Forgetting as a form of adaptive engram cell plasticity

Engram cell connectivity: an evolving substrate for information storage

(2021) Tomás J Ryan et al.   CURRENT OPINION IN NEUROBIOLOGY

Failures of memory and the fate of forgotten memories

(2021) Ralph R. Miller   NEUROBIOLOGY OF LEARNING AND MEMORY

No consolidation without representation: Correspondence between neural and psychological representations in recent and remote memory

(2021) Asaf Gilboa et al.   NEURON

Microglia, synaptic dynamics and forgetting

(2021) Chao Wang et al.   BRAIN RESEARCH BULLETIN

Synaptic correlates of associative fear memory in the lateral amygdala

(2021) Dong Il Choi et al.   NEURON

Neurogenesis-dependent transformation of hippocampal engrams

(2021) Sangyoon Y. Ko et al.   NEUROSCIENCE LETTERS

Microglia, Lifestyle Stress, and Neurodegeneration

(2020) Charlotte Madore et al.   IMMUNITY

Assembly-Specific Disruption of Hippocampal Replay Leads to Selective Memory Deficit

(2020) Igor Gridchyn et al.   NEURON

Microglia mediate forgetting via complement-dependent synaptic elimination

(2020) Chao Wang et al.   SCIENCE

Memory engrams: Recalling the past and imagining the future

(2020) Sheena A. Josselyn et al.   SCIENCE

Early life experiences selectively mature learning and memory abilities

(2020) Benjamin Bessières et al.   Nature Communications

Functionally Distinct Neuronal Ensembles within the Memory Engram

(2020) Xiaochen Sun et al.   CELL

The memory toolbox: how genetic manipulations and cellular imaging are transforming our understanding of learned information

(2020) Antoine Harel et al.   Current Opinion in Behavioral Sciences

Memory trace interference impairs recall in a mouse model of Alzheimer’s disease

(2020) Stefanie Poll et al.   NATURE NEUROSCIENCE

Active Forgetting: Adaptation of Memory by Prefrontal Control

(2020) Michael C. Anderson et al.   Annual Review of Psychology

Accelerated long-term forgetting in healthy older adults predicts cognitive decline over 1 year

(2020) Alfie R. Wearn et al.   Alzheimers Research & Therapy

Sleep Promotes Downward Firing Rate Homeostasis

(2020) Alejandro Torrado Pacheco et al.   NEURON

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

(2019) Elena P. Moreno-Jiménez et al.   NATURE MEDICINE

Abolition of aberrant neurogenesis ameliorates cognitive impairment after stroke in mice

(2019) María Isabel Cuartero et al.   JOURNAL OF CLINICAL INVESTIGATION

A Hippocampus-Accumbens Tripartite Neuronal Motif Guides Appetitive Memory in Space

(2019) Stéphanie Trouche et al.   CELL

Distinct hippocampal engrams control extinction and relapse of fear memory

(2019) Anthony F. Lacagnina et al.   NATURE NEUROSCIENCE

Inhibition of Rac1-dependent forgetting alleviates memory deficits in animal models of Alzheimer’s disease

(2019) Wenjuan Wu et al.   Protein & Cell

Predictability Changes What We Remember in Familiar Temporal Contexts

(2019) Hyojeong Kim et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

The neurobiological foundation of memory retrieval

(2019) Paul W. Frankland et al.   NATURE NEUROSCIENCE

Neuromodulation in circuits of aversive emotional learning

(2019) Ekaterina Likhtik et al.   NATURE NEUROSCIENCE

Believing in dopamine

(2019) Samuel J. Gershman et al.   NATURE REVIEWS NEUROSCIENCE

Genetic dissection of active forgetting in labile and consolidated memories in Drosophila

(2019) Yang Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

REM sleep–active MCH neurons are involved in forgetting hippocampus-dependent memories

(2019) Shuntaro Izawa et al.   SCIENCE

A neural mechanism for deprivation state-specific expression of relevant memories in Drosophila

(2019) Bhagyashree Senapati et al.   NATURE NEUROSCIENCE

Forgetting at biologically realistic levels of neurogenesis in a large-scale hippocampal model

(2019) Lina M. Tran et al.   BEHAVIOURAL BRAIN RESEARCH

Content-based Dissociation of Hippocampal Involvement in Prediction

(2019) Peter Kok et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Human Adult Neurogenesis: Evidence and Remaining Questions

(2018) Gerd Kempermann et al.   Cell Stem Cell

Recovery of “Lost” Infant Memories in Mice

(2018) Axel Guskjolen et al.   CURRENT BIOLOGY

Associative prediction of visual shape in the hippocampus

(2018) Peter Kok et al.   JOURNAL OF NEUROSCIENCE

Elevation of Hippocampal Neurogenesis Induces a Temporally Graded Pattern of Forgetting of Contextual Fear Memories

(2018) Aijing Gao et al.   JOURNAL OF NEUROSCIENCE

Accelerated long-term forgetting in presymptomatic autosomal dominant Alzheimer's disease: a cross-sectional study

(2018) Philip S J Weston et al.   LANCET NEUROLOGY

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

(2018) Shawn F. Sorrells et al.   NATURE

Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization

(2018) Nannan Guo et al.   NATURE MEDICINE

Interregional synaptic maps among engram cells underlie memory formation

(2018) Jun-Hyeok Choi et al.   SCIENCE

Synapse-specific representation of the identity of overlapping memory engrams

(2018) Kareem Abdou et al.   SCIENCE

Reactivation of recall-induced neurons contributes to remote fear memory attenuation

(2018) Ossama Khalaf et al.   SCIENCE

Integration of Parallel Opposing Memories Underlies Memory Extinction

(2018) Johannes Felsenberg et al.   CELL

Engram Cell Excitability State Determines the Efficacy of Memory Retrieval

(2018) Michele Pignatelli et al.   NEURON

Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting

(2018) Ankit Awasthi et al.   SCIENCE

A retrieval-specific mechanism of adaptive forgetting in the mammalian brain

(2018) Pedro Bekinschtein et al.   Nature Communications

Dopamine Neurons Mediate Learning and Forgetting through Bidirectional Modulation of a Memory Trace

(2018) Jacob A. Berry et al.   Cell Reports

Social Isolation Induces Rac1-Dependent Forgetting of Social Memory

(2018) Yunlong Liu et al.   Cell Reports

Dopamine neurons drive fear extinction learning by signaling the omission of expected aversive outcomes

(2018) Ximena I Salinas-Hernández et al.   eLife

Everyday memory: towards a translationally effective method of modelling the encoding, forgetting and enhancement of memory

(2017) Mio Nonaka et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Optogenetic stimulation of dentate gyrus engrams restores memory in Alzheimer's disease mice

(2017) Jennifer N. Perusini et al.   HIPPOCAMPUS

Re-evaluation of learned information in Drosophila

(2017) Johannes Felsenberg et al.   NATURE

Modular organization of the brainstem noradrenaline system coordinates opposing learning states

(2017) Akira Uematsu et al.   NATURE NEUROSCIENCE

Dopamine reward prediction errors reflect hidden-state inference across time

(2017) Clara Kwon Starkweather et al.   NATURE NEUROSCIENCE

The Biology of Forgetting—A Perspective

(2017) Ronald L. Davis et al.   NEURON

The Persistence and Transience of Memory

(2017) Blake A. Richards et al.   NEURON

Environmental enrichment enhances cognitive flexibility in C57BL/6 mice on a touchscreen reversal learning task

(2017) Ariel Zeleznikow-Johnston et al.   NEUROPHARMACOLOGY

Ultrastructural evidence for synaptic scaling across the wake/sleep cycle

(2017) Luisa de Vivo et al.   SCIENCE

Homer1a drives homeostatic scaling-down of excitatory synapses during sleep

(2017) Graham H. Diering et al.   SCIENCE

From Engrams to Pathologies of the Brain

(2017) Christine A. Denny et al.   Frontiers in Neural Circuits

Hippocampal GABA enables inhibitory control over unwanted thoughts

(2017) Taylor W. Schmitz et al.   Nature Communications

Dopamine Receptor DAMB Signals via Gq to Mediate Forgetting in Drosophila

(2017) Sophie Himmelreich et al.   Cell Reports

Episodic Memory and Beyond: The Hippocampus and Neocortex in Transformation

(2016) Morris Moscovitch et al.   Annual Review of Psychology

Hippocampal Activation of Rac1 Regulates the Forgetting of Object Recognition Memory

(2016) Yunlong Liu et al.   CURRENT BIOLOGY

Computations underlying sensorimotor learning

(2016) Daniel M Wolpert et al.   CURRENT OPINION IN NEUROBIOLOGY

Memory Transformation Enhances Reinforcement Learning in Dynamic Environments

(2016) A. Santoro et al.   JOURNAL OF NEUROSCIENCE

Blocking Synaptic Removal of GluA2-Containing AMPA Receptors Prevents the Natural Forgetting of Long-Term Memories

(2016) P. V. Migues et al.   JOURNAL OF NEUROSCIENCE

Memory retrieval by activating engram cells in mouse models of early Alzheimer’s disease

(2016) Dheeraj S. Roy et al.   NATURE

A complement–microglial axis drives synapse loss during virus-induced memory impairment

(2016) Michael J. Vasek et al.   NATURE

Locus coeruleus and dopaminergic consolidation of everyday memory

(2016) Tomonori Takeuchi et al.   NATURE

PV plasticity sustained through D1/5 dopamine signaling required for long-term memory consolidation

(2016) Smitha Karunakaran et al.   NATURE NEUROSCIENCE

Computational principles of synaptic memory consolidation

(2016) Marcus K Benna et al.   NATURE NEUROSCIENCE

Infantile amnesia reflects a developmental critical period for hippocampal learning

(2016) Alessio Travaglia et al.   NATURE NEUROSCIENCE

The right time to learn: mechanisms and optimization of spaced learning

(2016) Paul Smolen et al.   NATURE REVIEWS NEUROSCIENCE

Unmasking Latent Inhibitory Connections in Human Cortex to Reveal Dormant Cortical Memories

(2016) H.C. Barron et al.   NEURON

Modulating Neuronal Competition Dynamics in the Dentate Gyrus to Rejuvenate Aging Memory Circuits

(2016) Kathleen M. McAvoy et al.   NEURON

Scribble Scaffolds a Signalosome for Active Forgetting

(2016) Isaac Cervantes-Sandoval et al.   NEURON

Hippocampal Somatostatin Interneurons Control the Size of Neuronal Memory Ensembles

(2016) Thomas Stefanelli et al.   NEURON

Inability to activate Rac1-dependent forgetting contributes to behavioral inflexibility in mutants of multiple autism-risk genes

(2016) Tao Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Cdc42-Dependent Forgetting Regulates Repetition Effect in Prolonging Memory Retention

(2016) Xuchen Zhang et al.   Cell Reports

Contrasting roles for parvalbumin-expressing inhibitory neurons in two forms of adult visual cortical plasticity

(2016) Eitan S Kaplan et al.   eLife

Hippocampal neurogenesis enhancers promote forgetting of remote fear memory after hippocampal reactivation by retrieval

(2016) Rie Ishikawa et al.   eLife

Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1

(2016) Robbert Havekes et al.   eLife

Forgetting of long-term memory requires activation of NMDA receptors, L-type voltage-dependent Ca2+ channels, and calcineurin

(2016) Ricardo Marcelo Sachser et al.   Scientific Reports

Updating memories—The role of prediction errors in memory reconsolidation

(2015) Marc T.J. Exton-McGuinness et al.   BEHAVIOURAL BRAIN RESEARCH

Sleep Facilitates Memory by Blocking Dopamine Neuron-Mediated Forgetting

(2015) Jacob A. Berry et al.   CELL

Memory engram storage and retrieval

(2015) Susumu Tonegawa et al.   CURRENT OPINION IN NEUROBIOLOGY

Memory Retrieval Requires Ongoing Protein Synthesis and NMDA Receptor Activity-Mediated AMPA Receptor Trafficking

(2015) J. Lopez et al.   JOURNAL OF NEUROSCIENCE

Inhibition of Rac1 Activity in the Hippocampus Impairs the Forgetting of Contextual Fear Memory

(2015) Lizhu Jiang et al.   MOLECULAR NEUROBIOLOGY

Activating positive memory engrams suppresses depression-like behaviour

(2015) Steve Ramirez et al.   NATURE

Labelling and optical erasure of synaptic memory traces in the motor cortex

(2015) Akiko Hayashi-Takagi et al.   NATURE

Visual recognition memory, manifested as long-term habituation, requires synaptic plasticity in V1

(2015) Sam F Cooke et al.   NATURE NEUROSCIENCE

Retrieval induces adaptive forgetting of competing memories via cortical pattern suppression

(2015) Maria Wimber et al.   NATURE NEUROSCIENCE

Finding the engram

(2015) Sheena A. Josselyn et al.   NATURE REVIEWS NEUROSCIENCE

Memory Engram Cells Have Come of Age

(2015) Susumu Tonegawa et al.   NEURON

Rehebbilitating Memory

(2015) Tomás J Ryan et al.   NEUROPSYCHOPHARMACOLOGY

Dissecting neural pathways for forgetting inDrosophilaolfactory aversive memory

(2015) Yichun Shuai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engram cells retain memory under retrograde amnesia

(2015) T. J. Ryan et al.   SCIENCE

Adult Hippocampal Neurogenesis in Natural Populations of Mammals

(2015) Irmgard Amrein   Cold Spring Harbor Perspectives in Biology

The Decay of Motor Memories Is Independent of Context Change Detection

(2015) Andrew E. Brennan et al.   PLoS Computational Biology

Replication and Analysis of Ebbinghaus’ Forgetting Curve

(2015) Jaap M. J. Murre et al.   PLoS One

The hippocampus, medial prefrontal cortex, and selective memory retrieval: Evidence from a rodent model of the retrieval-induced forgetting effect

(2014) Jade Q. Wu et al.   HIPPOCAMPUS

Long-term potentiation decay and memory loss are mediated by AMPAR endocytosis

(2014) Zhifang Dong et al.   JOURNAL OF CLINICAL INVESTIGATION

Engineering a memory with LTD and LTP

(2014) Sadegh Nabavi et al.   NATURE

Patterns across multiple memories are identified over time

(2014) Blake A Richards et al.   NATURE NEUROSCIENCE

Cortical Representations Are Reinstated by the Hippocampus during Memory Retrieval

(2014) Kazumasa Z. Tanaka et al.   NEURON

Network Plasticity in Adaptive Filtering and Behavioral Habituation

(2014) Mani Ramaswami   NEURON

Hippocampal Memory Traces Are Differentially Modulated by Experience, Time, and Adult Neurogenesis

(2014) Christine A. Denny et al.   NEURON

Pruning of memories by context-based prediction error

(2014) G. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Forgetting as a consequence of retrieval: A meta-analytic review of retrieval-induced forgetting.

(2014) Kou Murayama et al.   PSYCHOLOGICAL BULLETIN

Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy

(2014) K. G. Akers et al.   SCIENCE

A Normative Theory of Forgetting: Lessons from the Fruit Fly

(2014) Johanni Brea et al.   PLoS Computational Biology

Failure to observe renewal following retrieval-induced forgetting

(2013) Gonzalo Miguez et al.   BEHAVIOURAL PROCESSES

Dopaminergic Gene Polymorphisms Affect Long-term Forgetting in Old Age: Further Support for the Magnification Hypothesis

(2013) Goran Papenberg et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Decay of Motor Memories in the Absence of Error

(2013) P. A. Vaswani et al.   JOURNAL OF NEUROSCIENCE

Ventral Tegmental Dopamine Dysregulation Prevents Appetitive Memory Destabilization

(2013) A. C. Reichelt et al.   JOURNAL OF NEUROSCIENCE

Synapsin Function in GABA-ergic Interneurons Is Required for Short-Term Olfactory Habituation

(2013) M. K. Sadanandappa et al.   JOURNAL OF NEUROSCIENCE

Long-term dynamics of CA1 hippocampal place codes

(2013) Yaniv Ziv et al.   NATURE NEUROSCIENCE

The contextual brain: implications for fear conditioning, extinction and psychopathology

(2013) Stephen Maren et al.   NATURE REVIEWS NEUROSCIENCE

Dopamine and extinction: A convergence of theory with fear and reward circuitry

(2013) Antony D. Abraham et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Fear Extinction Causes Target-Specific Remodeling of Perisomatic Inhibitory Synapses

(2013) Stéphanie Trouche et al.   NEURON

GluA2-dependent AMPA receptor endocytosis and the decay of early and late long-term potentiation: possible mechanisms for forgetting of short- and long-term memories

(2013) O. Hardt et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Inception of a false memory by optogenetic manipulation of a hippocampal memory engram

(2013) X. Liu et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Prediction Error Governs Pharmacologically Induced Amnesia for Learned Fear

(2013) D. Sevenster et al.   SCIENCE

Creating a False Memory in the Hippocampus

(2013) S. Ramirez et al.   SCIENCE

Hippocampal neurogenesis and forgetting

(2013) Paul W. Frankland et al.   TRENDS IN NEUROSCIENCES

Regulation of AMPA receptor trafficking and synaptic plasticity

(2012) Victor Anggono et al.   CURRENT OPINION IN NEUROBIOLOGY

Plasticity of Recurrent Inhibition in the Drosophila Antennal Lobe

(2012) I. P. Sudhakaran et al.   JOURNAL OF NEUROSCIENCE

Overcoming Motor "Forgetting" Through Reinforcement Of Learned Actions

(2012) L. Shmuelof et al.   JOURNAL OF NEUROSCIENCE

Gustatory habituation in Drosophila relies on rutabaga (adenylate cyclase)-dependent plasticity of GABAergic inhibitory neurons

(2012) P. Paranjpe et al.   LEARNING & MEMORY

Ontogeny of contextual fear memory formation, specificity, and persistence in mice

(2012) K. G. Akers et al.   LEARNING & MEMORY

Optogenetic stimulation of a hippocampal engram activates fear memory recall

(2012) Xu Liu et al.   NATURE

Dopamine Is Required for Learning and Forgetting in Drosophila

(2012) Jacob A. Berry et al.   NEURON

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

The effect of adverse rearing environments on persistent memories in young rats: removing the brakes on infant fear memories

(2012) B L Callaghan et al.   Translational Psychiatry

Maternal separation results in early emergence of adult-like fear and extinction learning in infant rats.

(2011) Bridget L. Callaghan et al.   BEHAVIORAL NEUROSCIENCE

Learning-related feedforward inhibitory connectivity growth required for memory precision

(2011) Sarah Ruediger et al.   NATURE

Distinct molecular underpinnings of Drosophila olfactory trace conditioning

(2011) Y. Shuai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasticity of local GABAergic interneurons drives olfactory habituation

(2011) S. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Placing prediction into the fear circuit

(2011) Gavan P. McNally et al.   TRENDS IN NEUROSCIENCES

Forgetting Is Regulated through Rac Activity in Drosophila

(2010) Yichun Shuai et al.   CELL

The Hippocampus Plays a Selective Role in the Retrieval of Detailed Contextual Memories

(2010) Brian J. Wiltgen et al.   CURRENT BIOLOGY

Resistance to forgetting associated with hippocampus-mediated reactivation during new learning

(2010) Brice A Kuhl et al.   NATURE NEUROSCIENCE

Making memories last: the synaptic tagging and capture hypothesis

(2010) Roger L. Redondo et al.   NATURE REVIEWS NEUROSCIENCE

Relevance of synaptic tagging and capture to the persistence of long-term potentiation and everyday spatial memory

(2010) S.-H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium-Permeable AMPA Receptor Dynamics Mediate Fear Memory Erasure

(2010) R. L. Clem et al.   SCIENCE

Forgetting and small G protein Rac

(2010) Yichun Shuai et al.   Protein & Cell

Hippocampal-Neocortical Interactions in Memory Formation, Consolidation, and Reconsolidation

(2009) Szu-Han Wang et al.   Annual Review of Psychology

Adult Neurogenesis Modulates the Hippocampus-Dependent Period of Associative Fear Memory

(2009) Takashi Kitamura et al.   CELL

Changes in context-specificity during memory reconsolidation: Selective effects of hippocampal lesions

(2009) G. Winocur et al.   LEARNING & MEMORY

Preventing the return of fear in humans using reconsolidation update mechanisms

(2009) Daniela Schiller et al.   NATURE

Selective suppression of hippocampal ripples impairs spatial memory

(2009) Gabrielle Girardeau et al.   NATURE NEUROSCIENCE

Extinction-Reconsolidation Boundaries: Key to Persistent Attenuation of Fear Memories

(2009) M.-H. Monfils et al.   SCIENCE

Genetic control of active neural circuits

(2009) Leon Reijmers   Frontiers in Molecular Neuroscience

Neurons born in the adult dentate gyrus form functional synapses with target cells

(2008) Nicolas Toni et al.   NATURE NEUROSCIENCE

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY