Ginseng root extract attenuates inflammation by inhibiting the MAPK/NF-κB signaling pathway and activating autophagy and p62-Nrf2-Keap1 signaling in vitro and in vivo

Pectin-Lyase-Modified Ginseng Extract and Ginsenoside Rd Inhibits High Glucose-Induced ROS Production in Mesangial Cells and Prevents Renal Dysfunction in db/db Mice

(2021) Eunsoo Jung et al.   MOLECULES

The antioxidant activities of Korean red ginseng (Panax ginseng) and ginsenosides: A systemic review through in vivo and clinical trials

(2020) Soo Kyung Park et al.   Journal of Ginseng Research

Ginseng berry polysaccharides on inflammation-associated colon cancer: inhibiting T-cell differentiation, promoting apoptosis, and enhancing the effects of 5-fluorouracil

(2019) Chong-Zhi Wang et al.   Journal of Ginseng Research

Ginseng protein protects against mitochondrial dysfunction and neurodegeneration by inducing mitochondrial unfolded protein response in Drosophila melanogaster PINK1 model of Parkinson's disease

(2019) Meichen Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Ulinastatin attenuates LPS-induced inflammation in mouse macrophage RAW264.7 cells by inhibiting the JNK/NF-κB signaling pathway and activating the PI3K/Akt/Nrf2 pathway

(2018) Si-tong Li et al.   ACTA PHARMACOLOGICA SINICA

Role of p62 in the regulation of cell death induction

(2018) Lihong Fan et al.   APOPTOSIS

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway

(2018) Shi-feng Chu et al.   ACTA PHARMACOLOGICA SINICA

TAK1 Regulates the Nrf2 Antioxidant System Through Modulating p62/SQSTM1

(2016) Kazunori Hashimoto et al.   ANTIOXIDANTS & REDOX SIGNALING

Shaping the spectrum — From autoinflammation to autoimmunity

(2016) Christian M. Hedrich   CLINICAL IMMUNOLOGY

FoxO1-mediated autophagy is required for NK cell development and innate immunity

(2016) Shuo Wang et al.   Nature Communications

Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease

(2015) Lauren E. Tebay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation

(2015) Xiaorong Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

Red Ginseng and Semen Coicis can improve the structure of gut microbiota and relieve the symptoms of ulcerative colitis

(2015) Mingzhang Guo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease

(2015) Brent J. Ryan et al.   TRENDS IN BIOCHEMICAL SCIENCES

Macrophage Polarization in Inflammatory Diseases

(2014) Yan-Cun Liu et al.   International Journal of Biological Sciences

Activation of nuclear factor erythroid 2-related factor 2 (Nrf2) and Nrf-2-dependent genes by ischaemic pre-conditioning and post-conditioning: new adaptive endogenous protective responses against renal ischaemia/reperfusion injury

(2013) A. A. Shokeir et al.   Acta Physiologica

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

(2013) Yoshinobu Ichimura et al.   MOLECULAR CELL

Concepts of oxidative stress and antioxidant defense in Crohn’s disease

(2013) Mohammed A Alzoghaibi   WORLD JOURNAL OF GASTROENTEROLOGY

Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF-κB in LPS-stimulated RAW264.7 cells and mouse liver

(2013) Dae Hyun Kim et al.   Journal of Ginseng Research

Structure and biological activities of the polysaccharides from the leaves, roots and fruits of Panax ginseng C.A. Meyer: An overview

(2011) Yongxu Sun   CARBOHYDRATE POLYMERS

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole

(2011) Yumi Abiko et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Linking oxidative stress to inflammation: Toll-like receptors

(2010) Roop Gill et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inflammatory Bowel Disease

(2009) Clara Abraham et al.   NEW ENGLAND JOURNAL OF MEDICINE

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL