A cooperative polymeric platform for tumor-targeted drug delivery

Aptamer Nanomedicine for Cancer Therapeutics: Barriers and Potential for Translation

(2015) Yeh-Hsing Lao et al.   ACS Nano

Cisplatin-loaded polymeric nanoparticles: Characterization and potential exploitation for the treatment of non-small cell lung carcinoma

(2015) Chunshan Shi et al.   Acta Biomaterialia

Pharmacokinetics, biodistribution and in vivo efficacy of cisplatin loaded poly(l-glutamic acid)-g-methoxy poly(ethylene glycol) complex nanoparticles for tumor therapy

(2015) Haiyang Yu et al.   JOURNAL OF CONTROLLED RELEASE

Coadministration of Vascular Disrupting Agents and Nanomedicines to Eradicate Tumors from Peripheral and Central Regions

(2015) Wantong Song et al.   Small

Bioorthogonal oxime ligation mediated in vivo cancer targeting

(2015) Li Tang et al.   Chemical Science

Comprehensive studies of pharmacokinetics and biodistribution of indocyanine green and liposomal indocyanine green by multispectral optoacoustic tomography

(2015) Wantong Song et al.   RSC Advances

Chemical Tumor-Targeting of Nanoparticles Based on Metabolic Glycoengineering and Click Chemistry

(2014) Sangmin Lee et al.   ACS Nano

Tumor Vasculature Targeted Photodynamic Therapy for Enhanced Delivery of Nanoparticles

(2014) Zipeng Zhen et al.   ACS Nano

Bimodal Tumor-Targeting from Microenvironment Responsive Hyaluronan Layer-by-Layer (LbL) Nanoparticles

(2014) Erik C. Dreaden et al.   ACS Nano

Anti-tumor efficacy of c(RGDfK)-decorated polypeptide-based micelles co-loaded with docetaxel and cisplatin

(2014) Wantong Song et al.   BIOMATERIALS

EPR: Evidence and fallacy

(2014) Joseph W. Nichols et al.   JOURNAL OF CONTROLLED RELEASE

Glycosylation-mediated targeting of carriers

(2014) Shigeru Kawakami et al.   JOURNAL OF CONTROLLED RELEASE

Progress of drug-loaded polymeric micelles into clinical studies

(2014) Horacio Cabral et al.   JOURNAL OF CONTROLLED RELEASE

Automated Modular Synthesis of Aptamer–Drug Conjugates for Targeted Drug Delivery

(2014) RuoWen Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Passive versus Active Tumor Targeting Using RGD- and NGR-Modified Polymeric Nanomedicines

(2014) Sijumon Kunjachan et al.   NANO LETTERS

Drug-induced amplification of nanoparticle targeting to tumors

(2014) Kevin Y. Lin et al.   Nano Today

Quantitative profiling of the protein coronas that form around nanoparticles

(2014) Dominic Docter et al.   Nature Protocols

Polythiazole linkers as functional rigid connectors: a new RGD cyclopeptide with enhanced integrin selectivity

(2014) J. Ruiz-Rodríguez et al.   Chemical Science

Lactose targeting oxaliplatin prodrug loaded micelles for more effective chemotherapy of hepatocellular carcinoma

(2014) Lixin Yang et al.   Journal of Materials Chemistry B

Toward the Next-Generation Nanomedicines: Design of Multifunctional Multiblock Polyurethanes for Effective Cancer Treatment

(2013) Mingming Ding et al.   ACS Nano

In Vivo Tumor Targeting and Image-Guided Drug Delivery with Antibody-Conjugated, Radiolabeled Mesoporous Silica Nanoparticles

(2013) Feng Chen et al.   ACS Nano

Microfluidic Platform for Combinatorial Synthesis and Optimization of Targeted Nanoparticles for Cancer Therapy

(2013) Pedro M. Valencia et al.   ACS Nano

Differential Anticancer Drug Delivery with a Nanogel Sensitive to Bacteria-Accumulated Tumor Artificial Environment

(2013) Meng-Hua Xiong et al.   ACS Nano

Aptamer-conjugated and doxorubicin-loaded unimolecular micelles for targeted therapy of prostate cancer

(2013) Wenjin Xu et al.   BIOMATERIALS

Phase I Safety, Pharmacokinetic and Pharmacodynamic Evaluation of the Vascular Disrupting Agent Ombrabulin (AVE8062) in Patients with Advanced Solid Tumors

