The structure of neurofibromin isoform 2 reveals different functional states

Using antisense oligonucleotides for the physiological modulation of the alternative splicing of NF1 exon 23a during PC12 neuronal differentiation

(2021) Josep Biayna et al.   Scientific Reports

DeepEMhancer: a deep learning solution for cryo-EM volume post-processing

(2021) Ruben Sanchez-Garcia et al.   Communications Biology

Algorithmic Advances in Single Particle Cryo-EM Data Processing Using CryoSPARC

(2020) Ali Punjani   MICROSCOPY AND MICROANALYSIS

Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR

(2020) Wupeng Yan et al.   Cell Reports

Non-uniform refinement: adaptive regularization improves single-particle cryo-EM reconstruction

(2020) Ali Punjani et al.   NATURE METHODS

KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis

(2019) Dana Rabara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current Developments in Coot for Macromolecular Model Building of Electron Cryo‐microscopy and Crystallographic Data

(2019) Ana Casañal et al.   PROTEIN SCIENCE

JABAWS 2.2 distributed web services for Bioinformatics: protein disorder, conservation and RNA secondary structure

(2018) Peter V Troshin et al.   BIOINFORMATICS

cisTEM, user-friendly software for single-particle image processing

(2018) Timothy Grant et al.   eLife

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

Neurofibromatosis type 1 alternative splicing is a key regulator of Ras/ERK signaling and learning behaviors in mice

(2017) Hieu T. Nguyen et al.   HUMAN MOLECULAR GENETICS

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Neurofibromatosis type 1

(2017) David H. Gutmann et al.   Nature Reviews Disease Primers

The neurofibromin recruitment factor Spred1 binds to the GAP related domain without affecting Ras inactivation

(2016) Theresia Dunzendorfer-Matt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PDBe: improved accessibility of macromolecular structure data from PDB and EMDB

(2015) Sameer Velankar et al.   NUCLEIC ACIDS RESEARCH

GTP-Dependent K-Ras Dimerization

(2015) Serena Muratcioglu et al.   STRUCTURE

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

A shared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1

(2012) I. B. Stowe et al.   GENES & DEVELOPMENT

Alternative splicing of the neurofibromatosis type I pre-mRNA

(2011) Victoria A. Barron et al.   BIOSCIENCE REPORTS

MultiBac: expanding the research toolbox for multiprotein complexes

(2011) Christoph Bieniossek et al.   TRENDS IN BIOCHEMICAL SCIENCES

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Birth incidence and prevalence of tumor-prone syndromes: Estimates from a UK family genetic register service

(2010) D.G. Evans et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Structural and biochemical consequences of NF1 associated nontruncating mutations in the Sec14-PH module of neurofibromin

(2010) Stefan Welti et al.   HUMAN MUTATION

Cytosolic zinc buffering and muffling: Their role in intracellular zinc homeostasis

(2010) Robert A. Colvin et al.   Metallomics

Developmental Abnormalities and Cancer Predisposition in Neurofibromatosis Type 1

(2009) Lidia Larizza et al.   CURRENT MOLECULAR MEDICINE

How does multiple testing correction work?

(2009) William S Noble   NATURE BIOTECHNOLOGY

Fast and accurate automatic structure prediction with HHpred

(2009) Andrea Hildebrand et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS