Engineered platelets: Advocates for tumor immunotherapy

Antibody Engineered Platelets Attracted by Bacteria‐Induced Tumor‐Specific Blood Coagulation for Checkpoint Inhibitor Immunotherapy

(2021) Jin‐Xuan Fan et al.   ADVANCED FUNCTIONAL MATERIALS

PLGA-particle vaccine carrying TLR3/RIG-I ligand Riboxxim synergizes with immune checkpoint blockade for effective anti-cancer immunotherapy

(2021) Julia Koerner et al.   Nature Communications

Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis

(2021) Hongjun Li et al.   Nature Communications

Near-infrared light–triggered platelet arsenal for combined photothermal-immunotherapy against cancer

(2021) Yanlin Lv et al.   Science Advances

‘Off-the-shelf’ allogeneic CAR T cells: development and challenges

(2020) S. Depil et al.   NATURE REVIEWS DRUG DISCOVERY

Therapeutic strategies for thrombosis: new targets and approaches

(2020) Nigel Mackman et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting pulmonary tumor microenvironment with CXCR4-inhibiting nanocomplex to enhance anti–PD-L1 immunotherapy

(2020) Zhaoting Li et al.   Science Advances

Platelet-Leukocyte Interplay in Cancer Development and Progression

(2020) Dagmar Stoiber et al.   Cells

Improving Cancer Immunotherapy by Cell Membrane‐Camouflaged Nanoparticles

(2020) Ziling Zeng et al.   ADVANCED FUNCTIONAL MATERIALS

A decade of immune-checkpoint inhibitors in cancer therapy

(2020) Caroline Robert   Nature Communications

CAR T cell therapies for patients with multiple myeloma

(2020) Lekha Mikkilineni et al.   Nature Reviews Clinical Oncology

Hemostasis vs. homeostasis: Platelets are essential for preserving vascular barrier function in the absence of injury or inflammation

(2020) Shuchi Gupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelets: emerging facilitators of cellular crosstalk in rheumatoid arthritis

(2019) Oore-ofe Olumuyiwa-Akeredolu et al.   Nature Reviews Rheumatology

Antibody-Armed Platelets for the Regenerative Targeting of Endogenous Stem Cells

(2019) Deliang Shen et al.   NANO LETTERS

Immuno-oncology drug development goes global

(2019) Jia Xin Yu et al.   NATURE REVIEWS DRUG DISCOVERY

The Era of Thromboinflammation: Platelets Are Dynamic Sensors and Effector Cells During Infectious Diseases

(2019) Li Guo et al.   Frontiers in Immunology

Recent advances in nanosized drug delivery systems for overcoming the barriers to anti-PD immunotherapy of cancer

(2019) Xiaochen Liu et al.   Nano Today

Leveraging Engineering of Cells for Drug Delivery

(2018) Zhaowei Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production

(2018) Yukitaka Ito et al.   CELL

An overview on Vadimezan (DMXAA): The vascular disrupting agent

(2018) Amir Daei Farshchi Adli et al.   Chemical Biology & Drug Design

Circulating Platelets as Mediators of Immunity, Inflammation, and Thrombosis

(2018) Milka Koupenova et al.   CIRCULATION RESEARCH

Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer

(2018) Nikolaos Zacharakis et al.   NATURE MEDICINE

The role of platelets in acute kidney injury

(2018) Marcel P. B. Jansen et al.   Nature Reviews Nephrology

The non-haemostatic role of platelets in systemic lupus erythematosus

(2018) Petrus Linge et al.   Nature Reviews Rheumatology

Cancer immunotherapy using checkpoint blockade

(2018) Antoni Ribas et al.   SCIENCE

Platelet Storage Lesions: What More Do We Know Now?

(2018) Monica Suet Ying Ng et al.   TRANSFUSION MEDICINE REVIEWS

Programming CAR-T cells to kill cancer

(2018) Louai Labanieh et al.   Nature Biomedical Engineering

Targeted repair of heart injury by stem cells fused with platelet nanovesicles

(2018) Junnan Tang et al.   Nature Biomedical Engineering

Quantifying Platelet Margination in Diabetic Blood Flow

(2018) Hung-Yu Chang et al.   BIOPHYSICAL JOURNAL

Engineering PD-1-Presenting Platelets for Cancer Immunotherapy

(2018) Xudong Zhang et al.   NANO LETTERS

In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment

(2018) Qian Chen et al.   Nature Nanotechnology

Platelet biology and functions: new concepts and clinical perspectives

(2018) Paola E. J. van der Meijden et al.   Nature Reviews Cardiology

Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy

(2018) Quanyin Hu et al.   Nature Biomedical Engineering

Platelet for drug delivery

(2018) Yifei Lu et al.   CURRENT OPINION IN BIOTECHNOLOGY

Platelet microvesicles in health and disease

(2017) Imene Melki et al.   PLATELETS

Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα

(2017) Yunmei Wang et al.   Nature Communications

In situ activation of platelets with checkpoint inhibitors for post-surgical cancer immunotherapy

(2017) Chao Wang et al.   Nature Biomedical Engineering

Cell-Derived Microparticles in Patients with Type 2 Diabetes Mellitus: a Systematic Review and Meta-Analysis

(2016) Sheyu Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A cooperative polymeric platform for tumor-targeted drug delivery

(2016) Wantong Song et al.   Chemical Science

Platelet transfusions in platelet consumptive disorders are associated with arterial thrombosis and in-hospital mortality

(2015) R. Goel et al.   BLOOD

Single platelets seal neutrophil-induced vascular breaches via GPVI during immune-complex-mediated inflammation in mice

(2015) A. Gros et al.   BLOOD

Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

(2015) Suzanne L. Topalian et al.   CANCER CELL

The role of platelets in the recruitment of leukocytes during vascular disease

(2015) G. Ed Rainger et al.   PLATELETS

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

Emerging roles for platelets as immune and inflammatory cells

(2014) C. N. Morrell et al.   BLOOD

Platelets: at the nexus of antimicrobial defence

(2014) Michael R. Yeaman   NATURE REVIEWS MICROBIOLOGY

The causal role of megakaryocyte–platelet hyperactivity in acute coronary syndromes

(2012) John F. Martin et al.   Nature Reviews Cardiology

Shear-Activated Nanotherapeutics for Drug Targeting to Obstructed Blood Vessels

(2012) N. Korin et al.   SCIENCE

Hemorrhage caused by antiangiogenic therapy within previously irradiated areas: expected consequence of tumor shrinkage or a warning for antiangiogenic agents combined to radiotherapy?

(2011) J.- C. Soria et al.   ANNALS OF ONCOLOGY

The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A

(2011) M. J. Flick et al.   BLOOD

Increased Efficacy of Breast Cancer Chemotherapy in Thrombocytopenic Mice

(2011) M. Demers et al.   CANCER RESEARCH

Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum

(2011) Adriana Vieira-de-Abreu et al.   Seminars in Immunopathology

Response to letter from B.A. Badlou regarding H. Ohto and K.E. Nollet article entitled “Overview on platelet preservation: Better controls over storage lesion” Transfusion and Apheresis Science 44 (2011) 321–325

(2011) Hitoshi Ohto et al.   TRANSFUSION AND APHERESIS SCIENCE

Platelet CD40L at the interface of adaptive immunity

(2010) Bennett D. Elzey et al.   THROMBOSIS RESEARCH