Complement multiplex testing: Concept, promises and pitfalls

Updates on liquid biopsy: current trends and future perspectives for clinical application in solid tumors

(2021) Pamela Pinzani et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

European Society for Immunodeficiencies (ESID) and European Reference Network on Rare Primary Immunodeficiency, Autoinflammatory and Autoimmune Diseases (ERN RITA) Complement Guideline: Deficiencies, Diagnosis, and Management

(2020) Nicholas Brodszki et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Complement profile in microscopic polyangiitis and granulomatosis with polyangiitis: analysis using sera from a nationwide prospective cohort study

(2020) S Fukui et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Newborn Screening for Presymptomatic Diagnosis of Complement and Phagocyte Deficiencies

(2020) Mahya Dezfouli et al.   Frontiers in Immunology

Proteomic Analysis of Complement Proteins in Membranous Nephropathy

(2020) Aishwarya Ravindran et al.   Kidney International Reports

Complement protein levels and MBL2 polymorphisms are associated with dengue and disease severity

(2020) Ngo Truong Giang et al.   Scientific Reports

Animal-Free Human Whole Blood Sepsis Model to Study Changes in Innate Immunity

(2020) David Alexander Christian Messerer et al.   Frontiers in Immunology

A robust multiplexed assay to quantify C1-inhibitor, C1q, and C4 proteins for in vitro diagnosis of hereditary angioedema from dried blood spot

(2020) Yongquan Lai et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Erratum. Urine Complement Proteins and the Risk of Kidney Disease Progression and Mortality in Type 2 Diabetes. Diabetes Care 2018;41:2361–2369

(2019) Tomas Vaisar et al.   DIABETES CARE

LC-MS bioanalysis of intact proteins and peptides

(2019) Lijuan Kang et al.   BIOMEDICAL CHROMATOGRAPHY

Complement and its environmental determinants in the progression of human rheumatoid arthritis

(2019) Elizabeth A. Bemis et al.   MOLECULAR IMMUNOLOGY

Discrepancies in plasma levels of complement components measured by a newly introduced commercially available magnetic bead technique compared to presently available clinical reference intervals

(2019) Kerstin Sandholm et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Complement activation products in the circulation and urine of primary membranous nephropathy

(2019) Mu-fan Zhang et al.   BMC Nephrology

Analysis of the Complement System in the Clinical Immunology Laboratory

(2019) Morris Ling et al.   CLINICS IN LABORATORY MEDICINE

Critical considerations for immunocapture enrichment LC–MS bioanalysis of protein therapeutics and biomarkers

(2018) Yue Zhao et al.   Bioanalysis

Progress in high-sensitivity hybrid LC–MS/MS methods for the bioanalysis of protein drugs and performance tests for their validation

(2018) Jeffrey X Duggan   Bioanalysis

Interpretation of Serological Complement Biomarkers in Disease

(2018) Kristina N. Ekdahl et al.   Frontiers in Immunology

Newborn Screening for Primary Immunodeficiency Diseases: History, Current and Future Practice

(2017) Jovanka R. King et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Kallikrein Cleaves C3 and Activates Complement

(2017) Sarah Irmscher et al.   Journal of Innate Immunity

Standardization approaches in absolute quantitative proteomics with mass spectrometry

(2017) Francisco Calderón-Celis et al.   MASS SPECTROMETRY REVIEWS

Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation

(2016) Kristina N. Ekdahl et al.   IMMUNOLOGICAL REVIEWS

A whole-molecule immunocapture LC–MS approach for the in vivo quantitation of biotherapeutics

(2016) John F Kellie et al.   Bioanalysis

ELISA in the multiplex era: Potentials and pitfalls

(2015) Patrick J. Tighe et al.   Proteomics Clinical Applications

Defining the Complement Biomarker Profile of C3 Glomerulopathy

(2014) Y. Zhang et al.   Clinical Journal of the American Society of Nephrology

Analytical Validation Considerations of Multiplex Mass-Spectrometry-Based Proteomic Platforms for Measuring Protein Biomarkers

(2014) Emily S. Boja et al.   JOURNAL OF PROTEOME RESEARCH

Are complement deficiencies really rare? Overview on prevalence, clinical importance and modern diagnostic approach

(2014) Anete Sevciovic Grumach et al.   MOLECULAR IMMUNOLOGY

A Novel In vitro Model for Studying the Interactions Between Human Whole Blood and Endothelium

(2014) Sofia Nordling et al.   Jove-Journal of Visualized Experiments

Utility, reliability and reproducibility of immunoassay multiplex kits

(2013) Paddy Tighe et al.   METHODS

Thrombin generates previously unidentified C5 products that support the terminal complement activation pathway

(2012) M. J. Krisinger et al.   BLOOD

Complement Activation Contributes to the Injury and Outcome of Kidney in Human Anti-glomerular Basement Membrane Disease

(2012) Rui Ma et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Validation of immunoassay for protein biomarkers: Bioanalytical study plan implementation to support pre-clinical and clinical studies

(2011) Marie-Anne Valentin et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Hereditary angiodema: a current state-of-the-art review, VII: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema

(2010) Tom Bowen et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Molecular Intercommunication between the Complement and Coagulation Systems

(2010) U. Amara et al.   JOURNAL OF IMMUNOLOGY

Measurement and Quality Control Issues in Multiplex Protein Assays: A Case Study

(2009) A. A. Ellington et al.   CLINICAL CHEMISTRY

Validation of Analytic Methods for Biomarkers Used in Drug Development

(2008) C. H. Chau et al.   CLINICAL CANCER RESEARCH