(2013) C. Sessa et al.   CLINICAL CANCER RESEARCH

Synergistic targeting/prodrug strategies for intravesical drug delivery — Lectin-modified PLGA microparticles enhance cytotoxicity of stearoyl gemcitabine by contact-dependent transfer

(2013) L. Neutsch et al.   JOURNAL OF CONTROLLED RELEASE

Folate-Based Near-Infrared Fluorescent Theranostic Gemcitabine Delivery

(2013) Zhigang Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A phase II clinical trial of the Vascular Disrupting Agent BNC105P as second line chemotherapy for advanced Malignant Pleural Mesothelioma

(2013) Anna K. Nowak et al.   LUNG CANCER

Nanoparticle Delivered Vascular Disrupting Agents (VDAs): Use of TNF-Alpha Conjugated Gold Nanoparticles for Multimodal Cancer Therapy

(2013) Mithun M. Shenoi et al.   MOLECULAR PHARMACEUTICS

High-resolution, serial intravital microscopic imaging of nanoparticle delivery and targeting in a small animal tumor model

(2013) Bryan Ronain Smith et al.   Nano Today

Tumour heterogeneity in the clinic

(2013) Philippe L. Bedard et al.   NATURE

Influence of tumour micro-environment heterogeneity on therapeutic response

(2013) Melissa R. Junttila et al.   NATURE

Strategies for advancing cancer nanomedicine

(2013) Vikash P. Chauhan et al.   NATURE MATERIALS

Cooperative Dual-Activity Targeted Nanomedicine for Specific and Effective Prostate Cancer Therapy

(2012) Hung-Wei Yang et al.   ACS Nano

Markedly Enhanced Permeability and Retention Effects Induced by Photo-immunotherapy of Tumors

(2012) Kohei Sano et al.   ACS Nano

Carboplatin and Paclitaxel Plus ASA404 as First-Line Chemotherapy for Extensive-Stage Small-Cell Lung Cancer: A Multicenter Single Arm Phase II Trial (SAKK 15/08)

(2012) Martin Früh et al.   Clinical Lung Cancer

Phase I, pharmacokinetic and pharmacodynamic evaluation of CYT997, an orally-bioavailable cytotoxic and vascular-disrupting agent

(2012) Matthew Burge et al.   INVESTIGATIONAL NEW DRUGS

Folic Acid-Modified Mesoporous Silica Nanoparticles for Cellular and Nuclear Targeted Drug Delivery

(2012) Fabiola Porta et al.   Advanced Healthcare Materials

Design of Multifunctional Micelle for Tumor-Targeted Intracellular Drug Release and Fluorescent Imaging

(2011) Weiwei Wang et al.   ADVANCED MATERIALS

Targeted drug delivery to tumors: Myths, reality and possibility

(2011) You Han Bae et al.   JOURNAL OF CONTROLLED RELEASE

Nanomedicine(s) under the Microscope

(2011) Ruth Duncan et al.   MOLECULAR PHARMACEUTICS

Nanoparticles that communicate in vivo to amplify tumour targeting

(2011) Geoffrey von Maltzahn et al.   NATURE MATERIALS

The development of the tumor vascular-disrupting agent ASA404 (vadimezan, DMXAA): current status and future opportunities

(2010) Michelle Head et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

ASA404: a tumor vascular-disrupting agent with broad potential for cancer therapy

(2010) Bruce C Baguley et al.   Future Oncology

Targeting of drugs and nanoparticles to tumors

(2010) Erkki Ruoslahti et al.   JOURNAL OF CELL BIOLOGY

Biodegradable calcium phosphate nanoparticle with lipid coating for systemic siRNA delivery

(2009) Jun Li et al.   JOURNAL OF CONTROLLED RELEASE

Anticancer strategies involving the vasculature

(2009) Victoria L. Heath et al.   Nature Reviews Clinical Oncology

Review article: Coagulation cascade and therapeutics update: Relevance to nephrology. Part 1: Overview of coagulation, thrombophilias and history of anticoagulants

(2009) REBECCA L C ADAMS et al.   NEPHROLOGY

Drug targeting and tumor heterogeneity

(2008) You Han Bae   JOURNAL OF CONTROLLED RELEASE

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles

(2008) S. Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA