C–H Insertion via Ruthenium Catalyzed gem-Hydrogenation of 1,3-Enynes

Light‐Driven gem Hydrogenation: An Orthogonal Entry into “Second‐Generation” Ruthenium Carbene Catalysts for Olefin Metathesis

(2021) Raphael J. Zachmann et al.   CHEMISTRY-A EUROPEAN JOURNAL

Dealkenylative Ni-Catalyzed Cross-Coupling Enabled by Tetrazine and Photoexcitation

(2021) Si-Cong Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrogenative Cycloisomerization and Sigmatropic Rearrangement Reactions of Cationic Ruthenium Carbenes Formed by Catalytic Alkyne gem ‐Hydrogenation

(2021) Tobias Biberger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cp*RuCl‐Vinyl Carbenes: Two Faces and the Bifunctional Role in Catalytic Processes

(2020) Damián Padín et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Advances in Ruthenium-Catalyzed Carbene/Alkyne Metathesis (CAM) Transformations

(2020) Damián Padín et al.   SYNLETT

Grubbs Metathesis Empowered by a Light‐Driven gem‐Hydrogenation of Internal Alkynes

(2020) Alois Fürstner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ru-Catalyzed Geminal Hydroboration of Silyl Alkynes via a New gem-Addition Mechanism

(2020) Qiang Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Opportunities for Tapping into Three-Dimensional Chemical Space through a Quaternary Carbon

(2020) Tanaji T. Talele   JOURNAL OF MEDICINAL CHEMISTRY

Hydrogenative Metathesis of Enynes via Piano-Stool Ruthenium Carbene Complexes Formed by Alkyne gem-Hydrogenation

(2020) Sebastian Peil et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Spirocyclic Scaffolds in Medicinal Chemistry

(2020) Kerstin Hiesinger et al.   JOURNAL OF MEDICINAL CHEMISTRY

Applications of deuterium in medicinal chemistry

(2019) Tracey Pirali et al.   JOURNAL OF MEDICINAL CHEMISTRY

Alkyne gem -Hydrogenation: Formation of Pianostool Ruthenium Carbene Complexes and Analysis of Their Chemical Character

(2019) Tobias Biberger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydrogenative Cyclopropanation and Hydrogenative Metathesis

(2019) Sebastian Peil et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydrodealkenylative C(sp3)–C(sp2) bond fragmentation

(2019) Andrew J. Smaligo et al.   SCIENCE

Mechanistic Divergence in the Hydrogenative Synthesis of Furans and Butenolides: Ruthenium Carbenes Formed by gem -Hydrogenation or through Carbophilic Activation of Alkynes

(2019) Sebastian Peil et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ru-Catalyzed Migratory Geminal Semihydrogenation of Internal Alkynes to Terminal Olefins

(2019) Lijuan Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dealkenylative Thiylation of C(sp3)–C(sp2) Bonds

(2019) Andrew J. Smaligo et al.   ORGANIC LETTERS

Oxodealkenylative Cleavage of Alkene C(sp3 )−C(sp2 ) Bonds: A Practical Method for Introducing Carbonyls into Chiral Pool Materials

(2019) Andrew J. Smaligo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences

(2018) Jens Atzrodt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Half-Sandwich Ruthenium Carbene Complexes Link trans-Hydrogenation and gem-Hydrogenation of Internal Alkynes

(2018) Alexandre Guthertz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

trans-Hydrogenation, gem-Hydrogenation, and trans-Hydrometalation of Alkynes: An Interim Report on an Unorthodox Reactivity Paradigm

(2018) Alois Fürstner   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fe-Catalyzed C–C Bond Construction from Olefins via Radicals

(2017) Julian C. Lo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium-Catalyzed Alkyne trans-Hydrometalation: Mechanistic Insights and Preparative Implications

(2017) Dragoş-Adrian Roşca et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mn-, Fe-, and Co-Catalyzed Radical Hydrofunctionalizations of Olefins

(2016) Steven W. M. Crossley et al.   CHEMICAL REVIEWS

Hydroxyl-Assisted trans-Reduction of 1,3-Enynes: Application to the Formal Synthesis of (+)-Aspicilin

(2016) Alois Fürstner et al.   SYNTHESIS-STUTTGART

Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

(2016) Alois Fürstner   ACS Central Science

Formation of Ruthenium Carbenes bygem-Hydrogen Transfer to Internal Alkynes: Implications for Alkynetrans-Hydrogenation

(2015) Markus Leutzsch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydrazone-Initiated Carbene/Alkyne Cascades to Form Polycyclic Products: Ring-Fused Cyclopropenes as Mechanistic Intermediates

