Oncogene-dependent sloppiness in mRNA translation

Adaptive RSK‐EphA2‐GPRC5A signaling switch triggers chemotherapy resistance in ovarian cancer

(2020) Lidia Moyano‐Galceran et al.   EMBO Molecular Medicine

mTOR at the nexus of nutrition, growth, ageing and disease

(2020) Grace Y. Liu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis

(2020) Richard Y. Ebright et al.   SCIENCE

Ribosome Collisions Trigger General Stress Responses to Regulate Cell Fate

(2020) Colin Chih-Chien Wu et al.   CELL

Regulators of Viral Frameshifting: More Than RNA Influences Translation Events

(2020) Wesley D. Penn et al.   Annual Review of Virology

Ribosomal stress-surveillance: three pathways is a magic number

(2020) Anna Constance Vind et al.   NUCLEIC ACIDS RESEARCH

Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes

(2020) Maxim V. Gerashchenko et al.   Scientific Reports

Anti-tumour immunity induces aberrant peptide presentation in melanoma

(2020) Osnat Bartok et al.   NATURE

Regulation of HIV-1 Gag-Pol Expression by Shiftless, an Inhibitor of Programmed -1 Ribosomal Frameshifting

(2019) Xinlu Wang et al.   CELL

Targeting mTOR for cancer therapy

(2019) Hui Hua et al.   Journal of Hematology & Oncology

Ribosome collisions alter frameshifting at translational reprogramming motifs in bacterial mRNAs

(2019) Angela M. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential

(2018) Liqin Wang et al.   CELL

Reversal of indoleamine 2,3-dioxygenase–mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme

(2018) Todd A Triplett et al.   NATURE BIOTECHNOLOGY

Translation Elongation and Recoding in Eukaryotes

(2018) Thomas E. Dever et al.   Cold Spring Harbor Perspectives in Biology

Codon-specific translation reprogramming promotes resistance to targeted therapy

(2018) Francesca Rapino et al.   NATURE

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Programmed Ribosomal Frameshifting Generates a Copper Transporter and a Copper Chaperone from the Same Gene

(2017) Sezen Meydan et al.   MOLECULAR CELL

Human melanoma cells resistant to MAPK inhibitors can be effectively targeted by inhibition of the p90 ribosomal S6 kinase

(2017) Corinna Kosnopfel et al.   Oncotarget

Molecular Pathways: The eIF4F Translation Initiation Complex—New Opportunities for Cancer Treatment

(2016) Hélène Malka-Mahieu et al.   CLINICAL CANCER RESEARCH

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

(2016) Stefka Tyanova et al.   Nature Protocols

Ribosome-associated protein quality control

(2016) Onn Brandman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ribosome-associated protein quality control

(2016) Onn Brandman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation

(2016) Ryuta Ishimura et al.   eLife

Targeting the eIF4F Translation Initiation Complex: A Critical Nexus for Cancer Development

(2015) J. Pelletier et al.   CANCER RESEARCH

Ribosome Excursions during mRNA Translocation Mediate Broad Branching of Frameshift Pathways

(2015) Shannon Yan et al.   CELL

Differential Requirements for eIF4E Dose in Normal Development and Cancer

(2015) Morgan L. Truitt et al.   CELL

Non-genomic and Immune Evolution of Melanoma Acquiring MAPKi Resistance

(2015) Willy Hugo et al.   CELL

Hyperphosphorylation of ribosomal protein S6 predicts unfavorable clinical survival in non-small cell lung cancer

(2015) Bojiang Chen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

(2015) Luping Lin et al.   NATURE GENETICS

Targeting the translation machinery in cancer

(2015) Mamatha Bhat et al.   NATURE REVIEWS DRUG DISCOVERY

The immunoproteasome and viral infection: a complex regulator of inflammation

(2015) Mary K. McCarthy et al.   Frontiers in Microbiology

Phosphorylation of Ribosomal Protein S6 Attenuates DNA Damage and Tumor Suppression during Development of Pancreatic Cancer

(2013) A. Khalaileh et al.   CANCER RESEARCH

MAP Kinase Pathway Alterations in BRAF-Mutant Melanoma Patients with Acquired Resistance to Combined RAF/MEK Inhibition

(2013) N. Wagle et al.   Cancer Discovery

The translational landscape of mTOR signalling steers cancer initiation and metastasis

(2012) Andrew C. Hsieh et al.   NATURE

Efficient -2 frameshifting by mammalian ribosomes to synthesize an additional arterivirus protein

(2012) Y. Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms and implications of programmed translational frameshifting

(2012) Jonathan D. Dinman   Wiley Interdisciplinary Reviews-RNA

On programmed ribosomal frameshifting: the alternative proteomes

(2012) Robin Ketteler   Frontiers in Genetics

Programmed ribosomal frameshifting in the expression of the regulator of intestinal stem cell proliferation, adenomatous polyposis coli (APC)

(2011) Pavel V. Baranov et al.   RNA Biology

Genetic Dissection of the Oncogenic mTOR Pathway Reveals Druggable Addiction to Translational Control via 4EBP-eIF4E

(2010) Andrew C. Hsieh et al.   CANCER CELL

An Evolutionarily Conserved Mechanism for Controlling the Efficiency of Protein Translation

(2010) Tamir Tuller et al.   CELL

The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation

(2010) Jiangbin Ye et al.   EMBO JOURNAL

Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus

(2010) Federica Di Nicolantonio et al.   JOURNAL OF CLINICAL INVESTIGATION

CD8+T cell concentration determines their efficiency in killing cognate antigen–expressing syngeneic mammalian cells in vitro and in mouse tissues

(2010) Sadna Budhu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting p70S6K Prevented Lung Metastasis in a Breast Cancer Xenograft Model

(2010) U. Akar et al.   MOLECULAR CANCER THERAPEUTICS

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency

(2008) Maria Barna et al.   NATURE