Spatial and temporal localization of immune transcripts defines hallmarks and diversity in the tuberculosis granuloma

Regulatory T Cells Subvert Mycobacterial Containment in Patients Failing Extensively Drug-Resistant Tuberculosis Treatment

(2018) Malika Davids et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Network Visualization and Analysis of Spatially Aware Gene Expression Data with InsituNet

(2018) John Salamon et al.   Cell Systems

Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination

(2018) Sara B. Cohen et al.   Cell Host & Microbe

The promise of spatial transcriptomics for neuroscience in the era of molecular cell typing

(2017) Ed Lein et al.   SCIENCE

The Macrophage: A Disputed Fortress in the Battle against Mycobacterium tuberculosis

(2017) Christophe J. Queval et al.   Frontiers in Microbiology

Nitric Oxide in the Pathogenesis and Treatment of Tuberculosis

(2017) Hamidreza Jamaati et al.   Frontiers in Microbiology

DyNet: visualization and analysis of dynamic molecular interaction networks

(2016) Ivan H. Goenawan et al.   BIOINFORMATICS

Molecular basis of mycobacterial survival in macrophages

(2016) Jane Atesoh Awuh et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Syndecans promote mycobacterial internalization by lung epithelial cells

(2016) Natalie Zimmermann et al.   CELLULAR MICROBIOLOGY

Inflammatory signaling in human tuberculosis granulomas is spatially organized

(2016) Mohlopheni J Marakalala et al.   NATURE MEDICINE

Tuberculosis as a three-act play: A new paradigm for the pathogenesis of pulmonary tuberculosis

(2016) Robert L. Hunter   TUBERCULOSIS

Understanding Immune Cells in Tertiary Lymphoid Organ Development: It Is All Starting to Come Together

(2016) Gareth W. Jones et al.   Frontiers in Immunology

Lung necrosis and neutrophils reflect common pathways of susceptibility to Mycobacterium tuberculosis in genetically diverse, immune-competent mice

(2015) Muhammad K. K. Niazi et al.   Disease Models & Mechanisms

Mycobacterium tuberculosis infection of the ‘non-classical immune cell’

(2015) Philippa J Randall et al.   IMMUNOLOGY AND CELL BIOLOGY

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

(2015) Tauno Metsalu et al.   NUCLEIC ACIDS RESEARCH

Mouse models of human TB pathology: roles in the analysis of necrosis and the development of host-directed therapies

(2015) Igor Kramnik et al.   Seminars in Immunopathology

Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization

(2015) Hannah Priyadarshini Gideon et al.   PLoS Pathogens

Lipocalin 2-Dependent Inhibition of Mycobacterial Growth in Alveolar Epithelium

(2014) H. Saiga et al.   JOURNAL OF IMMUNOLOGY

CCR6-Dependent Positioning of Memory B Cells Is Essential for Their Ability To Mount a Recall Response to Antigen

(2014) Raul Elgueta et al.   JOURNAL OF IMMUNOLOGY

CD4+CD25highforkhead box protein 3+regulatory T lymphocytes suppress interferon-γ and CD107 expression in CD4+and CD8+T cells from tuberculous pleural effusions

(2013) L. Geffner et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Mycobacteria-Infected Dendritic Cells Attract Neutrophils That Produce IL-10 and Specifically Shut Down Th17 CD4 T Cells through Their IL-10 Receptor

(2013) E. Doz et al.   JOURNAL OF IMMUNOLOGY

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

(2013) Philana Ling Lin et al.   NATURE MEDICINE

In situ sequencing for RNA analysis in preserved tissue and cells

(2013) Rongqin Ke et al.   NATURE METHODS

Activated B Cells in the Granulomas of Nonhuman Primates Infected with Mycobacterium tuberculosis

(2012) Jia Yao Phuah et al.   AMERICAN JOURNAL OF PATHOLOGY

Evaluation of a Mouse Model of Necrotic Granuloma Formation Using C3HeB/FeJ Mice for Testing of Drugs against Mycobacterium tuberculosis

(2012) Emily R. Driver et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tertiary lymphoid organs in infection and autoimmunity

(2012) Katrijn Neyt et al.   TRENDS IN IMMUNOLOGY

IL-23 Is Required for Long-Term Control of Mycobacterium tuberculosis and B Cell Follicle Formation in the Infected Lung

(2011) Shabaana A. Khader et al.   JOURNAL OF IMMUNOLOGY

The development of inducible bronchus-associated lymphoid tissue depends on IL-17

(2011) Javier Rangel-Moreno et al.   NATURE IMMUNOLOGY

Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung

(2010) Paul S. Redford et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Limited Role for Lymphotoxin   in the Host Immune Response to Mycobacterium tuberculosis

(2010) N. Allie et al.   JOURNAL OF IMMUNOLOGY

In situ detection and genotyping of individual mRNA molecules

(2010) Chatarina Larsson et al.   NATURE METHODS

Dominant Role of the sst1 Locus in Pathogenesis of Necrotizing Lung Granulomas during Chronic Tuberculosis Infection and Reactivation in Genetically Resistant Hosts

(2009) Alexander V. Pichugin et al.   AMERICAN JOURNAL OF PATHOLOGY

Compartmentalization of Immune Responses in Human Tuberculosis

(2009) Sayma Rahman et al.   AMERICAN JOURNAL OF PATHOLOGY

Quantitative Comparison of Active and Latent Tuberculosis in the Cynomolgus Macaque Model

(2009) P. L. Lin et al.   INFECTION AND IMMUNITY

Early T-cell responses in tuberculosis immunity

(2008) Gary M. Winslow et al.   IMMUNOLOGICAL REVIEWS