Autophagy proteins in antigen processing for presentation on MHC molecules

Diverting autophagic membranes for exocytosis

(2015) Heike Nowag et al.   Autophagy

Differential use of autophagy by primary dendritic cells specialized in cross-presentation

(2015) Justine D Mintern et al.   Autophagy

KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation

(2015) C. R. Brooks et al.   EMBO JOURNAL

Live Long and Prosper for Antigen Cross-Presentation

(2015) Christian Münz   IMMUNITY

The Tumor Antigen NY-ESO-1 Mediates Direct Recognition of Melanoma Cells by CD4+T Cells after Intercellular Antigen Transfer

(2015) Jean Francois Fonteneau et al.   JOURNAL OF IMMUNOLOGY

Knockdown of Autophagy Inhibits Infectious Hepatitis C Virus Release by the Exosomal Pathway

(2015) Shubham Shrivastava et al.   JOURNAL OF VIROLOGY

PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins

(2015) David G. McEwan et al.   MOLECULAR CELL

Autophagic Degradation of the 26S Proteasome Is Mediated by the Dual ATG8/Ubiquitin Receptor RPN10 in Arabidopsis

(2015) Richard S. Marshall et al.   MOLECULAR CELL

Autophagy mediates degradation of nuclear lamina

(2015) Zhixun Dou et al.   NATURE

Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding

(2015) Hyunjoo Cha-Molstad et al.   NATURE CELL BIOLOGY

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

(2015) Jennifer Martinez et al.   NATURE CELL BIOLOGY

Autophagy and autophagy-related proteins in the immune system

(2015) Shusaku T Shibutani et al.   NATURE IMMUNOLOGY

Endogenous antigen processing drives the primary CD4+ T cell response to influenza

(2015) Michael A Miller et al.   NATURE MEDICINE

Dendritic Cell Autophagy Contributes to Herpes Simplex Virus-Driven Stromal Keratitis and Immunopathology

(2015) Yike Jiang et al.   mBio

p62 Plays a Specific Role in Interferon-γ-Induced Presentation of a Toxoplasma Vacuolar Antigen

(2015) Youngae Lee et al.   Cell Reports

Viral Inhibition of the Transporter Associated with Antigen Processing (TAP): A Striking Example of Functional Convergent Evolution

(2015) Marieke C. Verweij et al.   PLoS Pathogens

Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion

(2015) Min Zhang et al.   eLife

Investigating Evolutionary Conservation of Dendritic Cell Subset Identity and Functions

(2015) Thien-Phong Vu Manh et al.   Frontiers in Immunology

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation

(2014) Priyanka Nair-Gupta et al.   CELL

Molecular Mechanism of Autophagic Membrane-Scaffold Assembly and Disassembly

(2014) Anna Kaufmann et al.   CELL

Autophagy Induced by Calcium Phosphate Precipitates Targets Damaged Endosomes

(2014) Xi Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

First Signature of Islet  -Cell-Derived Naturally Processed Peptides Selected by Diabetogenic Class II MHC Molecules

(2014) A. Suri et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: FYCO1 Recruitment to Dectin-1 Phagosomes Is Accelerated by Light Chain 3 Protein and Regulates Phagosome Maturation and Reactive Oxygen Production

(2014) J. Ma et al.   JOURNAL OF IMMUNOLOGY

Therapeutic Antitumor Efficacy of B Cells Loaded With Tumor-derived Autophagasomes Vaccine (DRibbles)

(2014) Hongyan Ren et al.   JOURNAL OF IMMUNOTHERAPY

Cross-presentation of viral antigens in dribbles leads to efficient activation of virus-specific human memory t cells

(2014) Wei Ye et al.   Journal of Translational Medicine

Epstein-Barr Virus Blocks the Autophagic Flux and Appropriates the Autophagic Machinery To Enhance Viral Replication

(2014) M. Granato et al.   JOURNAL OF VIROLOGY

Modified Vaccinia Virus Ankara-Infected Dendritic Cells Present CD4+T-Cell Epitopes by Endogenous Major Histocompatibility Complex Class II Presentation Pathways

(2014) Frank Thiele et al.   JOURNAL OF VIROLOGY

Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy

(2014) Vladimir Rogov et al.   MOLECULAR CELL

Hijacking of an autophagy-like process is critical for the life cycle of a DNA virus infecting oceanic algal blooms

(2014) Daniella Schatz et al.   NEW PHYTOLOGIST

Regulation of SIV Antigen-Specific CD4+ T Cellular Immunity via Autophagosome-Mediated MHC II Molecule-Targeting Antigen Presentation in Mice

(2014) Yi Jin et al.   PLoS One

Nonlytic viral spread enhanced by autophagy components

(2014) S. W. Bird et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coxsackievirus B Exits the Host Cell in Shed Microvesicles Displaying Autophagosomal Markers

(2014) Scott M. Robinson et al.   PLoS Pathogens

Macroautophagy Proteins Assist Epstein Barr Virus Production and Get Incorporated Into the Virus Particles

(2014) Heike Nowag et al.   EBioMedicine

Historical landmarks of autophagy research

(2013) Yoshinori Ohsumi   CELL RESEARCH

Autophagy proteins stabilize pathogen-containing phagosomes for prolonged MHC II antigen processing

(2013) Susana Romao et al.   JOURNAL OF CELL BIOLOGY

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin

(2013) Naonobu Fujita et al.   JOURNAL OF CELL BIOLOGY

Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance

(2013) Martin Aichinger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Amphisomal Route of MHC Class I Cross-Presentation in Bacteria-Infected Dendritic Cells

(2013) D. Fiegl et al.   JOURNAL OF IMMUNOLOGY

A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells

(2013) Nicolas Pallet et al.   PROTEOMICS

Caspase activation regulates the extracellular export of autophagic vacuoles

(2012) Isabelle Sirois et al.   Autophagy

Autophagy inhibition promotes defective neosynthesized proteins storage in ALIS, and induces redirection toward proteasome processing and MHCI-restricted presentation

(2012) Till Wenger et al.   Autophagy

Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis

(2012) Hitoshi Nakatogawa et al.   Autophagy

Autophagy mediates transporter associated with antigen processing-independent presentation of viral epitopes through MHC class I pathway

(2012) S.-K. Tey et al.   BLOOD

The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes

(2012) Eisuke Itakura et al.   CELL

Dectin-1-triggered Recruitment of Light Chain 3 Protein to Phagosomes Facilitates Major Histocompatibility Complex Class II Presentation of Fungal-derived Antigens

(2012) Jun Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD4+ T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease

(2012) Antonella De Luca et al.   JOURNAL OF CLINICAL INVESTIGATION

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

(2012) Lei Liu et al.   NATURE CELL BIOLOGY

Herpes Simplex Virus  34.5 Interferes with Autophagosome Maturation and Antigen Presentation in Dendritic Cells

(2012) P. A. M. Gobeil et al.   mBio

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Tumor-Derived Autophagosome Vaccine: Mechanism of Cross-Presentation and Therapeutic Efficacy

(2011) Y. Li et al.   CLINICAL CANCER RESEARCH

Tumor-Derived Autophagosome Vaccine: Induction of Cross-Protective Immune Responses against Short-lived Proteins through a p62-Dependent Mechanism

(2011) C. G. Twitty et al.   CLINICAL CANCER RESEARCH

Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption

(2011) Carl J. DeSelm et al.   DEVELOPMENTAL CELL

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

(2011) Nicolas Dupont et al.   EMBO JOURNAL

Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells

(2011) Jamie M. Ireland et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Hsc/Hsp70 Co-Chaperone Network Controls Antigen Aggregation and Presentation during Maturation of Professional Antigen Presenting Cells

(2011) Nadja Kettern et al.   PLoS One

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

(2011) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cvt pathway as a model for selective autophagy

(2010) Melinda A. Lynch-Day et al.   FEBS LETTERS

In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells

(2010) Heung Kyu Lee et al.   IMMUNITY

Unconventional secretion of Acb1 is mediated by autophagosomes

(2010) Juan M. Duran et al.   JOURNAL OF CELL BIOLOGY

Unconventional secretion ofPichia pastorisAcb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation

(2010) Ravi Manjithaya et al.   JOURNAL OF CELL BIOLOGY

Rubicon and PLEKHM1 Negatively Regulate the Endocytic/Autophagic Pathway via a Novel Rab7-binding Domain

(2010) Keisuke Tabata et al.   MOLECULAR BIOLOGY OF THE CELL

Nuclear location of an endogenously expressed antigen, EBNA1, restricts access to macroautophagy and the range of CD4 epitope display

(2010) C. S. Leung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways

(2009) Claudio Marcelo Fader et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells

(2009) M Uhl et al.   CELL DEATH AND DIFFERENTIATION

Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy

(2009) Tomotake Kanki et al.   DEVELOPMENTAL CELL

Host ER–parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation inToxoplasma gondii–infected dendritic cells

(2009) Romina S. Goldszmid et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autophagic Compartments Gain Access to the MHC Class II Compartments in Thymic Epithelium

(2009) M. Kasai et al.   JOURNAL OF IMMUNOLOGY

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex

(2009) Yun Zhong et al.   NATURE CELL BIOLOGY

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

(2009) Kohichi Matsunaga et al.   NATURE CELL BIOLOGY

Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection

(2009) Luc English et al.   NATURE IMMUNOLOGY

Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells

(2009) Chinnaswamy Jagannath et al.   NATURE MEDICINE

Efficient Cross-presentation Depends on Autophagy in Tumor Cells

(2008) Y. Li et al.   CANCER RESEARCH

Autophagy regulates selective HMGB1 release in tumor cells that are destined to die

(2008) J Thorburn et al.   CELL DEATH AND DIFFERENTIATION

Endogenous presentation of a nuclear antigen on MHC class II by autophagy in the absence of CRM1-mediated nuclear export

(2008) Alexander Riedel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Ordered Organelle Degradation during Starvation-induced Autophagy

(2008) Anders Riis Kristensen et al.   MOLECULAR & CELLULAR PROTEOMICS

Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance

(2008) Jelena Nedjic et al.   NATURE

Essential role for Nix in autophagic maturation of erythroid cells

(2008) Hector Sandoval et al.   NATURE