Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice

Neuroinvasion of SARS-CoV-2 in human and mouse brain

(2021) Eric Song et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuropathology associated with SARS-CoV-2 infection

(2021) Markus Glatzel et al.   LANCET

SARS-CoV-2 Infection in the Central and Peripheral Nervous System-Associated Morbidities and Their Potential Mechanism

(2021) Mohan Kumar Muthu Karuppan et al.   MOLECULAR NEUROBIOLOGY

Observational cohort study of IP-10’s potential as a biomarker to aid in inflammation regulation within a clinical decision support protocol for patients with severe COVID-19

(2021) Shaul Lev et al.   PLoS One

Neuroinvasion and Encephalitis Following Intranasal Inoculation of SARS-CoV-2 in K18-hACE2 Mice

(2021) Pratima Kumari et al.   Viruses-Basel

COVID-19 neuropathology at Columbia University Irving Medical Center/New York Presbyterian Hospital

(2021) Kiran T Thakur et al.   BRAIN

Innate immune and inflammatory responses to SARS-CoV-2: implications for COVID-19

(2021) Shea A. Lowery et al.   Cell Host & Microbe

Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions

(2021) Marius Schwabenland et al.   IMMUNITY

Neurological manifestations of COVID-19: A comprehensive literature review and discussion of mechanisms

(2021) Anton Johansson et al.   JOURNAL OF NEUROIMMUNOLOGY

Dysregulation of brain and choroid plexus cell types in severe COVID-19

(2021) Andrew C. Yang et al.   NATURE

Unbiased Analysis of Temporal Changes in Immune Serum Markers in Acute COVID-19 Infection With Emphasis on Organ Failure, Anti-Viral Treatment, and Demographic Characteristics

(2021) Krzysztof Laudanski et al.   Frontiers in Immunology

Complement Anaphylatoxins and Inflammatory Cytokines as Prognostic Markers for COVID-19 Severity and In-Hospital Mortality

(2021) Bandar Alosaimi et al.   Frontiers in Immunology

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation

(2020) Charlene Smith-Geater et al.   Stem Cell Reports

Neuropathology of COVID-19: a spectrum of vascular and acute disseminated encephalomyelitis (ADEM)-like pathology

(2020) R. Ross Reichard et al.   ACTA NEUROPATHOLOGICA

Pathogenesis of SARS-CoV-2 in transgenic mice expressing human angiotensin-converting enzyme 2

(2020) Ren-Di Jiang et al.   CELL

A Mouse Model of SARS-CoV-2 Infection and Pathogenesis

(2020) Shi-Hui Sun et al.   Cell Host & Microbe

Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system

(2020) Vrushali Mangale et al.   GLIA

The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice

(2020) Linlin Bao et al.   NATURE

Differential regulation of TREM2 and CSF1R in CNS macrophages in an SIV/macaque model of HIV CNS disease

(2020) Audrey C. Knight et al.   JOURNAL OF NEUROVIROLOGY

Acute necrotizing encephalopathy with SARS-CoV-2 RNA confirmed in cerebrospinal fluid

(2020) Johan Virhammar et al.   NEUROLOGY

Effects of IL-34 on Macrophage Immunological Profile in Response to Alzheimer's-Related Aβ42 Assemblies

(2020) Leah R. Zuroff et al.   Frontiers in Immunology

SARS-CoV-2 infects the brain choroid plexus and disrupts the blood-CSF-barrier in human brain organoids

(2020) Laura Pellegrini et al.   Cell Stem Cell

Single-cell RNA sequencing reveals the diversity of the immunological landscape following CNS infection by a murine coronavirus

(2020) Amber R. Syage et al.   JOURNAL OF VIROLOGY

Animal models for COVID-19

(2020) César Muñoz-Fontela et al.   NATURE

Publisher Correction: SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function

(2020) Emma S. Winkler et al.   NATURE IMMUNOLOGY

Microglia depletion exacerbates demyelination and impairs remyelination in a neurotropic coronavirus infection

(2020) Alan Sariol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CSF1R signaling is a regulator of pathogenesis in progressive MS

(2020) Nellwyn Hagan et al.   Cell Death & Disease

Neuronophagia and microglial nodules in a SARS-CoV-2 patient with cerebellar hemorrhage

(2020) Osama Al-Dalahmah et al.   Acta Neuropathologica Communications

The potential role of microvascular pathology in the neurological manifestations of coronavirus infection

(2020) M. A. MacLean et al.   Fluids and Barriers of the CNS

Age-related susceptibility to coronavirus infections: role of impaired and dysregulated host immunity

(2020) Rudragouda Channappanavar et al.   JOURNAL OF CLINICAL INVESTIGATION

Microglial cell depletion is fatal with low level picornavirus infection of the central nervous system

(2019) John Michael S. Sanchez et al.   JOURNAL OF NEUROVIROLOGY

CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis

(2019) Kristen E. Funk et al.   Journal of Neuroinflammation

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model

(2019) Elizabeth Spangenberg et al.   Nature Communications

Microglia are required for protection against lethal coronavirus encephalitis in mice

(2018) D. Lori Wheeler et al.   JOURNAL OF CLINICAL INVESTIGATION

Pharmacologic depletion of microglia increases viral load in the brain and enhances mortality in murine models of Flavivirus-induced encephalitis

(2018) Scott Seitz et al.   JOURNAL OF VIROLOGY

Microglia have a protective role in viral encephalitis-induced seizure development and hippocampal damage

(2018) Inken Waltl et al.   BRAIN BEHAVIOR AND IMMUNITY

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

(2017) Rudragouda Channappanavar et al.   Seminars in Immunopathology

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

(2014) Monica R.P. Elmore et al.   NEURON

Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes

(2012) The HD iPSC Consortium   Cell Stem Cell

Transgenic CCL2 Expression in the Central Nervous System Results in a Dysregulated Immune Response and Enhanced Lethality after Coronavirus Infection

(2012) J. A. Trujillo et al.   JOURNAL OF VIROLOGY

CXCL10 and trafficking of virus-specific T cells during coronavirus-induced demyelination

(2009) Linda N. Stiles et al.   AUTOIMMUNITY

Eukaryotic and archaeal translation initiation factor 2: A heterotrimeric tRNA carrier

(2009) Emmanuelle Schmitt et al.   FEBS LETTERS

A Protective Role for ELR+ Chemokines during Acute Viral Encephalomyelitis

(2009) Martin P. Hosking et al.   PLoS Pathogens