(2015) Phong Q. Le et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interligand Interactions Dictate the Regioselectivity of trans-Hydrometalations and Related Reactions Catalyzed by [Cp*RuCl]. Hydrogen Bonding to a Chloride Ligand as a Steering Principle in Catalysis

(2015) Stephan M. Rummelt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Spiro Ketals, Orthoesters, and Orthocarbonates by CpRu-Catalyzed Decomposition of α-Diazo-β-ketoesters

(2015) Cecilia Tortoreto et al.   ORGANIC LETTERS

Diastereo- and enantioselective intramolecular 1,6-C–H insertion reactions of α-diazo esters catalyzed by chiral dirhodium(II) carboxylates

(2015) Motoki Ito et al.   TETRAHEDRON LETTERS

DFT and Kinetic Monte Carlo Study of TMS-Substituted Ruthenium Vinyl Carbenes: Key Intermediates for Stereoselective Cyclizations

(2015) Fermín Cambeiro et al.   ACS Catalysis

Advancement in Cascade [1,n]-Hydrogen Transfer/Cyclization: A Method for Direct Functionalization of Inactive C(sp3)H Bonds

(2014) Liang Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

CH Bond Functionalization through Intramolecular Hydride Transfer

(2014) Michael C. Haibach et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Vinyl Dihydropyrans and Dihydrooxazines: Cyclizations of Catalytic Ruthenium Carbenes Derived from Alkynals and Alkynones

(2014) Fermín Cambeiro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The use of spirocyclic scaffolds in drug discovery

(2014) Yajun Zheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Four-Membered Ring-Containing Spirocycles: Synthetic Strategies and Opportunities

(2014) Erick M. Carreira et al.   CHEMICAL REVIEWS

Synthesis of a Family of Spirocyclic Scaffolds: Building Blocks for the Exploration of Chemical Space

(2013) Sarvesh Kumar et al.   JOURNAL OF ORGANIC CHEMISTRY

Skeletal Diversification via Heteroatom Linkage Control: Preparation of Bicyclic and Spirocyclic Scaffolds from N-Substituted Homopropargyl Alcohols

(2013) Thomas O. Painter et al.   JOURNAL OF ORGANIC CHEMISTRY

Cyclohexanones by Rh-Mediated Intramolecular C–H Insertion

(2013) Douglass F. Taber et al.   JOURNAL OF ORGANIC CHEMISTRY

Construction of Multifunctional Modules for Drug Discovery: Synthesis of Novel Thia/Oxa-Azaspiro[3.4]octanes

(2013) Dong Bo Li et al.   ORGANIC LETTERS

Application of Parahydrogen Induced Polarization Techniques in NMR Spectroscopy and Imaging

(2012) Simon B. Duckett et al.   ACCOUNTS OF CHEMICAL RESEARCH

On the Interpretation of Deuterium Kinetic Isotope Effects in CH Bond Functionalizations by Transition-Metal Complexes

(2012) Eric M. Simmons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enol Acetal Synthesis through Carbenoid CH Insertion into Tetrahydrofuran Catalyzed by CpRu Complexes

(2012) Cecilia Tortoreto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Bridged Polycyclic Ring Systems via Carbene Cascades Terminating in C–H Bond Insertion

(2012) Santa Jansone-Popova et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Selective Intramolecular Carbene Insertion into Primary C–H Bond of α-Diazoacetamides Mediated by a (p-Cymene)ruthenium(II) Carboxylate Complex

(2012) Vanessa Kar-Yan Lo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cyclization by Catalytic Ruthenium Carbene Insertion into C sp 3H Bonds

(2011) Fermín Cambeiro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kinetic Isotope Effects in the Study of Organometallic Reaction Mechanisms

(2011) Mar Gómez-Gallego et al.   CHEMICAL REVIEWS

Highly Enantioselective Intramolecular Copper Catalyzed C−H Insertion Reactions of α-Diazosulfones

(2010) Christopher J. Flynn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium-Catalyzed Synthesis of Functional Conjugated Dienes via Addition of Two Carbene Units to Alkynes

(2010) Jacques Le Paih et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Carbene Insertion into C−H Bonds

(2009) Michael P. Doyle et al.   CHEMICAL REVIEWS

Transition metal-catalyzed C–H activation reactions: diastereoselectivity and enantioselectivity

(2009) Ramesh Giri et al.   CHEMICAL SOCIETY REVIEWS

Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion

(2008) Huw M. L. Davies et al.   NATURE