Next-Generation Serology by Mass Spectrometry: Readout of the SARS-CoV-2 Antibody Repertoire

Neutralizing antibody titres in SARS-CoV-2 infections

(2021) Eric H. Y. Lau et al.   Nature Communications

Analysis of SARS-CoV-2 antibodies in COVID-19 convalescent blood using a coronavirus antigen microarray

(2021) Rafael R. de Assis et al.   Nature Communications

Deep Sequencing of B Cell Receptor Repertoires From COVID-19 Patients Reveals Strong Convergent Immune Signatures

(2021) Jacob D. Galson et al.   Frontiers in Immunology

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

(2021) Pengfei Wang et al.   NATURE

Decoding the protein composition of whole nucleosomes with Nuc-MS

(2021) Luis F. Schachner et al.   NATURE METHODS

Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19

(2021) Adam K. Wheatley et al.   Nature Communications

SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19

(2021) Jun Wu et al.   Nature Communications

Provisional Mortality Data — United States, 2020

(2021) Farida B. Ahmad et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Convalescent Plasma Therapy for COVID-19: A Graphical Mosaic of the Worldwide Evidence

(2021) Stephen A. Klassen et al.   Frontiers in Medicine

Individual Ion Mass Spectrometry Enhances the Sensitivity and Sequence Coverage of Top-Down Mass Spectrometry

(2020) Jared O. Kafader et al.   JOURNAL OF PROTEOME RESEARCH

Native vs Denatured: An in Depth Investigation of Charge State and Isotope Distributions

(2020) Jared O. Kafader et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Multiplexed mass spectrometry of individual ions improves measurement of proteoforms and their complexes

(2020) Jared O. Kafader et al.   NATURE METHODS

A serological assay to detect SARS-CoV-2 seroconversion in humans

(2020) Fatima Amanat et al.   NATURE MEDICINE

Magnitude and kinetics of anti-SARS-CoV-2 antibody responses and their relationship to disease severity

(2020) Kara L Lynch et al.   CLINICAL INFECTIOUS DISEASES

Comorbidities and the risk of severe or fatal outcomes associated with coronavirus disease 2019: A systematic review and meta-analysis

(2020) Yue Zhou et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Convergent antibody responses to SARS-CoV-2 in convalescent individuals

(2020) Davide F. Robbiani et al.   NATURE

Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike

(2020) Lihong Liu et al.   NATURE

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

(2020) Lisa A. Jackson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

(2020) Thomas F. Rogers et al.   SCIENCE

Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients

(2020) Christoph Kreer et al.   CELL

Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population

(2020) Sabra L. Klein et al.   JOURNAL OF CLINICAL INVESTIGATION

Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults

(2020) Evan J. Anderson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Isotopic Resolution of Protein Complexes up to 466 kDa Using Individual Ion Mass Spectrometry

(2020) John P. McGee et al.   ANALYTICAL CHEMISTRY

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

(2020) Mads Delbo Larsen et al.   SCIENCE

Measurement of Individual Ions Sharply Increases the Resolution of Orbitrap Mass Spectra of Proteins

(2019) Jared Otto Kafader et al.   ANALYTICAL CHEMISTRY

The Pipeline Repertoire for Ig-Seq Analysis

(2019) Laura López-Santibáñez-Jácome et al.   Frontiers in Immunology

STORI Plots Enable Accurate Tracking of Individual Ion Signals

(2019) Jared O. Kafader et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Novel Interface for High-Throughput Analysis of Biotherapeutics by Electrospray Mass Spectrometry

(2019) Hae-Min Park et al.   ANALYTICAL CHEMISTRY

Accurate Sequence Analysis of a Monoclonal Antibody by Top-Down and Middle-Down Orbitrap Mass Spectrometry Applying Multiple Ion Activation Techniques

(2018) Luca Fornelli et al.   ANALYTICAL CHEMISTRY

A comprehensive pipeline for translational top-down proteomics from a single blood draw

(2018) Timothy K. Toby et al.   Nature Protocols

Analysis of Monoclonal Antibodies in Human Serum as a Model for Clinical Monoclonal Gammopathy by Use of 21 Tesla FT-ICR Top-Down and Middle-Down MS/MS

(2017) Lidong He et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

De Novo MS/MS Sequencing of Native Human Antibodies

(2016) Adrian Guthals et al.   JOURNAL OF PROTEOME RESEARCH

Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16

(2016) B M Gunn et al.   Mucosal Immunology

Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

(2016) Jiwon Lee et al.   NATURE MEDICINE

An informatic framework for decoding protein complexes by top-down mass spectrometry

(2016) Owen S Skinner et al.   NATURE METHODS

Complete De Novo Assembly of Monoclonal Antibody Sequences

(2016) Ngoc Hieu Tran et al.   Scientific Reports

Phenotyping Polyclonal Kappa and Lambda Light Chain Molecular Mass Distributions in Patient Serum Using Mass Spectrometry

(2014) David R. Barnidge et al.   JOURNAL OF PROTEOME RESEARCH

The promise and challenge of high-throughput sequencing of the antibody repertoire

(2014) George Georgiou et al.   NATURE BIOTECHNOLOGY

Proteoform: a single term describing protein complexity

(2013) Lloyd M Smith et al.   NATURE METHODS

Molecular deconvolution of the monoclonal antibodies that comprise the polyclonal serum response

(2013) Y. Wine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A proteomics approach for the identification and cloning of monoclonal antibodies from serum

(2012) Wan Cheung Cheung et al.   NATURE BIOTECHNOLOGY

Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose

(2011) C. Ferrara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS