in Mice

(2016) Wei Wang et al.   Frontiers in Pharmacology

Acute Stroke Intervention

(2015) Shyam Prabhakaran et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis

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Rosiglitazone Promotes White Matter Integrity and Long-Term Functional Recovery After Focal Cerebral Ischemia

(2015) Lijuan Han et al.   STROKE

Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: Assessed with [11C]-PBR28

(2015) Nicole R. Zürcher et al.   NeuroImage-Clinical

The 18 kDa Translocator Protein, Microglia and Neuroinflammation

(2014) Guo-Jun Liu et al.   BRAIN PATHOLOGY

Translocator Protein 18 kDa Negatively Regulates Inflammation in Microglia

(2014) Keun-Ryung Bae et al.   Journal of Neuroimmune Pharmacology

Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis

(2014) Marcus Karlstetter et al.   Journal of Neuroinflammation

Inhibition of mammalian target of rapamycin improves neurobehavioral deficit and modulates immune response after intracerebral hemorrhage in rat

(2014) Qin Lu et al.   Journal of Neuroinflammation

Macrophagic and microglial responses after focal traumatic brain injury in the female rat

(2014) L Turtzo et al.   Journal of Neuroinflammation

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed

(2014) Jonathan D Cherry et al.   Journal of Neuroinflammation

Sinomenine inhibits microglia activation and attenuates brain injury in intracerebral hemorrhage

(2014) Zhao Yang et al.   MOLECULAR IMMUNOLOGY

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

TNF and Increased Intracellular Iron Alter Macrophage Polarization to a Detrimental M1 Phenotype in the Injured Spinal Cord

(2014) Antje Kroner et al.   NEURON

The human side of microglia

(2014) Amy M. Smith et al.   TRENDS IN NEUROSCIENCES

Positron emission tomography and functional characterization of a complete PBR/TSPO knockout

(2014) Richard B. Banati et al.   Nature Communications

Microglia/Macrophage Polarization Dynamics in White Matter after Traumatic Brain Injury

(2013) Guohua Wang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A quantitative spatiotemporal analysis of microglia morphology during ischemic stroke and reperfusion

(2013) Helena W Morrison et al.   Journal of Neuroinflammation

Metabolism of inflammation limited by AMPK and pseudo-starvation

(2013) Luke A. J. O'Neill et al.   NATURE

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

The Classification of Microglial Activation Phenotypes on Neurodegeneration and Regeneration in Alzheimer’s Disease Brain

(2012) Megan M. Varnum et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Molecular imaging of microglia/macrophages in the brain

(2012) Sriram Venneti et al.   GLIA

MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS

(2012) Eugene D. Ponomarev et al.   GLIA

Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states

(2012) Alok Kumar et al.   NEUROBIOLOGY OF AGING

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Imaging of microglia in patients with neurodegenerative disorders

(2012) Marios Politis   Frontiers in Pharmacology

Effects of Translocator Protein (18 kDa) Ligands on Microglial Activation and Neuronal Death in the Quinolinic-Acid-Injected Rat Striatum

(2011) Katherine R. Leaver et al.   ACS Chemical Neuroscience

Methylsalicylate 2-O-beta-D-lactoside, a novel salicylic acid analogue, acts as an anti-inflammatory agent on microglia and astrocytes

(2011) Xi Lan et al.   Journal of Neuroinflammation

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Translocator protein (18 kDa)/peripheral benzodiazepine receptor specific ligands induce microglia functions consistent with an activated state

(2010) Judy Choi et al.   GLIA

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

(2010) Rainer Rupprecht et al.   NATURE REVIEWS DRUG DISCOVERY

Microglial activation in stroke: Therapeutic targets

(2010) Midori A. Yenari et al.   Neurotherapeutics

Imaging of Microglia Activation in Stroke

(2010) Alexander Thiel et al.   STROKE

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Ro5-4864 promotes neonatal motor neuron survival and nerve regeneration in adult rats

(2008) Charles Mills et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Neuroprotective effect of Ro5-4864 following brain injury

(2008) Jean F. Soustiel et al.   EXPERIMENTAL NEUROLOGY