Kaempferol reduces obesity, prevents intestinal inflammation, and modulates gut microbiota in high-fat diet mice

Rebalancing of the gut flora and microbial metabolism is responsible for the anti-arthritis effect of kaempferol

(2019) Li-xiang Aa et al.   ACTA PHARMACOLOGICA SINICA

Protective Effect of Kaempferol on LPS-Induced Inflammation and Barrier Dysfunction in a Coculture Model of Intestinal Epithelial Cells and Intestinal Microvascular Endothelial Cells

(2019) Yifei Bian et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The metabolic and vascular protective effects of olive (Olea europaea L.) leaf extract in diet-induced obesity in mice are related to the amelioration of gut microbiota dysbiosis and to its immunomodulatory properties

(2019) Teresa Vezza et al.   PHARMACOLOGICAL RESEARCH

Natural dietary compound naringin prevents azoxymethane/dextran sodium sulfate-induced chronic colorectal inflammation and carcinogenesis in mice

(2018) Yu-Sheng Zhang et al.   CANCER BIOLOGY & THERAPY

Chitosan oligosaccharides improve the disturbance in glucose metabolism and reverse the dysbiosis of gut microbiota in diabetic mice

(2018) Junping Zheng et al.   CARBOHYDRATE POLYMERS

Kaempferol ameliorates hyperglycemia through suppressing hepatic gluconeogenesis and enhancing hepatic insulin sensitivity in diet-induced obese mice

(2018) Hana Alkhalidy et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Chitin Oligosaccharide Modulates Gut Microbiota and Attenuates High-Fat-Diet-Induced Metabolic Syndrome in Mice

(2018) Junping Zheng et al.   Marine Drugs

Anti-diabetic effect of baicalein is associated with the modulation of gut microbiota in streptozotocin and high-fat-diet induced diabetic rats

(2018) Bowei Zhang et al.   Journal of Functional Foods

(-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance

(2018) Eleonora Cremonini et al.   Redox Biology

Quercetin Attenuates Adhesion Molecule Expression in Intestinal Microvascular Endothelial Cells by Modulating Multiple Pathways

(2018) Yifei Bian et al.   DIGESTIVE DISEASES AND SCIENCES

A low dose lipid infusion is sufficient to induce insulin resistance and a pro-inflammatory response in human subjects

(2018) Hanyu Liang et al.   PLoS One

Anti-obesity effects of kaempferol by inhibiting adipogenesis and increasing lipolysis in 3T3-L1 cells

(2018) D. Torres-Villarreal et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

A higher flavonoid intake is associated with less likelihood of nonalcoholic fatty liver disease: results from a multiethnic study

(2018) Mohsen Mazidi et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related gut-liver axis activation

(2017) David Porras et al.   FREE RADICAL BIOLOGY AND MEDICINE

Impaired Intestinal Permeability Contributes to Ongoing Bowel Symptoms in Patients With Inflammatory Bowel Disease and Mucosal Healing

(2017) Jeff Chang et al.   GASTROENTEROLOGY

Gut-Specific Delivery of T-Helper 17 Cells Reduces Obesity and Insulin Resistance in Mice

(2017) Chun-Pyo Hong et al.   GASTROENTEROLOGY

Gut microbiome and liver diseases

(2016) Herbert Tilg et al.   GUT

Obesity in IBD: epidemiology, pathogenesis, disease course and treatment outcomes

(2016) Siddharth Singh et al.   Nature Reviews Gastroenterology & Hepatology

Effects of flavonoids on intestinal inflammation, barrier integrity and changes in gut microbiota during diet-induced obesity

(2016) Katherine Gil-Cardoso et al.   NUTRITION RESEARCH REVIEWS

Apple-Derived Pectin Modulates Gut Microbiota, Improves Gut Barrier Function, and Attenuates Metabolic Endotoxemia in Rats with Diet-Induced Obesity

(2016) Tingting Jiang et al.   Nutrients

Regulation of Obesity-Related Insulin Resistance with Gut Anti-inflammatory Agents

(2015) Helen Luck et al.   Cell Metabolism

The Gut Microbiota Regulates Intestinal CD4 T Cells Expressing RORγt and Controls Metabolic Disease

(2015) Lucile Garidou et al.   Cell Metabolism

Kaempferol alleviates insulin resistance via hepatic IKK/NF-κB signal in type 2 diabetic rats

(2015) Cheng Luo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The anti-obesity and anti-diabetic effects of kaempferol glycosides from unripe soybean leaves in high-fat-diet mice

(2015) Yanqing Zang et al.   Food & Function

Curcumin attenuates inflammatory responses by suppressing TLR4-mediated NF-κB signaling pathway in lipopolysaccharide-induced mastitis in mice

(2014) Yunhe Fu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Gut microbiome composition and function in experimental colitis during active disease and treatment-induced remission

(2014) Michelle G Rooks et al.   ISME Journal

Imbalance between Neutrophil Elastase and its Inhibitor α1-Antitrypsin in Obesity Alters Insulin Sensitivity, Inflammation, and Energy Expenditure

(2013) Virginie Mansuy-Aubert et al.   Cell Metabolism

Supplemental Naringenin Prevents Intestinal Barrier Defects and Inflammation in Colitic Mice

(2013) Tomoyo Azuma et al.   JOURNAL OF NUTRITION

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut microbiota controls adipose tissue expansion, gut barrier and glucose metabolism: novel insights into molecular targets and interventions using prebiotics

(2013) L. Geurts et al.   Beneficial Microbes

Dietary Kaempferol Suppresses Inflammation of Dextran Sulfate Sodium-Induced Colitis in Mice

(2011) Mi-Young Park et al.   DIGESTIVE DISEASES AND SCIENCES

Inflammatory links between obesity and metabolic disease

(2011) Carey N. Lumeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Kaempferol Suppresses Eosionphil Infiltration and Airway Inflammation in Airway Epithelial Cells and in Mice with Allergic Asthma

(2011) Ju-Hyun Gong et al.   JOURNAL OF NUTRITION

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models

(2010) E F Murphy et al.   GUT

Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression in LETO and OLETF rats

(2010) Takuya Suzuki et al.   Nutrition & Metabolism

Intestinal, adipose, and liver inflammation in diet-induced obese mice

(2008) Hong Li et al.   METABOLISM-CLINICAL AND EXPERIMENTAL