CXCR4-targeted nanotoxins induce GSDME-dependent pyroptosis in head and neck squamous cell carcinoma

Switching from Apoptosis to Pyroptosis: Gasdermin-Elicited Inflammation and Antitumor Immunity

(2021) Kohsuke Tsuchiya   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cell death in head and neck cancer pathogenesis and treatment

(2021) Martina Raudenská et al.   Cell Death & Disease

Induction of Pyroptosis: A Promising Strategy for Cancer Treatment

(2021) Lei Wang et al.   Frontiers in Oncology

Molecular Mechanisms of Chemotherapy Resistance in Head and Neck Cancers

(2021) Yuzuka Kanno et al.   Frontiers in Oncology

Recent development and optimization of pseudomonas aeruginosa exotoxin immunotoxins in cancer therapeutic applications

(2021) Tong Wu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Therapeutic Potential of Antibody-Drug Conjugate-Based Therapy in Head and Neck Cancer: A Systematic Review

(2021) Vittoria Perrotti et al.   Cancers

Self-assembling protein nanocarrier for selective delivery of cytotoxic polypeptides to CXCR4+ head and neck squamous cell carcinoma tumors

(2021) Elisa Rioja-Blanco et al.   Acta Pharmaceutica Sinica B

A novel 3’,5’-diprenylated chalcone induces concurrent apoptosis and GSDME-dependent pyroptosis through activating PKCδ/JNK signal in prostate cancer

(2020) Yongqiang Zhang et al.   Aging-US

Gasdermin E suppresses tumour growth by activating anti-tumour immunity

(2020) Zhibin Zhang et al.   NATURE

Miltirone induces cell death in hepatocellular carcinoma cell through GSDME-dependent pyroptosis

(2020) Xiaowei Zhang et al.   Acta Pharmaceutica Sinica B

Cell Death Mediated by the Pyroptosis Pathway with the Aid of Nanotechnology: Prospects for Cancer Therapy

(2020) Dan Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions

(2020) Meng Liu et al.   Nature Communications

Head and neck squamous cell carcinoma

(2020) Daniel E. Johnson et al.   Nature Reviews Disease Primers

High NOR-1 (Neuron-Derived Orphan Receptor 1) Expression Strengthens the Vascular Wall Response to Angiotensin II Leading to Aneurysm Formation in Mice

(2020) Laia Cañes et al.   HYPERTENSION

Safety and Tolerability of Antibody-Drug Conjugates in Cancer

(2019) Anna Wolska-Washer et al.   DRUG SAFETY

A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma

(2019) Mengjiao Wu et al.   EBioMedicine

Chemotherapeutic paclitaxel and cisplatin differentially induce pyroptosis in A549 lung cancer cells via caspase-3/GSDME activation

(2019) Cheng-cheng Zhang et al.   APOPTOSIS

A CXCR4-targeted nanocarrier achieves highly selective tumor uptake in diffuse large B-cell lymphoma mouse models

(2019) Aïda Falgàs et al.   HAEMATOLOGICA

The changing therapeutic landscape of head and neck cancer

(2019) John D. Cramer et al.   Nature Reviews Clinical Oncology

The role of pyroptosis in cancer: pro-cancer or pro-“host”?

(2019) Xiaojing Xia et al.   Cell Death & Disease

The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma

(2019) Yang Kong et al.   Frontiers in Oncology

Induction of Pyroptosis and Its Implications in Cancer Management

(2019) Yan-Yang Wang et al.   Frontiers in Oncology

Critical Issues in the Development of Immunotoxins for Anticancer Therapy

(2019) Ji-Sun Kim et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Self-assembling toxin-based nanoparticles as self-delivered antitumoral drugs

(2018) Laura Sánchez-García et al.   JOURNAL OF CONTROLLED RELEASE

SDF-1/CXCR4 expression is an independent negative prognostic biomarker in patients with head and neck cancer after primary radiochemotherapy

(2018) Chiara De-Colle et al.   RADIOTHERAPY AND ONCOLOGY

Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis 

(2018) Bo Zhou et al.   CELL RESEARCH

Molecular Markers of Anticancer Drug Resistance in Head and Neck Squamous Cell Carcinoma: A Literature Review

(2018) Sandra López-Verdín et al.   Cancers

Clinical toxicity of antibody drug conjugates: a meta-analysis of payloads

(2017) Joanna C. Masters et al.   INVESTIGATIONAL NEW DRUGS

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Strategies and challenges for the next generation of antibody–drug conjugates

(2017) Alain Beck et al.   NATURE REVIEWS DRUG DISCOVERY

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses

(2017) Darshan S. Chandrashekar et al.   NEOPLASIA

Expression of the CXCL12/CXCR4 chemokine axis predicts regional control in head and neck squamous cell carcinoma

(2016) Xavier León et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

Current Treatment Options for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

(2015) Assuntina G. Sacco et al.   JOURNAL OF CLINICAL ONCOLOGY

Advances in Anticancer Immunotoxin Therapy

(2015) C. Alewine et al.   ONCOLOGIST

In Vivo Architectonic Stability of Fully de Novo Designed Protein-Only Nanoparticles

(2014) María Virtudes Céspedes et al.   ACS Nano

Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer

(2008) Myoung Sook Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma

(2008) M S Kim et al.   ONCOGENE

Mesothelin targeted cancer immunotherapy

(2007) Raffit Hassan et al.   EUROPEAN JOURNAL OF CANCER