CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis

Csf1R inhibition attenuates experimental autoimmune encephalomyelitis and promotes recovery

(2018) Jillian C. Nissen et al.   EXPERIMENTAL NEUROLOGY

Microglia are required for protection against lethal coronavirus encephalitis in mice

(2018) D. Lori Wheeler et al.   JOURNAL OF CLINICAL INVESTIGATION

Pharmacologic depletion of microglia increases viral load in the brain and enhances mortality in murine models of Flavivirus-induced encephalitis

(2018) Scott Seitz et al.   JOURNAL OF VIROLOGY

Astrocytes decrease adult neurogenesis during virus-induced memory dysfunction via IL-1

(2018) Charise Garber et al.   NATURE IMMUNOLOGY

HVEM and CD160: Regulators of Immunopathology During Malaria Blood-Stage

(2018) Franziska Muscate et al.   Frontiers in Immunology

Microglial repopulation resolves inflammation and promotes brain recovery after injury

(2017) Rachel A. Rice et al.   GLIA

Microglia ablation alleviates myelin-associated catatonic signs in mice

(2017) Hana Janova et al.   JOURNAL OF CLINICAL INVESTIGATION

In vivo metabolic imaging of Traumatic Brain Injury

(2017) Caroline Guglielmetti et al.   Scientific Reports

An updated assessment of microglia depletion: current concepts and future directions

(2017) Jinming Han et al.   Molecular Brain

Colony-stimulating factor 1 receptor blockade prevents fractionated whole-brain irradiation-induced memory deficits

(2016) Xi Feng et al.   Journal of Neuroinflammation

A complement–microglial axis drives synapse loss during virus-induced memory impairment

(2016) Michael J. Vasek et al.   NATURE

Neuroinflammation — using big data to inform clinical practice

(2016) Calliope A. Dendrou et al.   Nature Reviews Neurology

Neuropsychological Impact of West Nile Virus Infection: An Extensive Neuropsychiatric Assessment of 49 Cases in Canada

(2016) Zainab Samaan et al.   PLoS One

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Emerging Roles for CSF-1 Receptor and its Ligands in the Nervous System

(2016) Violeta Chitu et al.   TRENDS IN NEUROSCIENCES

Elimination of microglia improves cognitive function following cranial irradiation

(2016) Munjal M. Acharya et al.   Scientific Reports

Microglia retard dengue virus-induced acute viral encephalitis

(2016) Tsung-Ting Tsai et al.   Scientific Reports

Long-Term Neurological Outcomes in West Nile Virus–Infected Patients: An Observational Study

(2015) Jill E. Weatherhead et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

CCR5 limits cortical viral loads during West Nile virus infection of the central nervous system

(2015) Douglas M. Durrant et al.   Journal of Neuroinflammation

Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice

(2015) Nabil N. Dagher et al.   Journal of Neuroinflammation

Activation of Intrinsic Immune Responses and Microglial Phagocytosis in an Ex Vivo Spinal Cord Slice Culture Model of West Nile Virus Infection

(2014) E. D. Quick et al.   JOURNAL OF VIROLOGY

Inflammation in neurodegenerative diseases - an update

(2013) Sandra Amor et al.   IMMUNOLOGY

KIT oncogene inhibition drives intratumoral macrophage M2 polarization

(2013) Michael J. Cavnar et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-1R1 is required for dendritic cell–mediated T cell reactivation within the CNS during West Nile virus encephalitis

(2013) Douglas M. Durrant et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation

(2012) Sayan Nandi et al.   DEVELOPMENTAL BIOLOGY

Estimated cumulative incidence of West Nile virus infection in US adults, 1999–2010

(2012) L. R. PETERSEN et al.   EPIDEMIOLOGY AND INFECTION

CSF-1 signaling mediates recovery from acute kidney injury

(2012) Ming-Zhi Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Flavivirus infection induces indoleamine 2,3-dioxygenase in human monocyte-derived macrophages via tumor necrosis factor and NF- B

(2012) A. W. S. Yeung et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages

(2012) Daniel R Getts et al.   Journal of Neuroinflammation

Inflammatory Effects of Highly Pathogenic H5N1 Influenza Virus Infection in the CNS of Mice

(2012) H. Jang et al.   JOURNAL OF NEUROSCIENCE

IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

(2012) Yaming Wang et al.   NATURE IMMUNOLOGY

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Normalized Median Fluorescence: An Alternative Flow Cytometry Analysis Method for Tracking Human Embryonic Stem Cell States During Differentiation

(2012) Lesley Y. Chan et al.   TISSUE ENGINEERING PART C-METHODS

Colony stimulating factors and myeloid cell biology in health and disease

(2012) John A. Hamilton et al.   TRENDS IN IMMUNOLOGY

2′-O Methylation of the Viral mRNA Cap by West Nile Virus Evades Ifit1-Dependent and -Independent Mechanisms of Host Restriction In Vivo

(2012) Kristy J. Szretter et al.   PLoS Pathogens

Reactive oxygen species drive herpes simplex virus (HSV)-1-induced proinflammatory cytokine production by murine microglia

(2011) Shuxian Hu et al.   Journal of Neuroinflammation

CD4 T Cells Promote CD8 T Cell Immunity at the Priming and Effector Site during Viral Encephalitis

(2011) T. W. Phares et al.   JOURNAL OF VIROLOGY

CNS Expression of B7-H1 Regulates Pro-Inflammatory Cytokine Production and Alters Severity of Theiler's Virus-Induced Demyelinating Disease

(2011) D'Anne S. Duncan et al.   PLoS One

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

(2010) Stephane Daffis et al.   NATURE

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Oxidative damage to neurons caused by the induction of microglial NADPH oxidase in encephalomyocarditis virus infection

(2009) Yasuhisa Ano et al.   NEUROSCIENCE LETTERS

Minocycline neuroprotects, reduces microglial activation, inhibits caspase 3 induction, and viral replication following Japanese encephalitis

(2008) Manoj Kumar Mishra et al.   JOURNAL OF NEUROCHEMISTRY

Japanese Encephalitis Virus infection induces IL-18 and IL-1β in microglia and astrocytes: Correlation with in vitro cytokine responsiveness of glial cells and subsequent neuronal death

(2008) Sulagna Das et al.   JOURNAL OF NEUROIMMUNOLOGY

CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis

(2008) E. E. McCandless et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

West Nile Virus Attenuates Activation of Primary Human Macrophages

(2008) Kok-Fai Kong et al.   VIRAL IMMUNOLOGY