Korean red ginseng alleviate depressive disorder by improving astrocyte gap junction function

Dysfunction of astrocytic connexins 30 and 43 in the medial prefrontal cortex and hippocampus mediates depressive-like behaviours

(2019) Dongming Huang et al.   BEHAVIOURAL BRAIN RESEARCH

New Hope for Patients with Major Depressive Disorder?

(2019) Emil F. Coccaro   NEW ENGLAND JOURNAL OF MEDICINE

Intracellular trafficking pathways of Cx43 gap junction channels

(2018) Irina Epifantseva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A novel mechanism of depression: role for connexins

(2018) Cong-Yuan Xia et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

TAT-Gap19 and Carbenoxolone Alleviate Liver Fibrosis in Mice

(2018) Sara Crespo Yanguas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Roles of astrocytic connexin-43, hemichannels, and gap junctions in oxygen-glucose deprivation/reperfusion injury induced neuroinflammation and the possible regulatory mechanisms of salvianolic acid B and carbenoxolone

(2018) Xiang Yin et al.   Journal of Neuroinflammation

Astrocytic gap junction inhibition by carbenoxolone enhances the protective effects of ischemic preconditioning following cerebral ischemia

(2018) Di Ma et al.   Journal of Neuroinflammation

Corticosterone impairs gap junctions in the prefrontal cortical and hippocampal astrocytes via different mechanisms

(2018) Cong-Yuan Xia et al.   NEUROPHARMACOLOGY

Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions

(2018) Padmanaban Mohanan et al.   Journal of Ginseng Research

Therapeutic Targeting of Connexin Channels: New Views and Challenges

(2018) Tinneke Delvaeye et al.   TRENDS IN MOLECULAR MEDICINE

Suppressive Effect of Ginsenoside Rg3 against Lipopolysaccharide-Induced Depression-Like Behavior and Neuroinflammation in Mice

(2017) An Kang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Mesoporous hydroxyapatite as a carrier of olanzapine for long-acting antidepression treatment in rats with induced depression

(2017) Yan-Jye Shyong et al.   JOURNAL OF CONTROLLED RELEASE

Ginsenoside Rg1 alleviates corticosterone-induced dysfunction of gap junctions in astrocytes

(2017) Cong-Yuan Xia et al.   JOURNAL OF ETHNOPHARMACOLOGY

Galanin (1-15) enhancement of the behavioral effects of Fluoxetine in the forced swimming test gives a new therapeutic strategy against depression

(2017) Antonio Flores-Burgess et al.   NEUROPHARMACOLOGY

Gap junction channels as potential targets for the treatment of major depressive disorder

(2017) Qian Ren et al.   PSYCHOPHARMACOLOGY

Glucocorticoid Suppresses Connexin 43 Expression by Inhibiting the Akt/mTOR Signaling Pathway in Osteoblasts

(2016) Chen Shen et al.   CALCIFIED TISSUE INTERNATIONAL

Subgenual anterior cingulate cortex and hippocampal volumes in depressed youth: The role of comorbidity and age

(2016) Natalia Jaworska et al.   JOURNAL OF AFFECTIVE DISORDERS

Protective effects of Forsythia suspense extract with antioxidant and anti-inflammatory properties in a model of rotenone induced neurotoxicity

(2016) Shuai Zhang et al.   NEUROTOXICOLOGY

Astrocyte plasticity induced by emotional stress: A new partner in psychiatric physiopathology?

(2016) Crhistian L. Bender et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Les jonctions gap : une nouvelle cible thérapeutique pour le traitement des troubles dépressifs majeurs ?

(2015) D. Sarrouilhe et al.   REVUE NEUROLOGIQUE

Attenuated Levels of Hippocampal Connexin 43 and its Phosphorylation Correlate with Antidepressant- and Anxiolytic-Like Activities in Mice

(2015) Gaël Quesseveur et al.   Frontiers in Cellular Neuroscience

Characterization of Korean Red Ginseng (Panax ginseng Meyer): History, preparation method, and chemical composition

(2015) Sang Myung Lee et al.   Journal of Ginseng Research

Chronic corticosterone-mediated dysregulation of microRNA network in prefrontal cortex of rats: relevance to depression pathophysiology

(2015) Y Dwivedi et al.   Translational Psychiatry

Effect of Korean Red Ginseng as an adjuvant treatment for women with residual symptoms of major depression

(2014) Hyun-Ghang Jeong et al.   Asia-Pacific Psychiatry

Korean Red Ginseng Extract Exhibits Neuroprotective Effects through Inhibition of Apoptotic Cell Death

(2014) Sunyoung Kim et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Chronic stress-induced disruption of the astrocyte network is driven by structural atrophy and not loss of astrocytes

(2013) Ross J. Tynan et al.   ACTA NEUROPATHOLOGICA

Astrocyte Pathology in Major Depressive Disorder: Insights from Human Postmortem Brain Tissue

(2013) Grazyna Rajkowska et al.   CURRENT DRUG TARGETS

Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010

(2013) Harvey A Whiteford et al.   LANCET

The effect of fermented red ginseng on depression is mediated by lipids

(2013) Kwang Jo Lee et al.   NUTRITIONAL NEUROSCIENCE

Autoregulation of Connexin43 Gap Junction Formation by Internally Translated Isoforms

(2013) James W. Smyth et al.   Cell Reports

Antidepressant-like Effect of Altered Korean Red Ginseng in Mice

(2011) Na-Hyung Kim et al.   BEHAVIORAL MEDICINE

Dysfunction of Astrocyte Connexins 30 and 43 in Dorsal Lateral Prefrontal Cortex of Suicide Completers

(2011) Carl Ernst et al.   BIOLOGICAL PSYCHIATRY

Gap Junction Dysfunction in the Prefrontal Cortex Induces Depressive-Like Behaviors in Rats

(2011) Jian-Dong Sun et al.   NEUROPSYCHOPHARMACOLOGY

Nongenomic glucocorticoid receptor action regulates gap junction intercellular communication and neural progenitor cell proliferation

(2011) R. A. Samarasinghe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered expression of glutamate signaling, growth factor and glia genes in the locus coeruleus of patients with major depression

(2010) R Bernard et al.   MOLECULAR PSYCHIATRY

Astroglial networks: a step further in neuroglial and gliovascular interactions

(2010) Christian Giaume et al.   NATURE REVIEWS NEUROSCIENCE

The functional neuroanatomy of depression: Distinct roles for ventromedial and dorsolateral prefrontal cortex

(2009) Michael Koenigs et al.   BEHAVIOURAL BRAIN RESEARCH

Prostaglandin Promotion of Osteocyte Gap Junction Function through Transcriptional Regulation of Connexin 43 by Glycogen Synthase Kinase 3/ -Catenin Signaling

(2009) X. Xia et al.   MOLECULAR AND CELLULAR BIOLOGY

Excitability and gap junction–mediated mechanisms in nucleus accumbens regulate self-stimulation reward in rats

(2009) L. Kokarovtseva et al.   NEUROSCIENCE

Glial Loss in the Prefrontal Cortex Is Sufficient to Induce Depressive-like Behaviors

(2008) Mounira Banasr et al.   BIOLOGICAL PSYCHIATRY

Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission

(2008) N. Rouach et al.   SCIENCE